Surgical treatment of carcinoma of the breast, v. changes in patient population and therapeutic modalities at a metropolitan hospital (1971–1980)

1985 ◽  
Vol 29 (3) ◽  
pp. 147-153
Author(s):  
Yeu-Tsu N. (Margaret) Lee
Keyword(s):  
Surgical Treatment ◽  
Patient Population ◽  
Carcinoma Of The Breast ◽  
Therapeutic Modalities ◽  
Metropolitan Hospital

Different Therapeutic Approaches and Outcome in the Treatment of Pterygium

1998 ◽  
Vol 8 (3) ◽  
pp. 148-152 ◽  
Author(s):  
C. H. Karabatsas ◽  
G. W. Marsh ◽  
A. M. Cook ◽  
S. D. Cook
Keyword(s):  
Surgical Treatment ◽  
Surgical Techniques ◽  
Surgical Excision ◽  
Lamellar Keratoplasty ◽  
Therapeutic Approaches ◽  
Therapeutic Modalities ◽  
Results Of Treatment ◽  
One Year

Purpose This study was initiated to investigate the role of different therapeutic modalities in the outcome of the surgical treatment of pterygium. Methods The results of treatment of pterygia with a variety of surgical techniques were studied in 56 eyes (49 patients) operated on at Bristol Eye Hospital during a period of five years. The surgical techniques included simple excision; bare sclera; conjunctival autograft; sliding conjunctival flap; lamellar keratoplasty and penetrating keratoplasty. Twelve eyes received additional beta irradiation in a fractionated total dose of 40 Gys. Results The incidence of recurrence was 23.2% for the 43 treated primary pterygia, and 23% for the 13 recurrent pterygia. All recurrences occurred between 2.5 and 11 months postoperatively. None of the 11 cases where additional beta irradiation was used showed any recurrence or other complication within the study period. In the recurrent pterygia group, the cases treated with a combination of surgical excision and beta irradiation, showed significantly lower recurrence rate (p<0.001) compared to those cases treated with surgical excision alone. Conclusions Beta irradiation as a complement to surgical treatment of pterygium, is successful in treating high risk cases such as reoperations, whereas for the majority of primary pterygia surgical excision alone is adequate. Additionally, follow up of one year will reveal any recurrences.

scholarly journals Surgical Treatment for Leptomeningeal Disease

2017 ◽  
Vol 24 (1) ◽  
pp. 47-53 ◽  
Author(s):  
Andrey A. Volkov ◽  
Andreas K. Filis ◽  
Frank D. Vrionis
Keyword(s):  
Surgical Treatment ◽  
Surgical Complications ◽  
Patient Population ◽  
Leptomeningeal Carcinomatosis ◽  
Intrathecal Chemotherapy ◽  
Chemotherapeutic Agents ◽  
Treatment Modalities ◽  
Leptomeningeal Disease ◽  
Multimodal Approach ◽  
Intracerebral Pressure

Background Advancements in cancer treatment have led to more cases of leptomeningeal disease, which requires a multimodal approach. Methods Treatment modalities are reviewed from a neurosurgical standpoint, focusing on intrathecal chemotherapy and shunting devices. Potential complications and how to avoid them are discussed. Results The Ommaya reservoir and the chemoport are used for administering intrathecal chemotherapy. Use of ventriculo-lumbar perfusion can efficiently deliver chemotherapeutic agents and improve intracerebral pressure. Shunting systems, in conjunction with all of their variations, address the challenge of hydrocephalus in leptomeningeal carcinomatosis. Misplaced catheters, malfunction of the system, and shunt-related infections are known complications of treatment. Conclusions From an oncological perspective, the surgical treatment for leptomeningeal disease is limited; however, neurosurgery can be used to aid in the administration of chemotherapy and address the issue of hydrocephalus. Minimizing surgical complications is important in this sensitive patient population.

Efficacy of Amikacin in Septic Abortion: Serum and Urine Antibiotic Concentrations

1976 ◽  
Vol 4 (4) ◽  
pp. 223-227
Author(s):  
Jorge Bravo-Sandoval ◽  
Gonzalo Cinco-Espinoza ◽  
Donato Ramírez-López ◽  
Enrique Becerra-Muñoz ◽  
Emma Galindo-Hernández ◽  
...  
Keyword(s):  
Cell Wall ◽  
Surgical Treatment ◽  
Maternal Death ◽  
Patient Population ◽  
Great Majority ◽  
Tissue Hypoxia ◽  
Uterine Curettage ◽  
Septic Abortion ◽  
Serum And Urine

Septic abortion is a frequent cause of maternal death in our patient population. The great majority of bacteria isolated were enterobacteria. Since antibiotics capable of destroying the cell wall release endotoxins (producing vasoconstriction and tissue hypoxia) antibiotics which do not destroy bacteria like amikacin are preferred. Amikacin, 500 mg intramuscularly every twelve hours, was used concomitantly with uterine curettage and fluid and electrolyte restoration in thirty septic abortion patients. All the patients responded, obviating the need for more heroic surgical treatment such as hysterectomy. Previously used antibiotics have not been as effective in our patient population.

Management of life-threatening aortoesophageal fistula: experiences learned from eight patients

2020 ◽  
pp. 028418512093322
Author(s):  
Chengshi Chen ◽  
Jong Woo Kim ◽  
Ji Hoon Shin ◽  
Yohan Kwon ◽  
Jinoo Kim ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Rapid Identification ◽  
Massive Hemorrhage ◽  
Aortoesophageal Fistula ◽  
Therapeutic Modalities ◽  
Endovascular Interventions ◽  
Aortic Repair ◽  
Life Threatening ◽  
Timely Fashion ◽  
Age Range

Background Aortoesophageal fistula (AEF) is a rare but fatal condition causing massive upper gastrointestinal bleeding. Purpose To report our experiences in the management of life-threatening AEF. Material and Methods A total of eight patients (seven men, one woman; mean age = 59.4 years; age range = 43‒76 years) presenting with AEF between 2005 and 2018 were recruited from three different Korean hospitals. The medical records of these patients were reviewed for patient demographics, clinical features, diagnostic and therapeutic modalities, and outcomes. Results Two patients died as a result of massive hemorrhage before endovascular or surgical treatment could be undertaken. Of the six patients who were treated, five underwent endovascular interventions: embolization of the fistula using n-butyl cyanoacrylate (NBCA) and subsequent thoracic endovascular aortic repair (TEVAR) in two patients; TEVAR alone in two patients; and NBCA embolization alone in one patient. Among them, three patients who received TEVAR with or without NBCA embolization in a timely fashion recovered and were discharged. One patient who received delayed TEVAR died of disseminated intravascular coagulation, and one who received NBCA embolization alone died of hemorrhagic shock, both dying within three days of treatment. The remaining patient who underwent surgical aortic repair is alive after 13 years. Conclusion Rapid identification and surgical treatment are necessary to increase the likelihood of survival, if emergency surgery is feasible. TEVAR in a timely fashion facilitates hemodynamic stabilization by rapidly controlling hemorrhage and saves the patient’s life.

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