USE OF GLUTAMINE AS AN ADJUVING THERAPY FOR THE NUTRITIONAL AND PHYSIOLOGICAL RESTORATION OF THE BIG BURNED PATIENT

Objective: To analyze the applicability of glutamine in the recovery of the nutritional and physiological status of burn patients. Methods: Study based on a literary review taken from reliable sources such as: The Scientific Electronic Library Online (Scielo), Pubmed, Bireme, Latin American and Caribbean Literature in Health Sciences (Lilacs), Virtual Health Library, the descriptors used were: glutamine ; nutritional therapy; burned; nutrition therapy; burned patients; glutamine, published in the last eleven years (2009-2020). Results: The research was carried out in a literary review format 30 full documents were read, 23 scientific articles were used, 3 bases of the Ministry of Health, 7 were postponed, the arguments used in the composition of the article, were the answer to the problem about applicability about the nutrient with immunomodulatory function glutamine for the recovery of the nutritional and physiological state of burn patients. Conclusion: The research argued about the use of glutamine in the treatment of large burn patients, through data obtained by literary analysis. The results obtained will contribute to the guidelines on the use of immunonutrients to improve the immune response, modulate the inflammatory response, reduce the rates of infectious complications, bringing a possible reduction in hospitalization costs. However, there is a need for further studies focused on this topic, in order to make the benefits of these immunonutrients appreciable for the scientific community, especially in terms of nutritional support more appropriate to supplementation and the recommendation of these nutrients.

SIGNS OF SUCETTABILITY ASSOCIATED WITH EXTRINSIC FACTORS TO FUNGAL INFECTION BY THE GENUS SPOROTHRIX SPP.

Objective: To evaluate the susceptibility to infection by the genus sporothrix spp.; targeting patients with immunosuppression due to the use of inadequate medication, seropositive patients (carriers of Human Immunodeficiency Syndrome – HIV) and alcoholics dependents. Method: This is an integrative review of the literature available in the PUBMED database, using the descriptors: “Sporotrichosis”, “Fungi” and “Sporothrix”, duly registered in MeSH, using the boolean operator AND. A total of 128 articles were found and evaluated and, at the end, 15 were selected to compose this review. The inclusion criteria were: full articles, available free of charge, published in English between 2010 and 2020. Results: Sporotrichosis is clinically characterized in fixed cutaneous, lymphocutaneous, disseminated cutaneous and extracutaneous. Frequently the appearance of disseminated cutaneous sporotrichosis occurs especially in immunosuppressed individuals. The four cases evaluated have as etiological agent in common, the genus Sporothrix spp., distinguishing the species, the contagion, clinical aspects and their susceptibility factors. Conclusion: However, most cases of sporotrichosis are related to a dysfunction of the immune system. As well, the unusual cases characterize a challenge to reliable diagnosis and can often lead to a wrong pharmacological therapy.

Aromatherapy: Prophylactic and Therapeutic Approach to Diseases of the Respiratory System

Infectious diseases are a significant public health challenge due to the increasing recognition of new infectious agents and the resurgence of infections until recently controlled. These infectious illnesses constitute many hospital admissions, mainly respiratory focus, which requires high-cost therapy. One of the strategies to prevent injuries leading to hospitalization is reducing the body’s inflammatory response. Thus, aromatherapy seems to be a useful adjuvant therapeutic tool due to the essential oils’ synergistic action with proven anti-inflammatory and antimicrobial properties. Hence, this study proposes an integrated review of the literature on aromatherapy as a tool to be used in prophylaxis and therapy in respiratory system disorders. After passing the criteria of exclusion and content analysis, a set of 124 articles narrowed to 44 articles that support the anti-inflammatory properties of the sesquiterpenes, such as the farnesol. This substance treats the respiratory system and is present in Cymbopogon nardus, Cymbopogon flexuosus, and Rosa damascena. Caryophyllene and its derivatives are present in Syzygium aromaticum, Rosmarinus officinalis, and Cannabis sativa. Besides, α-bisabolol and chamazulene present in Matricaria recutita and Achillea millefolium. Other oils have antibiotic properties that act against gram-positive and gram-negative bacterias according to their constitution’s complexity and interaction with these microorganisms. In this context, some species such as Cinnamomum zeylanicum, Citrus hystrix, Cymbopogon Citratus, Eucalyptus globulus, Eucalyptus odorata, Juniperus communis, Lavandula angustifólia, Lavandula intermedia, Melaleuca leucadendra, Mentha piperita, Pinus sylvestris, Syzygium aromaticum, and Thymus vulgaris are in the spotlight. Several studies, both in vitro and in vivo, have demonstrated the potential use of essential oils alone or combined with oils from other species as a strategy for the prevention of respiratory diseases and potentiation of standard therapies. This approach is possible due to the synergistic effects of substances with bioactive potential such as sesquiterpenes, monoterpenes, and phenylpropanoids.