Epican, a heparan sulfate proteoglycan form of CD44 on keratinocytes, is a cell-cell adhesion molecule

1993 ◽  
Vol 6 (1) ◽  
pp. 62 ◽  
Author(s):  
Leonard Milstone ◽  
Lisa Kugelman ◽  
John Haggerty
Keyword(s):  
Cell Adhesion ◽  
Heparan Sulfate ◽  
Adhesion Molecule ◽  
Cell Adhesion Molecule ◽  
Heparan Sulfate Proteoglycan ◽  
Sulfate Proteoglycan ◽  
A Cell ◽  
Cell Cell

Mutations of PVRL1, encoding a cell-cell adhesion molecule/herpesvirus receptor, in cleft lip/palate-ectodermal dysplasia

10.1038/78119 ◽  
2000 ◽  
Vol 25 (4) ◽  
pp. 427-430 ◽  
Author(s):  
Koji Suzuki ◽  
Diane Hu ◽  
Tania Bustos ◽  
Joel Zlotogora ◽  
Antonio Richieri-Costa ◽  
...  
Keyword(s):  
Cell Adhesion ◽  
Adhesion Molecule ◽  
Cell Adhesion Molecule ◽  
Cleft Lip ◽  
Ectodermal Dysplasia ◽  
Cleft Lip Palate ◽  
A Cell ◽  
Cell Cell

scholarly journals Isolation of a cell-surface receptor for chick neural retina adherons.

1985 ◽  
Vol 100 (1) ◽  
pp. 56-63 ◽  
Author(s):  
D Schubert ◽  
M LaCorbiere
Keyword(s):  
Cell Surface ◽  
Heparan Sulfate ◽  
Cell Aggregation ◽  
Neural Retina ◽  
Heparan Sulfate Proteoglycan ◽  
Cell Surface Receptor ◽  
Sulfate Proteoglycan ◽  
Surface Receptor ◽  
A Cell ◽  
Cell Cell

Embryonic chick neural retina cells release glycoprotein complexes, termed adherons, into their culture medium. When absorbed onto the surface of petri dishes, neural retina adherons increase the initial rate of neural retina cell adhesion. In solution they increase the rate of cell-cell aggregation. Cell-cell and adheron-cell adhesions of cultured retina cells are selectively inhibited by heparan-sulfate glycosaminoglycan, but not by chondroitin sulfate or hyaluronic acid, suggesting that a heparan-sulfate proteoglycan may be involved in the adhesion process. We isolated a heparan-sulfate proteoglycan from the growth-conditioned medium of neural retina cells, and prepared an antiserum against it. Monovalent Fab' fragments of these antibodies completely inhibited cell-adheron adhesion, and partially blocked spontaneous cell-cell aggregation. An antigenically and structurally similar heparan-sulfate proteoglycan was isolated from the cell surface. This proteoglycan bound directly to adherons, and when absorbed to plastic, stimulated cell-substratum adhesion. These data suggest that a heparan-sulfate proteoglycan on the surface of chick neural retina cells acted as a receptor for adhesion-mediating glycoprotein complexes (adherons).

767: N-Cadherinis Playing a Roleas a Cell-Cell Adhesion Molecule Under Impairedfunction of E-Cadherin and Cadherin-6 in Renal Cell Carcinoma

2004 ◽  
Vol 171 (4S) ◽  
pp. 203-204
Author(s):  
Toru Shimazui ◽  
Jack A. Schalken ◽  
Koji Kawai ◽  
Egbert Oosterwijk ◽  
Hideyuki Akaza
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Adhesion ◽  
Cell Carcinoma ◽  
Adhesion Molecule ◽  
Renal Cell ◽  
Cell Adhesion Molecule ◽  
A Cell ◽  
E Cadherin ◽  
Cell Cell
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