Determination of the thiol redox state of organisms: new oxidative stress indicators

2004 ◽  
Vol 378 (7) ◽  
pp. 1783-1792 ◽  
Author(s):  
Nikolaos Patsoukis ◽  
Christos D. Georgiou
Keyword(s):  
Oxidative Stress ◽  
Redox State ◽  
Stress Indicators ◽  
Thiol Redox State ◽  
Thiol Redox ◽  
Oxidative Stress Indicators

Fluorometric determination of thiol redox state

2005 ◽  
Vol 383 (6) ◽  
pp. 923-929 ◽  
Author(s):  
Nikolaos Patsoukis ◽  
Christos D. Georgiou
Keyword(s):  
Redox State ◽  
Fluorometric Determination ◽  
Thiol Redox State ◽  
Thiol Redox

Thiol redox state and oxidative stress in midbrain and striatum of weaver mutant mice, a genetic model of nigrostriatal dopamine deficiency

2005 ◽  
Vol 376 (1) ◽  
pp. 24-28 ◽  
Author(s):  
Nikolaos Patsoukis ◽  
Ioannis Papapostolou ◽  
George Zervoudakis ◽  
Christos D. Georgiou ◽  
Nikolaos A. Matsokis ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Redox State ◽  
Genetic Model ◽  
Mutant Mice ◽  
Thiol Redox State ◽  
Nigrostriatal Dopamine ◽  
Thiol Redox ◽  
And Oxidative Stress

Multiparametric protocol for the determination of thiol redox state in living matter

2014 ◽  
Vol 74 ◽  
pp. 85-98 ◽  
Author(s):  
Konstantinos Grintzalis ◽  
Ioannis Papapostolou ◽  
Dimitris Zisimopoulos ◽  
Irene Stamatiou ◽  
Christos D. Georgiou
Keyword(s):  
Redox State ◽  
Living Matter ◽  
Thiol Redox State ◽  
Thiol Redox

Differentiation of Sclerotinia minor depends on thiol redox state and oxidative stress

2008 ◽  
Vol 54 (1) ◽  
pp. 28-36 ◽  
Author(s):  
Nikolaos Patsoukis ◽  
Christos D. Georgiou
Keyword(s):  
Oxidative Stress ◽  
Redox State ◽  
Phytopathogenic Fungus ◽  
Sclerotinia Minor ◽  
Thiol Redox State ◽  
Sh Group ◽  
Thiol Redox ◽  
Sclerotial Differentiation ◽  
And Oxidative Stress

Sclerotial differentiation in Sclerotinia minor is associated with oxidative stress and thiol redox state. The significance of oxidative stress to sclerotial differentiation was revealed by the higher oxidative stress of S. minor compared with a nonsclerotiogenic counterpart. The effect of thiol redox state on sclerotial differentiation was shown by the antioxidant action of the thiol (-SH) group of N-acetylcysteine and cysteine and by an unknown (not antioxidant) role of glutathione (GSH) on S. minor. The nonantioxidant role of GSH was indicated by the differentiation-inhibiting and differentiation-noninhibiting actions of the GSH biosynthesis inhibitor l-buthionine-S,R-sulfoximine and the GSH biosynthesis inducer l-2-oxo-thiazolidine-4-carboxylate, respectively, and by the increase of oxidative stress they caused during the transition from the undifferentiated to differentiated state of S. minor. Moreover, N-acetylcysteine can be used as a potent nontoxic fungicide against this phytopathogenic fungus by acting as a growth-inhibiting cytotoxic oxidant and by sustaining the fungus in the undifferentiated hyphal stage, which is vulnerable to degradation by soil microorganisms.

Thiol redox state (TRS) and oxidative stress in the mouse hippocampus after pentylenetetrazol-induced epileptic seizure

2004 ◽  
Vol 357 (2) ◽  
pp. 83-86 ◽  
Author(s):  
Nikolaos Patsoukis ◽  
George Zervoudakis ◽  
Nikolaos T Panagopoulos ◽  
Christos D Georgiou ◽  
Fevronia Angelatou ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Epileptic Seizure ◽  
Redox State ◽  
Thiol Redox State ◽  
Mouse Hippocampus ◽  
Thiol Redox ◽  
And Oxidative Stress
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