Composites based on bioderived polymers: potential role in tissue engineering: Vol VI: resorbable polymer fibers

Author(s):  
Monika Yadav ◽  
Kunwar Paritosh ◽  
Nidhi Pareek ◽  
Vivekanand Vivekanand
Nano LIFE ◽  
2012 ◽  
Vol 02 (04) ◽  
pp. 1230010 ◽  
Author(s):  
JEN-CHIEH WU ◽  
H. PETER LORENZ

Electrospinning is a process for generating micrometer or nanometer scale polymer fibers with large surface areas and high porosity. For tissue engineering research, the electrospinning technique provides a quick way to fabricate fibrous scaffolds with dimensions comparable to the extracellular matrix (ECM). A variety of materials can be used in the electrospinning process, including natural biomaterials as well as synthetic polymers. The natural biomaterials have advantages such as excellent biocompatibility and biodegradability, which can be more suitable for making biomimic scaffolds. In the last two decades, there have been growing numbers of studies of biomaterial fibrous scaffolds using the electrospinning process. In this review, we will discuss biomaterials in the electrospinning process and their applications in tissue engineering.


2013 ◽  
Vol 114 (12) ◽  
pp. 2729-2737 ◽  
Author(s):  
Xuefeng Hu ◽  
Ping Zhang ◽  
Zhenjie Xu ◽  
Hongdong Chen ◽  
Xin Xie

Author(s):  
Weiguo Qiu ◽  
Joseph Cappello ◽  
Xiaoyi Wu

Micro- and submicro-diameter protein fibers are fundamental building blocks of extra- and intra-cellular matrices, providing structural support, stability and protection to cells, tissues and organism [1]. Fabricating performance fibers of both naturally derived and genetically engineered proteins has been extensively pursued for a variety of biomedical applications, including tissue engineering and drug delivery [2]. Silk-elastin-like proteins (SELPs), consisting of tandemly repeated polypeptide sequences derived from silk and elastin, have been biosynthesized using recombinant DNA technique [3]. Their potential as a biomaterials in the form of hydrogels continues to be explored [4, 5]. This study will focus on the fabrication of robust, micro-diameter SELP fibers as biomaterials for tissue engineering applications.


2014 ◽  
Vol 11 (101) ◽  
pp. 20140459 ◽  
Author(s):  
Nelson Monteiro ◽  
Albino Martins ◽  
Rui L. Reis ◽  
Nuno M. Neves

Liposomes are vesicular structures made of lipids that are formed in aqueous solutions. Structurally, they resemble the lipid membrane of living cells. Therefore, they have been widely investigated, since the 1960s, as models to study the cell membrane, and as carriers for protection and/or delivery of bioactive agents. They have been used in different areas of research including vaccines, imaging, applications in cosmetics and tissue engineering. Tissue engineering is defined as a strategy for promoting the regeneration of tissues for the human body. This strategy may involve the coordinated application of defined cell types with structured biomaterial scaffolds to produce living structures. To create a new tissue, based on this strategy, a controlled stimulation of cultured cells is needed, through a systematic combination of bioactive agents and mechanical signals. In this review, we highlight the potential role of liposomes as a platform for the sustained and local delivery of bioactive agents for tissue engineering and regenerative medicine approaches.


2005 ◽  
Vol 74A (3) ◽  
pp. 338-346 ◽  
Author(s):  
Tadanao Funakoshi ◽  
Tokifumi Majima ◽  
Norimasa Iwasaki ◽  
Shintaro Yamane ◽  
Tatsuya Masuko ◽  
...  

2007 ◽  
Vol 7 (11) ◽  
pp. 3834-3840 ◽  
Author(s):  
Ho-Wang Tong ◽  
Min Wang

Fibrous membranes of aligned poly(hydroxybutyrate-co-hydroxyvalerate) (PHBV) fibers have been made through electrospinning. A high-speed rotating drum was used as the fiber collector while the electric field was manipulated by using five knife-edged auxiliary electrodes. It was found that a high drum rotating speed of 3000 rpm could lead to a nearly perfect alignment of PHBV fibers during electrospinning. Multilayered fibrous structures with each layer having a different direction of fiber alignment could also be constructed through electrospinning. The electrospun PHBV fibers were further modified by incorporating carbonated hydroxyapatite (HA) nanospheres (up to 20% of HA) in the fibers. The fibrous membranes made of aligned PHBV fibers and made of HA/PHBV composite fibers should be very useful for the tissue engineering of different human body tissues.


2016 ◽  
Vol 55 ◽  
pp. 70-78 ◽  
Author(s):  
Anja M. Boos ◽  
Annika Weigand ◽  
Rebekka Brodbeck ◽  
Justus P. Beier ◽  
Andreas Arkudas ◽  
...  

Author(s):  
Raymund E. Horch ◽  
Annika Weigand ◽  
Justus P. Beier ◽  
Andreas Arkudas ◽  
Anja M. Boos

Author(s):  
Natasha Maurmann ◽  
Juliana Girón ◽  
Bruna Borstmann Jardim Leal ◽  
Patricia Pranke

Electrospinning (ES) is an interesting and efficient technique for biomedical use. This is a method used for the fabrication of polymer fibers used in tissue engineering (TE). The electrospun nano- and microfibers biomaterial, called scaffolds, are also used for regenerative medicine. The aim of the present mini-review is to present methods used to fabricate 3D fibers by electrospinning and their applications in TE. Also, discussed here are issues regarding the electrospinning limitations and research challenges.


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