Immunolocalization of NaV1.2 channel subtypes in rat and cat brain and spinal cord with high affinity antibodies

Caprine β-mannosidosis, an autosomal recessive defect of glycoprotein catabolism, is associated with a deficiency of tissue and plasma -mannosidase and with tissue accumulation and urinary excretion of oligosaccharides, including the trisaccharide Man(β1-4)GlcNAc(βl-4)GlcNAc and the disaccharide Man(β1-4)GlcNAc. This genetic disorder is evident at birth, with severe neurological deficits including a marked intention tremor, pendular nystagmus, ataxia and inability to stand. Major pathological characteristics described in Nubian goats in Michigan and in Anglo-Nubian goats in New South Wales include widespread cytoplasmic vacuolation in the nervous system and viscera, axonal spheroids, and severe myelin paucity in the brain but not spinal cord or peripheral nerves. Light microscopic examination revealed marked regional variation in the severity of central nervous system myelin deficits, with some brain areas showing nearly complete absence of myelin and other regions characterized by the presence of 25-50% of the control number of myelin sheaths.

Download Full-text

Electrical Relations of the Brain and Spinal Cord

Scientific American ◽

10.1038/scientificamerican07121890-12114asupp ◽

1890 ◽

Vol 30 (758supp) ◽

pp. 12114-12114

Keyword(s):

Spinal Cord ◽

Brain And Spinal Cord ◽

The Brain

Download Full-text

UPAYA PENINGKATAN KEMAMPUAN MOTORIK KASAR ANAK DOWN SYNDROME DENGAN OLAHRAGA BOLA KAKI DI GOLDEN KIDS

Jurnal Selaras : Kajian Bimbingan dan Konseling serta Psikologi Pendidikan ◽

10.33541/sel.v1i2.928 ◽

2019 ◽

Vol 1 (2) ◽

pp. 139-151

Author(s):

Sinto Robindo ◽

Melda Rumia Rosmeri Simorangkir

Keyword(s):

Spinal Cord ◽

Down Syndrome ◽

Cognitive Abilities ◽

Body Movement ◽

Movement Control ◽

Fine Motor ◽

Educational Goals ◽

Motor Movement ◽

Brain And Spinal Cord ◽

Syndrome Child

ABSTRACT All aspects of development are very important in a person's life where the development of cognition, affection and psychomotor is well developed in accordance with its development, these three aspects can be said to be good and successful if the three aspects develop well. Like wise with the psychomotor aspect where between gross motor and fine motor are also balanced. Motoric is the development of coordinated body movement control between nerves, brain, and spinal cord (spinal cord or spinal cord). Child's gross motorization can be optimized by improving his motor movement coordination skills through physical activity in the form of coordination of body movements. Like throwing, catching, kicking, running, melopat, and maintaining balance. The condition of a Down Syndrome child who experiences weakness in the ability to think will affect in all aspects of his life. Down syndrome children have problems in cognitive abilities, effective and self-care abilities. This results in them needing special education. Basically, the educational goals that children with Down Syndrome want to achieve are not different from those of education in general. Because Down Syndrome children themselves are born in the midst of society. Keywords: football sports, gross motoric, down syndrome

Download Full-text