Electrospinning of Aligned Biodegradable Polymer Fibers and Composite Fibers for Tissue Engineering Applications

2007 ◽  
Vol 7 (11) ◽  
pp. 3834-3840 ◽  
Author(s):  
Ho-Wang Tong ◽  
Min Wang
Keyword(s):  
Tissue Engineering ◽  
Human Body ◽  
High Speed ◽  
Polymer Fibers ◽  
Rotating Drum ◽  
Composite Fibers ◽  
Fiber Alignment ◽  
Rotating Speed ◽  
Body Tissues ◽  
Fibrous Membranes

Fibrous membranes of aligned poly(hydroxybutyrate-co-hydroxyvalerate) (PHBV) fibers have been made through electrospinning. A high-speed rotating drum was used as the fiber collector while the electric field was manipulated by using five knife-edged auxiliary electrodes. It was found that a high drum rotating speed of 3000 rpm could lead to a nearly perfect alignment of PHBV fibers during electrospinning. Multilayered fibrous structures with each layer having a different direction of fiber alignment could also be constructed through electrospinning. The electrospun PHBV fibers were further modified by incorporating carbonated hydroxyapatite (HA) nanospheres (up to 20% of HA) in the fibers. The fibrous membranes made of aligned PHBV fibers and made of HA/PHBV composite fibers should be very useful for the tissue engineering of different human body tissues.

scholarly journals Influence of Nanofiber Orientation on Morphological and Mechanical Properties of Electrospun Chitosan Mats

2018 ◽  
Vol 2018 ◽  
pp. 1-12 ◽  
Author(s):  
Paola Nitti ◽  
Nunzia Gallo ◽  
Lara Natta ◽  
Francesca Scalera ◽  
Barbara Palazzo ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
High Speed ◽  
Soft Tissues ◽  
Electrospun Fiber ◽  
Rotating Disk ◽  
Rotating Drum ◽  
Fiber Morphology ◽  
Fiber Alignment ◽  
Poly Ethylene Oxide ◽  
Poly Ethylene

This work explored the use of chitosan (Cs) and poly(ethylene oxide) (PEO) blends for the fabrication of electrospun fiber-orientated meshes potentially suitable for engineering fiber-reinforced soft tissues such as tendons, ligaments, or meniscus. To mimic the fiber alignment present in native tissue, the CS/PEO blend solution was electrospun using a traditional static plate, a rotating drum collector, and a rotating disk collector to get, respectively, random, parallel, circumferential-oriented fibers. The effects of the different orientations (parallel or circumferential) and high-speed rotating collector influenced fiber morphology, leading to a reduction in nanofiber diameters and an improvement in mechanical properties.

scholarly journals Advanced mycelium materials as potential self-growing biomedical scaffolds

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Maria Elena Antinori ◽  
Marco Contardi ◽  
Giulia Suarato ◽  
Andrea Armirotti ◽  
Rosalia Bertorelli ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Low Cost ◽  
Direct Interaction ◽  
Dermal Fibroblasts ◽  
Engineering Systems ◽  
Edible Fungi ◽  
Avant Garde ◽  
Fibrous Network ◽  
Body Tissues ◽  
Wide Range

AbstractMycelia, the vegetative part of fungi, are emerging as the avant-garde generation of natural, sustainable, and biodegradable materials for a wide range of applications. They are constituted of a self-growing and interconnected fibrous network of elongated cells, and their chemical and physical properties can be adjusted depending on the conditions of growth and the substrate they are fed upon. So far, only extracts and derivatives from mycelia have been evaluated and tested for biomedical applications. In this study, the entire fibrous structures of mycelia of the edible fungi Pleurotus ostreatus and Ganoderma lucidum are presented as self-growing bio-composites that mimic the extracellular matrix of human body tissues, ideal as tissue engineering bio-scaffolds. To this purpose, the two mycelial strains are inactivated by autoclaving after growth, and their morphology, cell wall chemical composition, and hydrodynamical and mechanical features are studied. Finally, their biocompatibility and direct interaction with primary human dermal fibroblasts are investigated. The findings demonstrate the potentiality of mycelia as all-natural and low-cost bio-scaffolds, alternative to the tissue engineering systems currently in place.

ELECTROSPINNING OF BIOMATERIALS AND THEIR APPLICATIONS IN TISSUE ENGINEERING

Nano LIFE ◽  
2012 ◽  
Vol 02 (04) ◽  
pp. 1230010 ◽  
Author(s):  
JEN-CHIEH WU ◽  
H. PETER LORENZ
Keyword(s):  
Tissue Engineering ◽  
Electrospinning Process ◽  
Polymer Fibers ◽  
Nanometer Scale ◽  
High Porosity ◽  
Electrospinning Technique ◽  
Engineering Research ◽  
Fibrous Scaffolds ◽  
Surface Areas ◽  
Tissue Engineering Research

Electrospinning is a process for generating micrometer or nanometer scale polymer fibers with large surface areas and high porosity. For tissue engineering research, the electrospinning technique provides a quick way to fabricate fibrous scaffolds with dimensions comparable to the extracellular matrix (ECM). A variety of materials can be used in the electrospinning process, including natural biomaterials as well as synthetic polymers. The natural biomaterials have advantages such as excellent biocompatibility and biodegradability, which can be more suitable for making biomimic scaffolds. In the last two decades, there have been growing numbers of studies of biomaterial fibrous scaffolds using the electrospinning process. In this review, we will discuss biomaterials in the electrospinning process and their applications in tissue engineering.

Experimental Investigation on Cavitation Characteristics of a Three-Groove Journal Bearing

2013 ◽  
Vol 420 ◽  
pp. 47-50
Author(s):  
Ying Yang ◽  
Jing Hua Dai
Keyword(s):  
Experimental Investigation ◽  
High Speed ◽  
Journal Bearing ◽  
Rupture Zone ◽  
Work Characteristics ◽  
Oil Film ◽  
Rotating Speed ◽  
Clear Effect ◽  
Supply Pressure

Under high and super-high speed, oil film of the journal bearing is easy to crack and then becomes cavitation. The existence of cavitation has an important effect on the work characteristics of the shaft. On the journal bearing experiment rig the cavitation characteristics of the three-groove journal beaing were studied. The influences of the shaft rotating speed and supply pressure on cavitation shape were investigated. The results show that rotating speed and supply pressure have a clear effect on the cavitation shape, and the number of cavitation strip in the rupture zone decreases when the supply pressure increases.

Ultrasonic intra-body communication using semi-guided waves through human body tissues

2021 ◽  
Vol 150 (4) ◽  
pp. A31-A31
Author(s):  
John O. Gerguis ◽  
Mayukh Nath ◽  
Shreyas Sen
Keyword(s):  
Human Body ◽  
Guided Waves ◽  
Body Tissues

Experimental Research on Cavitation Characteristics of a Novel Hybrid Journal Bearing

2013 ◽  
Vol 420 ◽  
pp. 74-77
Author(s):  
Ying Yang ◽  
Jing Hua Dai ◽  
Xu Li
Keyword(s):  
Experimental Research ◽  
High Speed ◽  
Work Performance ◽  
Journal Bearing ◽  
Rupture Zone ◽  
Oil Film ◽  
Rotating Speed ◽  
Supply Pressure ◽  
Experimental Rig

Under high and super high speed, the oil film of a journal bearing is easy to crack and then becomes cavitation. The existence of cavitation has a great effect on the work performance of the bearing. The cavitation mechanism of a spiral oil wedge journal bearing was investigated on the experimental rig. The effects of rotating speed and supply pressure on the cavitation shape of oil film and the number of cavitation strip in the rupture zone were analyzed. The results show that the cavitation shape of oil film is a long strip. The number of cavitation strip increases when supply pressure has been improved, and the location of oil outlet must be designed optimally.

A New Dual-Channel Analyzer for Vibration of Rotary Machine

2008 ◽  
Author(s):  
Qing He ◽  
Dongmei Du
Keyword(s):  
Vibration Analysis ◽  
High Speed ◽  
Integral Transform ◽  
Vibration Measurement ◽  
Waveform Analysis ◽  
Rotating Speed ◽  
Rotary Machine ◽  
Vibration Sensors ◽  
Dual Channel ◽  
Channel Analyzer

A new simultaneous sampling and analyzer for dual-channel signal of vibration for rotating machine is developed based on the C8051F060, which is a high-speed SoC system and has two ADCs embedded with high sampling frequency. The signal condition circuits for various vibration sensors are designed, such as charge amplifier, integral transform and rotating speed detector. A colorful TFT LCD used can display all kinds of vibration analysis plots that are friendly in human-machine interface. The large capability non-volatile memory is used to restore up to one hundred of group of vibration waves. With many typical functions of vibration analysis, including waveform analysis, spectrum, orbit and balancing, this instrument is widely applied to vibration measurement and fault diagnosis of machine and equipment, especially for field balancing of rotary machine.

Experimental Study on Cavitation Boundary of Journal Bearing

2013 ◽  
Vol 378 ◽  
pp. 362-366
Author(s):  
Ying Yang ◽  
Li Xu ◽  
Wen Qing Liu
Keyword(s):  
Experimental Study ◽  
High Speed ◽  
Journal Bearing ◽  
Theory Model ◽  
Work Characteristics ◽  
Oil Film ◽  
Rotating Speed ◽  
Supply Pressure ◽  
Rupture Area ◽  
Experimental Rig

Under high and super-high speed conditions, oil film of the journal bearing is easy to crack and then becomes cavitation. The existence of cavitation has a great effect on the work characteristics of the bearing. Cavitation boundary of a three-groove journal beaing was investigated on the journal bearing experimental rig. The influences of rotating speed and supply pressure on cavitation boundary were studied. And experimental equations of reformation location and the percent of rupture area are established. The results show that rupture location of oil film is not related with rotating speed and supply pressure, otherwise reformation location of oil film is effected greatly by them. The experimental equations lay foundations for next research on cavitation theory model and stability.

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