The QTL controlling amino acid content in grains of rice (Oryza sativa) are co-localized with the regions involved in the amino acid metabolism pathway

2007 ◽  
Vol 21 (1) ◽  
pp. 127-137 ◽  
Author(s):  
Lingqiang Wang ◽  
Ming Zhong ◽  
Xianghua Li ◽  
Dejun Yuan ◽  
Yunbi Xu ◽  
...  
Keyword(s):  
Oryza Sativa ◽  
Amino Acid ◽  
Acid Content ◽  
Amino Acid Metabolism ◽  
Acid Metabolism ◽  
Amino Acid Content ◽  
Metabolism Pathway

scholarly journals Metabolome and exposome profiling of the biospecimens from COVID-19 patients in India

2021 ◽  
Vol 98 (4) ◽  
pp. 397-415
Author(s):  
Sh. Aggarwal ◽  
Sh. Parihari ◽  
A. Banerjee ◽  
J. Roy ◽  
N. Banerjee ◽  
...  
Keyword(s):  
Amino Acid ◽  
Amino Acid Metabolism ◽  
Indian Population ◽  
Acid Metabolism ◽  
Clinical Applications ◽  
Rapid Diagnosis ◽  
Plasma Samples ◽  
Metabolism Pathway ◽  
Diagnosis And Prognosis ◽  
Metabolome Profiling

Introduction. COVID-19 has become a global impediment by bringing everything to a halt starting from January 2020. India underwent the lockdown starting from 22nd March 2020 with the sudden spike in the number of COVID-19 patients in major cities and states. This study focused on how metabolites play a crucial role in SARSCoV-2 prognosis.Materials and methods. Metabolome profiling of 106 plasma samples and 24 swab samples from symptomatic patients in the Indian population of the Mumbai region was done. COVID-19 positive samples were further segregated under the non-severe COVID-19 and severe COVID-19 patient cohort for both plasma and swab.Results. After analyzing the raw files, total 7,949 and 12,871 metabolites in plasma and swab were found. 11 and 35 significantly altered metabolites were found in COVID-19 positive compared to COVID-19 negative plasma and swab samples, respectively. Also, 9 and 23 significantly altered metabolites were found in severe COVID-19 positive to non-severe COVID-19 positive plasma and swab samples, respectively. The majorly affected pathways in COVID-19 patients were found to be the amino acid metabolism pathway, sphingosine metabolism pathway, and bile salt metabolism pathway.Conclusion. This study facilitates identification of potential metabolite-based biomarker candidates for rapid diagnosis and prognosis for clinical applications.

scholarly journals Effects of nitrogen levels on gene expression and amino acid metabolism in Welsh onion

BMC Genomics ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Chen Zhao ◽  
Guanchu Ma ◽  
Lin Zhou ◽  
Song Zhang ◽  
Le Su ◽  
...  
Keyword(s):  
Gene Expression ◽  
Amino Acids ◽  
Amino Acid ◽  
Amino Acid Metabolism ◽  
Acid Metabolism ◽  
Protein Biosynthesis ◽  
Amino Acid Content ◽  
Growth And Yield ◽  
Welsh Onion ◽  
Amino Acid Synthesis

Abstract Background Welsh onion constitutes an important crop due to its benefits in traditional medicine. Nitrogen is an important nutrient for plant growth and yield; however, little is known about its influence on the mechanisms of Welsh onion regulation genes. In this study, we introduced a gene expression and amino acid analysis of Welsh onion treated with different concentrations of nitrogen (N0, N1, and N2 at 0 kg/ha, 130 kg/ha, and 260 kg/ha, respectively). Results Approximately 1,665 genes were differentially regulated with different concentrations of nitrogen. Gene ontology enrichment analysis revealed that the genes involved in metabolic processes, protein biosynthesis, and transportation of amino acids were highly represented. KEGG analysis indicated that the pathways were related to amino acid metabolism, cysteine, beta-alanine, arginine, proline, and glutathione. Differential gene expression in response to varying nitrogen concentrations resulted in different amino acid content. A close relationship between gene expression and the content of amino acids was observed. Conclusions This work examined the effects of nitrogen on gene expression and amino acid synthesis and provides important evidence on the efficient use of nitrogen in Welsh onion.

Amino acid content of chronic undercut cortex of the cat in reletion to electrical afterdisctrarge: comparison with cobalt epileptogenic lesions

1977 ◽  
Vol 55 (3) ◽  
pp. 523-536 ◽  
Author(s):  
I. Koyama ◽  
H. Jasper
Keyword(s):  
Cerebral Cortex ◽  
Electrical Stimulation ◽  
Amino Acid ◽  
Glutamic Acid ◽  
Aspartic Acid ◽  
Amino Acid Metabolism ◽  
Acid Metabolism ◽  
Amino Acid Content ◽  
Opposite Hemisphere ◽  
Afterdischarge Threshold

Chronic undercutting of cerebral cortex in the cat for survival periods of 9 to 308 days was found to cause an increase in duration of epileptiform electrical, afterdischarge and a significant decrease in content of glutamic acid, GABA, and aspartic acid as compared with homologous cortex of opposite hemisphere. These changes were comparable (though less marked) with changes previously found in cobalt-induced experimental epileptogenic lesions. Rate of release of GABA, glutamic acid, and aspartic acid into superfusates of undercut cortex at rest was higher in undercut cortex and was increased further by electrical stimulation. It was concluded that chronic partial denervation of cerebral cortex causes prolonged changes in metabolism or storage of glutamic acid, GABA, and aspartic acid probably related to increased tendency to prolonged epileptiform discharge similar in some respects (though not all) to changes observed in cobalt-induced cortical epileptogenic lesions. However, electrical afterdischarge threshold was not reduced in chronically undercut cortex and prolonged afterdischarge was not necessarily related to concentration of GABA in superfusate from undercut cortex, suggesting that factors other than amino acid metabolism may be also involved in mechanisms of epileptogenesis in undercut cortex.

scholarly journals Increased Grain Amino Acid Content in Rice with Earthworm Castings

2019 ◽  
Vol 9 (6) ◽  
pp. 1090 ◽  
Author(s):  
Min Huang ◽  
Chunrong Zhao ◽  
Yingbin Zou
Keyword(s):  
Amino Acid ◽  
Acid Content ◽  
Nutritional Value ◽  
Acid Metabolism ◽  
Amino Acid Content ◽  
Total Amino Acid ◽  
N Content ◽  
Total N ◽  
Rice Grains ◽  
Total Amino Acid Content

Enhancing the nutritional value of rice can improve the health of rice consumers. Grain amino acid content is an important nutritional component. This study was conducted to test the hypothesis that the application of earthworm castings could increase the grain amino acid content in rice. Results showed that total amino acid content in the grain of rice was significantly elevated by applying earthworm castings (17 kg m−2), with an average increase of 8% across four tested rice cultivars. Application of earthworm castings had no significant effect on total nitrogen (N) content but significantly increased the ratio of amino acid to N (total amino acid content/total N content) in rice grains. The results of the present study suggest that application of earthworm castings can increase grain amino acid content in rice by improving the efficiency of the N to amino acid conversion, and highlight that further studies are required to assess the effects of earthworm castings on the amino acid metabolism in rice grains.

scholarly journals Physiological Processes Contributing to the Difference in Grain Amino Acid Content between Two Hybrid Rice (Oryza sativa L.) Cultivars

Phyton ◽  
2019 ◽  
Vol 88 (2) ◽  
pp. 101-107
Author(s):  
Min Huang ◽  
Hengdong Zhang ◽  
Chunrong Zhao ◽  
Guanghui Chen ◽  
Yingbin Zou
Keyword(s):  
Oryza Sativa ◽  
Amino Acid ◽  
Acid Content ◽  
Hybrid Rice ◽  
Oryza Sativa L ◽  
Amino Acid Content ◽  
Physiological Processes ◽  
The Difference ◽  
Two Hybrid

Selenate mitigates arsenite toxicity in rice (Oryza sativa L.) by reducing arsenic uptake and ameliorates amino acid content and thiol metabolism

2016 ◽  
Vol 133 ◽  
pp. 350-359 ◽  
Author(s):  
Amit Kumar ◽  
Garima Dixit ◽  
Amit Pal Singh ◽  
Sanjay Dwivedi ◽  
Sudhakar Srivastava ◽  
...  
Keyword(s):  
Oryza Sativa ◽  
Amino Acid ◽  
Acid Content ◽  
Oryza Sativa L ◽  
Amino Acid Content ◽  
Arsenic Uptake ◽  
Thiol Metabolism

THE ACTIVITY OF ENZYMES OF AMINO ACID METABOLISM OF THE PLACENTA IN DIFFERENT TERMS OF THE PHYSIOLOGICAL AND COMPLICATED PREGNANCY

2019 ◽  
Vol 64 (5) ◽  
pp. 260-264
Author(s):  
Tatyana Nikolaevna Pogorelova ◽  
V. O. Gunko ◽  
A. A. Mikhelson ◽  
A. A. Nikashina ◽  
A. F. Mikhelson ◽  
...  
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Amino Acid Metabolism ◽  
Acid Metabolism ◽  
Amino Acid Content ◽  
Exchange Chromatography ◽  
Glutathione Synthetase ◽  
Spectrophotometric Methods ◽  
Metabolism Enzymes ◽  
Complicated Pregnancy

The activity of amino acid metabolism enzymes and the content of free amino acids in the placenta during physiological pregnancy and placental insufficiency (PI) were studied using spectrophotometric methods and ion-exchange chromatography. It was found that in PI placental activity of the studied enzymes: alanine-, cysteine-e, tyrosine-, glutamino- transferase, glutathione synthetase, glutamate dehydrogenase decreases at different periods of gestation. The opposite variations occur for aspartataminotranferase and glutaminase. Similar changes are detected for amino acids synthesized or used in the course of appropriate reactions: aspartic acid, glutamic acid, glutamine, alanine, cysteine, tyrosine, arginine. The correlation between enzyme activity and amino acid content was revealed. Different periods of pregnancy are characterized by varying degrees of change, especially expressed in the second trimester, characterized by the most intense growth and development of the fetus, and its increased needs for trophic material. The revealed changes obviously play a pathogenetic role in the formation and further development of PI.

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