scholarly journals Naturally acquired human infections with the simian malaria parasite, Plasmodium cynomolgi, in Sarawak, Malaysian Borneo

2018 ◽  
Vol 73 ◽  
pp. 68 ◽  
Author(s):  
B. Singh ◽  
K.A. Kadir ◽  
T.H. Hu ◽  
T.N. Raja ◽  
D.S. Mohamad ◽  
...  
Keyword(s):  
Malaria Parasite ◽  
Simian Malaria ◽  
Plasmodium Cynomolgi ◽  
Parasite Plasmodium ◽  
Human Infections ◽  
Malaysian Borneo

scholarly journals Cytokines kill malaria parasites during infection crisis: extracellular complementary factors are essential.

1991 ◽  
Vol 173 (3) ◽  
pp. 523-529 ◽  
Author(s):  
T S Naotunne ◽  
N D Karunaweera ◽  
G Del Giudice ◽  
M U Kularatne ◽  
G E Grau ◽  
...  
Keyword(s):  
Tumor Necrosis Factor ◽  
Malaria Infection ◽  
Malaria Parasite ◽  
Tumor Necrosis ◽  
Mosquito Vector ◽  
Killing Activity ◽  
Simian Malaria ◽  
Plasmodium Cynomolgi ◽  
Parasite Plasmodium ◽  
Necrosis Factor

Malaria infection crisis, at which the parasitemia drops precipitously and the parasite loses infectivity to the mosquito vector, occurs in many natural malaria systems, and has not been explained. We demonstrate that in a simian malaria parasite (Plasmodium cynomolgi in its natural host, the toque monkey), the loss of infectivity during crisis is due to the death of circulating intraerythrocytic gametocytes mediated by crisis serum. These parasite-killing effects in crisis serum are due to the presence in the serum of cytokines tumor necrosis factor and interferon gamma, which are produced by the host as a result of the malaria infection. The killing activity of each cytokine is absolutely dependent upon the presence of additional, as yet unidentified factor(s) in the crisis serum.

scholarly journals Novel vectors of the zoonotic malaria parasite, Plasmodium knowlesi, in two districts of Sarawak, Malaysian Borneo

2018 ◽  
Vol 73 ◽  
pp. 75
Author(s):  
J. Ang Xin De ◽  
K. Abdul Kadir ◽  
D.S. Awang Mohamad ◽  
A. Matusop ◽  
K. Yaman ◽  
...  
Keyword(s):  
Malaria Parasite ◽  
Plasmodium Knowlesi ◽  
Zoonotic Malaria ◽  
Parasite Plasmodium ◽  
Malaysian Borneo

scholarly journals Asymptomatic Natural Human Infections With the Simian Malaria Parasites Plasmodium cynomolgi and Plasmodium knowlesi

2018 ◽  
Vol 219 (5) ◽  
pp. 695-702 ◽  
Author(s):  
Mallika Imwong ◽  
Wanassanan Madmanee ◽  
Kanokon Suwannasin ◽  
Chanon Kunasol ◽  
Thomas J Peto ◽  
...  
Keyword(s):  
Plasmodium Knowlesi ◽  
Malaria Parasites ◽  
Simian Malaria ◽  
Plasmodium Cynomolgi ◽  
Human Infections
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