This chapter addresses a classic topic: the advancement of science. In the wake of Kuhn’s groundbreaking work, positivist philosophy of science was replaced by a more realistic and historically informed depiction of science. However, over half a century has now passed since the publication of Structure. Despite valiant attempts, we still lack a fully developed, viable replacement for the cumulative model presupposed by positivism. At the dawn of the new millennium, mainstream philosophy eventually abandoned the project of developing a grand, overarching account of science. The quest for generality was traded in for a more detailed analysis of particular disciplines and practices. The goal of this chapter is to show how the black-boxing strategy can offer a revamped formulation of scientific progress, an important topic that lies at the core of any general characterization of science, and bring it back on the philosophical main stage, where it legitimately belongs.