scholarly journals The histology of the blood and the red bone-marrow of the leopard frog, Rana pipiens

1919 ◽  
Vol 25 (4) ◽  
pp. 436-480 ◽  
Author(s):  
H. E. Jordan
Keyword(s):  
Bone Marrow ◽  
Rana Pipiens ◽  
Leopard Frog ◽  
Red Bone Marrow

Dosimetry with 188Re-labelled monoclonal anti-CD66 antibodies

2006 ◽  
Vol 45 (03) ◽  
pp. 134-138 ◽  
Author(s):  
T. Kull ◽  
N. M. Blumstein ◽  
D. Bunjes ◽  
B. Neumaier ◽  
A. K. Buck ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Bone Marrow ◽  
Gamma Camera ◽  
Absorbed Dose ◽  
Correlation Coefficients ◽  
Residence Times ◽  
Reliable Prediction ◽  
Red Bone Marrow ◽  
Antibody Preparation ◽  
Simplified Method

SummaryAim: For the therapeutic application of radiopharmaceuticals the activity is determined on an individual basis. Here we investigated the accuracy for a simplified assessment of the residence times for a 188Re-labelled anti-CD66 monoclonal antibody. Patients, methods: For 49 patients with high risk leukaemia (24 men, 25 women, age: 44 ± 12 years) the residence times were determined for the injected 188Re-labelled anti-CD66 antibodies (1.3 ± 0.4 GBq, 5–7 GBq/mg protein, >95% 188Re bound to the antibody) based on 5 measurements (1.5, 3, 20, 26, and 44 h p.i.) using planar conjugate view gamma camera images (complete method). In a simplified method the residence times were calculated based on a single measurement 3 h p.i. Results: The residence times for kidneys, liver, red bone marrow, spleen and remainder of body for the complete method were 0.4 ± 0.2 h, 1.9 ± 0.8 h, 7.8 ± 2.1 h, 0.6 ± 0.3 h and 8.6 ± 2.1 h, respectively. For all organs a linear correlation exists between the residence times of the complete method and the simplified method with the slopes (correlation coefficients R > 0.89) of 0.89, 0.99, 1.23, 1.13 and 1.09 for kidneys, liver, red bone marrow, spleen and remainder of body, respectively. Conclusion: The proposed approach allows reliable prediction of biokinetics of 188Re-labelled anti-CD66 monoclonal antibody biodistribution with a single study. Efficient pretherapeutic estimation of organ absorbed dose may be possible, provided that a more stable anti-CD66 antibody preparation is available.

scholarly journals The ICRP recommended methods of red bone marrow dosimetry

2021 ◽  
pp. 106611
Author(s):  
Maria Zankl ◽  
Jonathan Eakins ◽  
José-María Gómez Ros ◽  
Christelle Huet
Keyword(s):  
Bone Marrow ◽  
Red Bone Marrow

Hopping and swimming in the leopard frog,Rana pipiens: I. Step cycles and kinematics

1996 ◽  
Vol 230 (1) ◽  
pp. 1-16 ◽  
Author(s):  
Susan E. Peters ◽  
Lynn T. Kamel ◽  
David P. Bashor
Keyword(s):  
Rana Pipiens ◽  
Leopard Frog

scholarly journals Redescription of the Frog Bladder Fluke Gorgoderina attenuata from the Northern Leopard Frog, Rana pipiens

2009 ◽  
Vol 95 (3) ◽  
pp. 665-668 ◽  
Author(s):  
Matthew G. Bolek ◽  
Scott D. Snyder ◽  
John Janovy
Keyword(s):  
Rana Pipiens ◽  
Leopard Frog ◽  
Northern Leopard Frog
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