The Visualization, Interaction and Simulation Laboratory (VISLab) is part of the Computer Graphics, Image Processing and Interaction research group, which started its activities in 1978 developing projects mainly on rendering and animation. Along the years, as new researchers joined the group, new research fields such as image acquisition and analysis, virtual reality, non-conventional interaction, and visualization of complex data started to be investigated. Within this group, VISLab is majorly concerned with research on human-computer interaction, with emphasis on non-conventional, 3D interaction and haptics, and immersive visualization in the context of virtual and augmented reality applications. In this paper, we present the research of the VISLab and the strategy being used to achieve its main goal: to enhance the human with computers, extending the perception capabilities and improving the human power of action in a natural way.