scholarly journals Does family history of cancer modify the effects of lifestyle risk factors on esophageal cancer? a population-based case-control study in China

2010 ◽  
Vol 128 (9) ◽  
pp. 2147-2157 ◽  
Author(s):  
Ming Wu ◽  
Zuo-Feng Zhang ◽  
Ellen Kampman ◽  
Jin-Yi Zhou ◽  
Ren-Qiang Han ◽  
...  
2021 ◽  
Vol 26 (1) ◽  
Author(s):  
Arisara Poosari ◽  
Thitima Nutravong ◽  
Prakasit Sa-ngiamwibool ◽  
Wises Namwat ◽  
Supaporn Chatrchaiwiwatana ◽  
...  

Abstract Background Previous studies have shown the association between Campylobacter species infection and that environmental factors, poor oral hygiene in particular, are linked to an increased risk of esophageal cancer (EC). However, no study has reported on these factors in Thailand. Thus, this study’s objective was to evaluate the impact of the relationship between Campylobacter infection and environmental factors on EC incidence in the population of Thailand. Methods Data from a case–control study were collected from 105 newly diagnosed EC cases and 105 controls recruited from 2007 to 2017. Infection with Campylobacter spp. was detected in the formalin-fixed paraffin-embedded (FFPE) tissue of EC taken from gastroesophageal biopsy specimens obtained from the participants, and evaluated using TaqMan® real-time PCR. Multivariable logistic regression was performed to calculate the odds ratios (ORs) and perform data analysis. Results Smoking, alcohol use, a family history of cancer, history of gastroesophageal reflux disease, poor oral hygiene and Campylobacter spp. infection were shown to be significant risk factors for EC (p  <  0.05). The combination of poor oral hygiene and infection with Campylobacter spp. constituted significant risk for EC (p  <  0.001). In addition, the risk of EC in subjects co-infected with C. rectus and C. concisus that practiced poor oral hygiene was even higher and was significant (ORadj  =  4.7; 95% CI 2.41–9.98; p  =  0.003). Conclusions In Thailand, the major risk factors for EC are smoking status, alcohol drinking, family history of cancer, GERD, poor oral hygiene and Campylobacter spp. infection. This study found Campylobacter spp. prevalence to be associated with EC and appears to be enhanced by poor oral hygiene, suggesting that a combination of poor oral hygiene and Campylobacter species infection may together act as an important etiological risk factor for EC.


PLoS ONE ◽  
2017 ◽  
Vol 12 (2) ◽  
pp. e0171709 ◽  
Author(s):  
Geffen Kleinstern ◽  
Rania Abu Seir ◽  
Riki Perlman ◽  
Areej Khatib ◽  
Ziad Abdeen ◽  
...  

1997 ◽  
Vol 119 (2) ◽  
pp. 231-235 ◽  
Author(s):  
W. CAO ◽  
C. P. B. VAN DER PLOEG ◽  
J. XU ◽  
C. GAO ◽  
L. GE ◽  
...  

A population-based case-control study to determine social and behavioural risk factors for Taenia solium cysticercosis in humans was carried out in a rural area, Shandong province, China. Forty-eight cases with cysticercosis were ascertained through a prevalence survey conducted among 7281 persons in 1993. For each case, four controls residing in the same village and matched for age and sex were randomly selected. Information regarding demographic, social and behavioural factors was collected during house visits through interviews and direct observation. Risk factors strongly associated with human cysticercosis included poor personal hygiene, being unable to recognize cysticerci-containing meat, poor pig-raising practices and a history of passing tapeworm proglottides. The results indicate that health education in combination with chemotherapy for taeniasis is required for the control of cysticercosis in humans.


The Prostate ◽  
1989 ◽  
Vol 14 (2) ◽  
pp. 117-122 ◽  
Author(s):  
Kenji Oishi ◽  
Kenichiro Okada ◽  
Osamu Yoshida ◽  
Hirohiko Yamabe ◽  
Yoshiyuki Ohno ◽  
...  

2007 ◽  
Vol 16 (5) ◽  
pp. 466-470 ◽  
Author(s):  
Mahaut Ripert ◽  
Florence Menegaux ◽  
Yves Perel ◽  
Françoise Méchinaud ◽  
Emmanuel Plouvier ◽  
...  

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