This chapter provides a mentoring roadmap for success in college life and when transitioning to the workplace. First-year students learn that a successful mentee is self-directed, knows what to look for in a mentor, uses skills to engage in effective mentoring, and recognizes there are various types of mentoring relationships. The authors describe what a first-year student should look for when seeking an effective mentor. Readers are shown the benefits for using a developmental mentoring network and for becoming self-directed learners and mentees. The chapter includes activities and exercises to develop critical skills in self-understanding, listening, help-seeking, problem solving, and goal setting to be applied in both academic and professional settings. When successful people receive an award or recognition, what they have in common is they did not make it alone – others guided and supported their learning, growth, and success.