Cognitive functions and quality of life in patients with low-grade gliomas: The impact of radiotherapy

1994 ◽  
Vol 36 (1) ◽  
pp. 48-54 ◽  
Author(s):  
M. J. B. Taphoorn ◽  
A. Klein Schiphorst ◽  
F. J. Snoek ◽  
J. Lindeboom ◽  
J. G. Wolbers ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cognitive Functions ◽  
Low Grade ◽  
Low Grade Gliomas ◽  
The Impact

Epilepsy in low-grade gliomas: The impact on cognitive function and quality of life

2003 ◽  
Vol 54 (4) ◽  
pp. 514-520 ◽  
Author(s):  
Martin Klein ◽  
Nadine H. J. Engelberts ◽  
Henk M. van der Ploeg ◽  
Dorotheé G. A. Kasteleijn-Nolst Trenité ◽  
Neil K. Aaronson ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cognitive Function ◽  
Low Grade ◽  
Low Grade Gliomas ◽  
The Impact

scholarly journals QOL-36. USE OF CANNABINOIDS IN THE PEDIATRIC CENTRAL NERVOUS SYSTEM TUMOR POPULATION

2020 ◽  
Vol 22 (Supplement_3) ◽  
pp. iii438-iii438
Author(s):  
Kathleen Dorris ◽  
Jessica Channell ◽  
Ashley Mettetal ◽  
Molly Hemenway ◽  
Natalie Briones ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Central Nervous System ◽  
Nervous System ◽  
Cell Activity ◽  
Cns Tumors ◽  
Low Grade ◽  
Tumor Type ◽  
Central Nervous System Tumor ◽  
The Impact

Abstract BACKGROUND Cannabinoids, including cannabidiol (CBD) and tetrahydrocannabinol (THC), are a class of compounds found in marijuana. Numerous studies in adults have examined cannabinoid use in management of cancer-related symptoms such as nausea, anorexia, and pain. Less is known about the use in the pediatric oncology population. METHODS A prospective observational study has been ongoing since 2016 at Children’s Hospital Colorado to evaluate cannabinoids’ impact using PedsQL™ modules on quality of life of pediatric patients with central nervous system (CNS) tumors who are 2–18 years old. Laboratory assessments of T-cell activity and pharmacokinetics of CBD, THC and associated metabolites are in process. Diaries with exploratory information on cannabinoid use patterns are being collected. RESULTS Thirty-three patients (14:19; male:female) have been enrolled with a median age of 6.4 years (range, 2.9–17.7 years). The most common tumor type in enrolled patients is embryonal tumors (13/33; 39%). Nine (27%) patients have low-grade glial/glioneuronal tumors, and eight (24%) had high-grade/diffuse midline gliomas. The remaining patients had ependymoma or craniopharyngioma. The median time on cannabinoids is 9 months. Most (n=20) patients have used oral products with CBD and THC. One patient continues on cannabinoid therapy in follow up. Preliminary immune function analyses identified impaired neutrophil superoxide anion production and chemotaxis in patients taking cannabinoids at early time points on therapy. CONCLUSIONS Families of children with various CNS tumors are pursuing cannabinoid therapy for both antitumor and supportive care purposes. Analysis of the impact of cannabinoids on patients’ quality of life is ongoing.

Low-grade gliomas in adults

2011 ◽  
pp. 1-18 ◽  
Author(s):  
Nader Sanai ◽  
Susan Chang ◽  
Mitchel S. Berger
Keyword(s):  
Quality Of Life ◽  
Molecular Markers ◽  
Diagnostic Imaging ◽  
Recent Literature ◽  
Low Grade ◽  
Operative Techniques ◽  
Comprehensive Review ◽  
Low Grade Gliomas ◽  
Adjuvant Therapies

In recent years, advances in the understanding of low-grade glioma (LGG) biology have driven new paradigms in molecular markers, diagnostic imaging, operative techniques and technologies, and adjuvant therapies. Taken together, these developments are collectively pushing the envelope toward improved quality of life and survival. In this article, the authors evaluate the recent literature to synthesize a comprehensive review of LGGs in the modern neurosurgical era.

scholarly journals Low Grade Gliomas in Eloquent Locations – Implications for Surgical Strategy, Survival and Long Term Quality of Life

PLoS ONE ◽  
2012 ◽  
Vol 7 (12) ◽  
pp. e51450 ◽  
Author(s):  
Asgeir S. Jakola ◽  
Geirmund Unsgård ◽  
Kristin S. Myrmel ◽  
Roar Kloster ◽  
Sverre H. Torp ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Surgical Strategy ◽  
Low Grade ◽  
Low Grade Gliomas

scholarly journals Evaluation of the impact of high-tone therapy on cognitive disorders and quality of life in the complex treatment of patients with comorbid pathology

2021 ◽  
pp. 345-351
Author(s):  
Iryna SHMAKOVA ◽  
Svitlana PANINA ◽  
Volodymyr MYKHAYLENKO
Keyword(s):  
Quality Of Life ◽  
Cognitive Functions ◽  
Anxiety And Depression ◽  
High Tone ◽  
Complex Treatment ◽  
Group I ◽  
Sf 36 ◽  
Group Ii ◽  
The Impact

Introduction. Comorbidity is an independent risk factor for mortality and significantly influences the prognosis and quality of life. Purpose: to evaluate the impact of high-tone HiTOP 4 touch therapy on cognitive disorders and quality of life in the complex treatment of patients with comorbid pathology. Methods: complex treatment of 2 groups of patients with inclusion in the basic treatment regimen of high-tone therapy was carried out - a total of 80 patients (men - 34, women - 46) aged 41 to 79 years old, group I - patients with hypertension and chronic cerebral ischemia (CСI) - 38 patients and group II - patients with hypertension, CСI and concomitant diabetes mellitus (DM) type 2 - 42 patients. The average age in group I was 61.5, in group II - 65.5. Group I received lisinopril and amlodipine in one tablet, group II received metformin in addition to the above therapy. Both groups received a course of 10 sessions of high-tone therapy using the device HiTOP 4 touch (Germany) according to the general method: 2 electrodes on the feet, 2 on the forearms and one on the neck-collar area. All the patients were assessed for their cognitive condition, degree of anxiety and depression, and estimated for quality of life before and after a course of high-tone therapy. In order to do this, we used valid assessment tests, such as the Montreal Cognitive Assessment Scale (MoCA), the Hospital Anxiety and Depression Scale (HADS), and the SF-36 Quality of Life Questionnaire. Results: the course of high-tone therapy for patients with hypertension and CCI led to improved quality of life, on all indicators of the SF-36 scale, except for pain intensity, increased cognitive functions by 3.52 points on the MoCA scale, reduced anxiety by 2.06 points and depression by 1.92 points on the HADS scale. The course of high-tone therapy for patients with CCI, hypertension and type 2 DM resulted in a significant improvement of 5 out of 8 quality of life indicators on the SF-36 scale, cognitive functions by 2.27 points on the MoCA scale and reduced anxiety by 4.3 points, and depression by 0.53 points on the HADS scale. Conclusion: the inclusion of high-tone therapy in the complex treatment of patients with comorbid pathology improves cognitive functions, reduces anxiety and depression, improves quality of life. Keywords: comorbid pathology, high-tone therapy, cognitive functions, anxiety, depression, quality of life,

scholarly journals Diagnostic assertiveness of cerebellar pilocytic astrocytoma in the pediatric age

2022 ◽  
Vol 10 (19) ◽  
pp. 41-47
Author(s):  
Ana L. Pichardo-Ávalos
Keyword(s):  
Quality Of Life ◽  
Pilocytic Astrocytoma ◽  
High Morbidity ◽  
Low Grade ◽  
Pediatric Age ◽  
Delay In Diagnosis ◽  
Tumor Lesion ◽  
The Cost ◽  
The Impact

Pilocytic astrocytoma of the cerebellum in the pediatric age is the most frequent benign tumor lesion of the nervous system in children according to the WHO. International literature mentions that being low-grade tumors they have a high curative capacity. If the entire tumor is resected, when it is completely removed, survival increases with a high quality of life for children who presented this pathology and was treated on time. However, the delay in diagnosis and therefore in its treatment could generate the possibility of tumor transformation, the malignant nature of the transformed injuries has a very high morbidity and mortality, without mentioning that the degree of cognitive sequelae greatly affects the quality of life of the survivors. That is why the training of pediatric and non-pediatric first contact doctors imply a great responsibility since it gives the population and patients suffering from this nosology the possibility to improve their future life, as well as reduce the cost of the impact caused by the injuries they suffer. On the other hand, these tumors can transform generating devastating prognoses, without taking into account the economic and social repercussions of patients suffering from a low-grade tumor. When it is detected and treated assertively in a timely manner, it offers them greater opportunities than those who did not have such a timely diagnosis.

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