This chapter focuses on the impact of field quantization methods on the problem of quantum gravity. It is shown that much work after 1930 until mid-century was an exercise in ‘exploring the consequences’ of the Heisenberg-Pauli theory of quantum electrodynamics: understanding the symmetries and the divergences, and attempting to find ways of dealing with both. The goal was very much to treat all fields in much the same way, and so one could also envisage learning about one field from another. However, there was a separate track, superficially similar, though issuing from a desire to have a theory of gravitation more in line with the rest of physics, and in particular one not involving the difficulties of curved, dynamical spacetime. The interaction representation and a desire for a manifestly covariant description played a crucial role in the development of such approaches, and involved a curious borrowing of concepts often associated with canonical approaches. An apparently orthogonal approach developed alongside these later manifestly covariant approaches, involving a hybrid approach retaining a classical gravitational field, albeit still coupled to quantized sources through the Einstein field equations. These were done largely to avoid complications, however, and the conceptual consequences, though hinted at, were not further explored.