An in situ silicone–silicone interpenetrating polymer network (IPN) with higher mechanical property, higher hydrophilicity, and lower protein adsorption

2018 ◽  
Vol 53 (12) ◽  
pp. 9325-9339 ◽  
Author(s):  
Yang Xie ◽  
Li Wang ◽  
Yan Zhang ◽  
Houbin Li ◽  
Ronghua Huang
Keyword(s):  
Mechanical Property ◽  
Protein Adsorption ◽  
Polymer Network ◽  
Interpenetrating Polymer Network ◽  
Lower Protein

In situ formation of interpenetrating polymer network using sequential thermal and click crosslinking for enhanced retention of transplanted cells

Biomaterials ◽  
2018 ◽  
Vol 170 ◽  
pp. 12-25 ◽  
Author(s):  
Hamid Sadeghi Abandansari ◽  
Mohammad Hossein Ghanian ◽  
Fahimeh Varzideh ◽  
Elena Mahmoudi ◽  
Sarah Rajabi ◽  
...  
Keyword(s):  
Polymer Network ◽  
Interpenetrating Polymer Network ◽  
In Situ Formation

scholarly journals Simultaneous Interpenetrating Polymer Network of Collagen and Hyaluronic Acid as an In Situ-Forming Corneal Defect Filler

2020 ◽  
Vol 32 (12) ◽  
pp. 5208-5216 ◽  
Author(s):  
Fang Chen ◽  
Peter Le ◽  
Krystal Lai ◽  
Gabriella M. Fernandes-Cunha ◽  
David Myung
Keyword(s):  
Hyaluronic Acid ◽  
Polymer Network ◽  
Interpenetrating Polymer Network ◽  
In Situ Forming

scholarly journals ENZYMATICALLY SYNTHESIZED pH-RESPONSIVE IPN FOR IN-SITU RELEASE OF PANTOPRAZOLE SODIUM

2019 ◽  
pp. 98-103
Author(s):  
Saruchi Sharma ◽  
VANEET KUMAR
Keyword(s):  
Drug Release ◽  
Polymer Network ◽  
Lateral Diffusion ◽  
Ph Sensitive ◽  
Interpenetrating Polymer Network ◽  
Release Behavior ◽  
Ph Responsive ◽  
Gum Tragacanth ◽  
Swelling Capacity

Objective: This study involves the synthesis of Gum tragacanth (gt) based interpenetrating polymer network (ipn) and its utilization for sustained release of anti-ulcerative drug i.e. pantoprazole sodium. Methods: IPN was synthesized from Gum tragacanth, polyacrylic acid (gt-cl-paa) hydrogel. gt-cl-paa was kept in distilled water. Further, acryamide (aam) and methylmethacrylate (mma) was added and then kept for overnight. Later on, lipase and glutaraldehyde were added. Homopolymers and the unreacted monomers were removed using acetone. Synthesized IPN was dried at 50 °C for further study. Synthesized ipn was swelled in water and the drug was added to it. The drug was entrapped in the pores of the synthesized ipn and then drug release behavior was studied using uv-vis spectrophotometer. Results: Gt, paa and mma based crosslinked IPN were synthesized using lipase-glutaraldehyde as initiator-crosslinker system. The synthesized IPN was pH sensitive and possessed the desired swelling capacity required for the controlled and systematic liberation of pantoprazole sodium at 37 °C. The kinetic of drug release was studied and found that lateral diffusion (DL) of drug was higher as compared to the initial diffusion (DI). The prepared IPN can be used as prospective carrier for prolonged drug delivery. Conclusion: A novel pH sensitive and colon targeted IPN was synthesized. It acts as an effective device for the controlled release of drug pantoprazole sodium.

Preparation and Properties of Oxidized Coal/Polyaniline Composite Material

2011 ◽  
Vol 306-307 ◽  
pp. 220-223
Author(s):  
Xiao Ping Fan ◽  
An Ning Zhou
Keyword(s):  
Composite Material ◽  
In Situ Polymerization ◽  
Polymer Network ◽  
Interpenetrating Polymer Network ◽  
Hydroxyl Groups ◽  
Oxidized Coal ◽  
Pani Composite ◽  
Maximum Conductivity ◽  
Hydrolysis Of

Semi-interpenetrating polymer network of coal/polyaniline (PANI) composite material were prepared by in situ polymerization. Raw coal was oxidized in different conditions by H2O2 and HNO3, respectively. The total acidic groups analysis, Fourier transform infrared (FTIR) spectrum, and conductivity test of the raw coal and the oxidized coal/PANI composite material were conducted. The results showed that the increases of the carboxyl groups and the hydroxyl groups were mainly attributed to the hydrolysis of the weak ether link and the transform from the carboxylate to carboxylic acid. These increases were benefit to the reaction of coal and PANI, and consequently enhanced the conductivity of the composite material. The maximum conductivity of oxidized coal/PANI reached 4.72×10‑1 S/cm.

Optimal response surface design of Gum tragacanth-based poly[(acrylic acid)-co-acrylamide] IPN hydrogel for the controlled release of the antihypertensive drug losartan potassium

RSC Advances ◽  
2014 ◽  
Vol 4 (75) ◽  
pp. 39822-39829 ◽  
Author(s):  
Saruchi Saruchi ◽  
B. S. Kaith ◽  
Rajeev Jindal ◽  
Vaneet Kumar ◽  
Manpreet S. Bhatti
Keyword(s):  
Controlled Release ◽  
Acrylic Acid ◽  
Polymer Network ◽  
Interpenetrating Polymer Network ◽  
Losartan Potassium ◽  
Surface Design ◽  
Gum Tragacanth ◽  
Ph Conditions ◽  
Poly Acrylic Acid

The present study proposes the development and optimization of a new interpenetrating polymer network (IPN), consisting of Gum tragacanth, poly(acrylic acid) (PAA), and poly(acrylamide) (PAAm), for the in situ controlled release of losartan potassium under different pH conditions at 37 °C.

Energetic interpenetrating polymer network (EIPN): enhanced thermo-mechanical properties of NCO-fMWCNTs/HTPB PU and alkyne-fMWCNTs/acyl-GAP based nanocomposite and its propellants

RSC Advances ◽  
2016 ◽  
Vol 6 (54) ◽  
pp. 49101-49112 ◽  
Author(s):  
Abbas Tanver ◽  
Mu-Hua Huang ◽  
Yunjun Luo
Keyword(s):  
Mechanical Properties ◽  
Polymer Network ◽  
Interpenetrating Polymer Network

Novel energetic interpenetrating polymer network (EIPN) nanocomposite comprised of fMWCNTs covalently attached to HTPB and GAP by facile in situ polymerization technique.

Anticorrosive Properties of Epoxy/Polyurethane IPNs Coatings Modified by Organic Montmorillonite

2011 ◽  
Vol 675-677 ◽  
pp. 481-484 ◽  
Author(s):  
Shao Yun Shan ◽  
Qing Ming Jia ◽  
Li Hong Jiang ◽  
Ya Ming Wang
Keyword(s):  
Polymer Network ◽  
Electrochemical Analysis ◽  
Interpenetrating Polymer Network ◽  
Cross Linking ◽  
Tem Analysis ◽  
Organic Montmorillonite ◽  
Matrix Microstructure ◽  
Intercalative Polymerization

Epoxy/polyurethane interpenetrating polymer network coatings(EP/PU IPNs) modified by organic montmorillonite(oMMT)were prepared by interpenetrating polymer technology and in situ intercalative polymerization methods. TEM analysis showed that there is interaction between the oMMT and EP, PU phase, and the oMMT plays a role of "cross-linking point", changing the EP/PU matrix microstructure. Electrochemical analysis showed that oMMT and IPNs of EP and PU exhibits synergistic effect on improving anticorrosive properties of pure EP. When PU content is 30%, oMMT content is 3%, the EP/PU IPNs coatings has the best corrosion resistance.

scholarly journals Porous scaffolds with the structure of an interpenetrating polymer network made by gelatin methacrylated nanoparticle-stabilized high internal phase emulsion polymerization targeted for tissue engineering

RSC Advances ◽  
2021 ◽  
Vol 11 (37) ◽  
pp. 22544-22555
Author(s):  
Atefeh Safaei-Yaraziz ◽  
Shiva Akbari-Birgani ◽  
Nasser Nikfarjam
Keyword(s):  
Tissue Engineering ◽  
Extracellular Matrix ◽  
Cell Growth ◽  
Polymer Network ◽  
Synthetic Polymers ◽  
Tissue Scaffolds ◽  
Interpenetrating Polymer Network ◽  
Porous Scaffolds ◽  
Promising Strategy ◽  
Internal Phase

The interlacing of biopolymers and synthetic polymers is a promising strategy to fabricate hydrogel-based tissue scaffolds to biomimic a natural extracellular matrix for cell growth.

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