Securing Biodiversity, Functional Integrity, and Ecosystem Services in Drying River Networks (DRYvER)

River networks are among Earth’s most threatened hot-spots of biodiversity and provide key ecosystem services (e.g., supply drinking water and food, climate regulation) essential to sustaining human well-being. Climate change and increased human water use are causing more rivers and streams to dry, with devastating impacts on biodiversity and ecosystem services. Currently, more than a half of the global river networks consist of drying channels, and these are expanding dramatically. However, drying river networks (DRNs) have received little attention from scientists and policy makers, and the public is unaware of their importance. Consequently, there is no effective integrated biodiversity conservation or ecosystem management strategy of DRNs. A multidisciplinary team of 25 experts from 11 countries in Europe, South America, China and the USA will build on EU efforts to assess the cascading effects of climate change on biodiversity, ecosystem functions and ecosystem services of DRNs through changes in flow regimes and water use. DRYvER (DRYing riVER networks) will gather and upscale empirical and modelling data from nine focal DRNs (case studies) in Europe (EU) and Community of Latin American and Caribbean States (CELAC) to develop a meta-system framework applicable to Europe and worldwide. It will also generate crucial knowledge-based strategies, tools and guidelines for economically-efficient adaptive management of DRNs. Working closely with stakeholders and end-users, DRYvER will co-develop strategies to mitigate and adapt to climate change impacts in DRNs, integrating hydrological, ecological (including nature-based solutions), socio-economic and policy perspectives. The end results of DRYvER will contribute to reaching the objectives of the Paris Agreement and placing Europe at the forefront of research on climate change.

Documentation of a public communication project by German-speaking scientists prior to the September 2021 climate demonstrations

English: Documentation of a communication project by German-speaking scientists encouraging their peers to participate in the September 2021 climate demonstrations by means of short statements or appeals (German, with English and French translations). Deutsch: Dokumentation eines Kommunikationsprojekts deutschsprachiger Wissenschaftler:innen, ihre Kolleg:innen mit kurzen Statements oder Aufrufen zur Teilnahme an den Klimademonstrationen im September 2021 zu ermuntern (deutsch, mit englischer und französischer Übersetzung). Français: Documentation d'un projet de communication de scientifiques germanophones visant à encourager leurs collègues à participer aux manifestations pour le climat en septembre 2021 par de courtes déclarations ou des appels (en allemand, avec traduction en anglais et en français).

The Value of Digitising Natural History Collections

The Natural History Museum, London has been creating digital data about collections for many years, with a formal Digital Collections Programme since 2014. Efforts to monitor the outcomes and impact of this work have focused on metrics of digital access, such as download events, and on citations of digital specimens as a measure of use. Digitisation projects and resulting research have also been used as impact case studies, highlighting areas such as human health and conservation. In 2021, the Museum decided to explore the economic impacts of collections data in more depth, and commissioned Frontier Economics to undertake modelling, resulting in this report. While the methods in this report are relevant to collections globally, this modelling focuses on benefits to the UK, and is intended to support the Museum’s own digitisation work, as well as a current scoping study funded by the Arts & Humanities Research Council about the case for digitising all UK natural science collections as a research infrastructure. This study focuses on digitisation in the round, not distinguishing between different collection types or levels of data creation at this stage. Three methods have been used: first, analysing five key thematic areas or sectors where data from natural science collections are likely to lead to benefits; secondly, analysing typical returns on investment in scientific research; and thirdly, examining the efficiency savings that can be reinvested in research if data are available freely and openly. Together, these methods confirm benefits in excess of £2 billion over 30 years, representing a seven to ten times return on investment.

RECLAMO: Unlocking the potential of wastewater reuse for agricultural irrigation in Spain

Increasing water scarcity is encouraging the use of unconventional water resources. In recent years, the European Union has launched numerous initiatives to promote and facilitate water reuse for agricultural irrigation. Today, the use of reclaimed water for agriculture has become an alternative, reliable and safe source of water supply and an indispensable water planning tool, especially in the area of southern Europe. However, water reuse for irrigation is currently far below its potential. Numerous barriers prevent its development and call for a detailed analysis of the different aspects affecting reclaimed water reuse, through an integrated and multidisciplinary approach. A multidisciplinary research team from Universidad Politécnica de Madrid, consisting of agronomists, hydrologists, chemists and agricultural economists, will work on the RECLAMO Project (https://blogs.upm.es/reclamo/), with the aim of providing solutions and recommendations aimed at promoting the full development and use of reclaimed water for irrigation in areas of Spain with marked water stress. For this purpose, project activities will be developed in two selected case studies (the Segura Basin, leader in water reuse in Spain and the Guadiana Basin, with success stories, but low levels of water reuse) and organised according to five axes: 1) development of a comprehensive knowledge-base covering the regulatory, technical, socio-economic and environmental aspects of reclaimed water reuse in agriculture; 2) participatory development of future scenarios exploring possible strategies, barriers and opportunities, in relation to the expansion of the use of reclaimed water for irrigation; 3) impact analysis of the strategies identified at different scales (crop, farm, (sub-)basin), through the development of an integrated modelling platform (hydrologic-agronomic-economic models); 4) Development of a roadmap and policy recommendations to achieve the full development and use of reclaimed water reuse for irrigation; 5) Dissemination of knowledge and promotion of science-policy-society dialogue. To this end, RECLAMO will collaborate closely with experts and stakeholder groups that will play a key role in the project in co-creating the scenarios and modelling tools and validating the results. The project will also seek for synergies and complementarities with other similar projects and explore new ways of collaborating with companies and research groups that allow research to continue and expand beyond the spatial and temporal limits of the project. RECLAMO’s results will promote an integrated approach to the sustainable management of water resources in water-stressed areas, including reclaimed water management. The integrated modelling platform developed in the project will allow policy-makers and water users to benefit from an improved understanding of the interactions between the social, economic and environmental aspects of water systems, in the context of climate and socio-economic change that will lead to better informed decision-making to address future water challenges. In addition, RECLAMO is expected to contribute to raising awareness about the use of reclaimed water reuse in agriculture as a safe and sustainable practice and to improve its social acceptance by producing science-based knowledge that provide evidence on the benefits derived from its use.

Dataset: Feedback on the Path2Integrity learning cards for research integrity (2020)

This dataset is drawn from feedback given by participants, lecturers, and experts on the Path2Integrity learning cards programme for research integrity in 2020. Positive as well as negative feedback is presented, thus recording what went well, what did not, and what must be improved. The data collected is viewed as crucial for the further development of tools for teaching and learning research integrity, in particular Path2Integrity’s learning cards.

Epidemiological Trends for Cryptococcosis in Swaziland (Eswatini), Southern Africa

Cryptococcosis is a fungal disease that is characterized by inflammation of the lungs and central nervous system, and it is commonly associated with HIV/AIDS. Even though the disease accounts for roughly 15% of all AIDS-related deaths, it is relatively neglected. This is most especially true in Southern Africa which has the highest HIV/AIDS cases in the world and accounts for more than 10% of all HIV/AIDS cases worldwide most especially in Southern African countries such as Swaziland (Eswatini) which has the highest HIV/AIDS adult prevalence rate in the world. Despite this, there are little or no previous studies with regards to the epidemiological trends for cryptococcosis in Swaziland (Eswatini) which further suggests that it is relatively neglected. With the increasing spread of virulent strains of the fungus such as Cryptococcus gattii causing outbreaks in several countries around the world, it is important to have a concrete understanding of the epidemiological trends for cryptococcosis in Swaziland (Eswatini). This is also important during the current coronavirus outbreak as previous studies have reported higher morbidity and mortality rates among COVID-19 patients that are also co-infected with HIV/AIDS, cryptococcus as well as other secondary infections. This is further supported by the fact that Southern Africa has the highest number of COVID-19 cases in Africa as well as one of the highest in the world. As a result, the purpose of this study is to determine the epidemiological trends for cryptococcosis in Swaziland (Eswatini) as this will enable adequate control, management, assessment, policies, and regulations that will be useful during outbreaks. This will be achieved by performing a repeated cross-sectional study to determine the epidemiological changes and trends for cryptococcosis in Swaziland (Eswatini) over a 5-year period from 2023 to 2028.

EnTIRE: Mapping Normative Frameworks for EThics and Integrity of REsearch

Background: The areas of Research Ethics and Research Integrity (RE+RI) are rapidly evolving. In the EU and internationally, new legislation, codes of conduct and good practices are constantly being developed. New technologies (e.g. gene editing), complex statistical methods (e.g. biostatistics), pressure to publish and obtain grants, and growing emphasis on stakeholder driven science (e.g. public-private partnerships) increase the complexity of conducting science. In this complex and dynamic environment, researchers cannot easily identify the correct rules and best tools for responsible conduct of research. This also increasingly constitutes a challenge for RE+RI experts. Aim: Our aim is to create a platform that makes the normative framework governing RE+RI easily accessible, supports application in research and evaluation, and involves all stakeholders in a participatory way, thus achieving sustainability. The platform will foster uptake of ethical standards and responsible conduct of research, and ultimately support research excellence and strengthen society’s confidence in research and its findings. Vision: Our vision is that in order to make the normative framework governing RE+RI accessible, a dynamic online Wiki-platform, owned by the community of RE+RI stakeholders, is needed. The value of this platform will lie in the availability of practical information on how to comply with EU, national and discipline-specific RE+RI standards and legislation, including information on rules and procedures, educational materials, and illustrative cases and scenarios. Adopting open science (open source and open data) approaches, the platform will be easy to use, by applying novel techniques for data collection and comparison, enabling users to navigate quickly and intuitively to appropriate content. In order to keep the platform up-to-date and sustainable, it will be based upon active involvement of the RE+RI community, and will contribute to further development of this community by providing a podium for reflection and dialogue on RE+RI norms and practices. Objectives: EnTIRE’s work packages (WP) will: undertake an in-depth stakeholder consultation across EU countries exploring RE+RI experiences and practices in order to define the boundaries of data to be collected, and developing a mapping structure adapted to user needs (WP 2); assemble the relevant normative elements, including RE+RI rules and procedures, educational materials, and illustrative casuistry, and identify relevant institutions across EU countries (WP 3-5); develop a user-friendly Wiki-platform and online resources to foster and facilitate responsible research practices and to promote compliance amongst European researchers with RE+RI standards and pertinent legislation and regulations (WP 6); and foster further development of the RE+RI community, that will support the platform and be supported by it, will keep the information up-to-date, disseminate the project’s findings and develop innovative strategies for maintaining the platform and building relationships to relevant organisations for further dissemination, including sustainable funding (WP 7). Relevance to the work programme: The proposed project responds directly to the core requirement of call SwafS-16-2016 to ‘provide a dynamic mapping of the RE+RI normative framework which applies to scientific research conducted in the EU and beyond’. Our proposal does this by using a participatory approach, stimulating knowledge transfer regarding codes and regulations, resources and institutions, and cases, by applying innovative ICT solutions and open science approaches, and by further developing a community of active users, to enable sustainability after the end of the project.

Capacity-building as an instrument to foster the implementation of nature-based solutions

This article presents teaching and learning material from three strategically designed ReNature Horizon 2020 project training activities. A total of twelve presentations covering different aspects of NbS implementation are presented with this article. Additionally, this article also includes materials produced by learners, throughout their work within self-organised groups carried out during the Second ReNature Training School. This is the second article publishing teaching and learning material arising from the ReNature project.

Sedation-Led chEmotherapy Evades Pain (S.L.E.E.P.)

Chemotherapy and other invasive therapies are often limited by side effects, pain and negative experiences that can limit adherence to the therapy itself. Such negative components add to the patient's depressive state due to the disease. This research project proposes the use of deep sedation during chemotherapy sessions or other disabling therapies in the treatment of tumors or other severe diseases. The proposed protocol provides for an ad hoc hospitalization which could be during the night, during the day or limited to a few hours. Administration during sleep eliminates the memory and the negative impact the treatment has on the rest of the patient's daily life. This approach also agrees with the evidence of the circadian rhythm of cellular repair processes, which is greater at sunrise and sunset and linked to a good quantity and quality of sleep. In conclusion, this project aims to reduce the negative impact and increase the adherence to and efficacy of the therapy itself.

Dataset for Mosquitoes (Diptera: Culicidae) from Cross Key, Monroe County, Florida, USA

The Florida Keys Mosquito Control District deploys dry ice-baited light traps to monitor mosquito populations throughout the Florida Keys. Cross Key is an island directly north of Key Largo and via bridges it serves as a link between Key Largo and mainland Florida. This paper describes a data set compiled from trap collections on Cross Key, Florida, between September 23, 2002 and March 1, 2016.