An exploratory screening study for type 2 diabetes in hospitalized, adult medicine patients

Author(s):  
Laila Rkieh ◽  
Anjana Sengar ◽  
Amish Parikh ◽  
Allan Mills
2005 ◽  
Vol 14 (6) ◽  
pp. 1501-1509 ◽  
Author(s):  
Marcel C. Adriaanse ◽  
Jacqueline M. Dekker ◽  
Annemieke M. W. Spijkerman ◽  
Jos W. R. Twisk ◽  
Giel Nijpels ◽  
...  

2019 ◽  
Vol 22 (2) ◽  
pp. 127-130
Author(s):  
Galina A. Melnichenko ◽  
Marina V. Shestakova ◽  
Roman V. Rozhivanov

BACKGROUND: Hypogonadism is a common complication in men with type 2 diabetes mellitus (DM), but its prevalence remains unknown. AIMS: To estimate the prevalence of hypogonadism in men with type 2 DM. MATERIALS AND METHODS: Male patients with type 2 DM were enrolled into a single-cohort contemporaneous multicenter non-interventional screening study. The study period was from November 2017 through August 2018. Assessments included total testosterone, luteinizing hormone (LH), sex hormone-binding globulin, HbA1c levels. Levels of free testosterone were calculated by Vermeullen method. RESULTS: TheThe median of age of 400 included men was 56 years [51; 58], total testosterone was 12.3 [9.2; 16.5] nmol/l, free testosterone 270 [217; 334] pmol/l, HbA1c 7,1% [6.1; 8.6]. Hypogonadism was found in 135 men (33.7%). The total testosterone level in that group was 7.9 [6.8; 9.8] nmol/l, and free testosterone 192 [164; 227] pmol/l. In hypogonadism-free men their levels were 15,1 [12,4; 18,6] nmol/l and 311 [270; 364] pmol/l, respectively. In most patients with hypogonadism LH level was low, but within normal ranges, and significantly lower than in men without hypogonadism 3.2 [2.1; 4.7] IU/L vs 3.8 [2.7; 4.9] IU/L, respectively (p=0.007). Most commonly hypogonadism was with normal LH levels (92,6%, median LH level 3.2 [2.2; 4.3] IU/L, p0,001). The frequency of hypogonadism with high LH level (10.2 [9.2; 14.7] IU/L) and low LH level (1.0 [0.6; 1.1] IU/L) was 4.4% and 3.0%, respectively. CONCLUSIONS: The prevalence of hypogonadism in men with type 2 DM was found to be 33.7%. Normal levels of LH are typical for this type of patients with hypogonadism.


2004 ◽  
Vol 21 (9) ◽  
pp. 992-998 ◽  
Author(s):  
M. C. Adriaanse ◽  
F. J. Snoek ◽  
J. M. Dekker ◽  
A. M. W. Spijkerman ◽  
G. Nijpels ◽  
...  

2016 ◽  
Vol 62 (2) ◽  
pp. 209-216 ◽  
Author(s):  
Simona Cernea ◽  
Cristian Zoltai ◽  
Daniela Berbecilă ◽  
Floredana-Laura Şular

AbstractObjective: The aim of this study was to assess the prevalence of depression, anxiety and cognitive impairment in patients with type 2 diabetes (T2D).Material and methods: We conducted a cross-sectional study in patients with T2D. Depression and anxiety were assessed by questionnaires (PHQ-9, CES-D and GAD-7 respectively), cognitive function by the MoCA test. Additionally, 503 patients’ clinic charts were separately analyzed in order to compare the data recorded in the charts with that resulted from the active assessment.Results: In the screening study 216 subjects with T2D were included (62.2 ± 7.8 years old). 34.3% of them had depression and 7.4% presented major depression. 44.9% of patients with T2D had anxiety (9.2% major anxiety) and this was highly correlated with depression (OR: 21.139, 95%CI: 9.767-45.751; p<0.0001). Women had significantly higher prevalence of depression and anxiety compared to men (42.1% vs. 21.7%; p: 0.0021 and 51.1% vs. 34.9%; p: 0.02), but severe depression was similar between genders (9.0% vs. 4.8%; p: 0.29). Significantly more patients had depression and anxiety than recorded in their charts (34.3% vs. 13.9% and 44.9% vs. 9.3%, respectively; p<0.0001 for both). 69.0% of T2D patients had mild, 6.0% had moderate and none had severe cognitive dysfunction, respectively. Significantly more patients with depression and anxiety had mild and moderate cognitive impairment (p: 0.03 and p: 0.04, respectively).Conclusions: Patients with T2D had a high prevalence of comorbid depression, anxiety and cognitive impairment. Depression and anxiety were significantly more frequent in women. These conditions were under-evaluated and/or under-reported.


2016 ◽  
Vol 37 (1) ◽  
pp. 63-68
Author(s):  
Ozcan Karaman ◽  
Sayid Shafi Zuhur ◽  
Esra Cil ◽  
Aysenur Ozderya ◽  
Feyza Yener Ozturk ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document