The emotional burden of chronic skin disease dominates physical factors among women, adversely affecting quality of life and sexual function

Background/Aim: Hidradenitis suppurativa (HS) is a chronic skin disease with a heavy impact on patients’ quality of life (QoL). The aim of this study was to evaluate in detail the QoL impact of HS comparing it with other skin conditions, and in particular with psoriasis. Methods: Patients with a diagnosis of HS were recruited. QoL was measured using the Skindex-17 questionnaire. Results: Data were available for 69 HS patients. HS had the worst QoL among several skin conditions. Compared to psoriasis the mean symptom score was 69.4 versus 53.7, and the mean psychosocial score was 56.1 versus 32.7. Overall, the scores of patients with HS were higher than those of psoriasis patients on 16 of the 17 items of the Skindex-17. Conclusions: When compared to many different skin conditions, and in particular to psoriasis, HS was the most impairing condition, even at low levels of clinical severity.

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Consumer Quality Index Chronic Skin Disease (CQI-CSD): a new instrument to measure quality of care from the patient's perspective

British Journal of Dermatology ◽

10.1111/bjd.13957 ◽

2015 ◽

Vol 173 (4) ◽

pp. 1032-1040 ◽

Cited By ~ 2

Author(s):

O.D. van Cranenburgh ◽

M.W. Krol ◽

M.C.P. Hendriks ◽

M.A. de Rie ◽

E.M.A. Smets ◽

...

Keyword(s):

Quality Of Care ◽

Skin Disease ◽

Quality Index ◽

Patient’S Perspective ◽

New Instrument ◽

Consumer Quality Index ◽

Chronic Skin ◽

Chronic Skin Disease

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Rosacea: an update on therapeutic options

International Journal of Research in Dermatology ◽

10.18203/issn.2455-4529.intjresdermatol20183153 ◽

2018 ◽

Vol 4 (3) ◽

pp. 272

Author(s):

Imran Majid ◽

Shabir Ahmad Bhat

Keyword(s):

Skin Disease ◽

Treatment Options ◽

Psychological Impact ◽

Patient Treatment ◽

Inflammatory Skin Disease ◽

The Face ◽

Chronic Skin ◽

Systemic Agents ◽

Chronic Skin Disease

Rosacea is a common inflammatory skin disease affecting the face usually in middle-aged individuals. The disorder is associated with a lot of psychological impact on the quality of life of the affected patient. Treatment options for this skin disease range from topical treatment options to systemic agents and even lasers. This paper will review the current and some of the upcoming treatment options for this chronic skin disease.

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Dermatitis Atópica en Adultos

Revista Ciencia y Salud: Integrando conocimientos ◽

10.34192/cienciaysalud.v4i5.200 ◽

2020 ◽

Vol 4 (5) ◽

Author(s):

Luis Seas Garita ◽

Maria Fernanda Ochoa Perez ◽

Alison Villachica Madriz

Keyword(s):

Quality Of Life ◽

Atopic Dermatitis ◽

Multifactorial Disease ◽

Atopic Diseases ◽

Negative Effects ◽

Calidad De Vida ◽

Immunological Factors ◽

Chronic Skin ◽

Chronic Skin Disease

Resumen La dermatitis atópica o eczema, es la enfermedad cutánea crónica en recaídas más común, que afecta tanto a niños como adultos en todo el mundo y que aparece con frecuencia en familias con otras enfermedades atópicas como el asma, la rinitis alérgica y la alergia alimentaria. Se trata de una enfermedad multifactorial que resultante de la interacción de factores ambientales, defectos en la función barrera y una serie de factores inmunológicos. Este artículo ofrece una visión actualizada de la epidemiología, diagnóstico, tratamiento, prevención y factores que ayudan a disminuir los efectos negativos de la dermatitis atópica en la calidad de vida de los pacientes. Abstract Atopic dermatitis, or eczema, is the most common chronic skin disease in relapses, affecting both children and adults worldwide and appearing frequently in families with other atopic diseases such as asthma, allergic rhinitis, and food allergy. It is a multifactorial disease that results from the interaction of environmental factors, defects in barrier function and a series of immunological factors. This article offers an updated view of the epidemiology, diagnosis, treatment, prevention and factors that help decrease the negative effects of atopic dermatitis on the quality of life of patients.

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Paracrystalline Aggregates of Psoriatic Keratin and Their Relation to Normal Keratin Structure

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100120096 ◽

1985 ◽

Vol 43 ◽

pp. 680-681

Author(s):

S. Trachtenberg ◽

P.M. Steinert ◽

B.L. Trus ◽

A.C. Steven

Keyword(s):

Cell Death ◽

Stratum Corneum ◽

Intermediate Filament ◽

Skin Disease ◽

Amorphous Matrix ◽

Terminal Differentiation ◽

Proteolytic Degradation ◽

Horny Layer ◽

Chronic Skin ◽

Chronic Skin Disease

During terminal differentiation of vertebrate epidermis, certain specific keratin intermediate filament (KIF) proteins are produced. Keratinization of the epidermis involves cell death and disruption of the cytoplasm, leaving a network of KIF embedded in an amorphous matrix which forms the outer horny layer known as the stratum corneum. Eventually these cells are shed (desquamation). Normally, the processes of differentiation, keratinization, and desquamation are regulated in an orderly manner. In psoriasis, a chronic skin disease, a hyperkeratotic stratum corneum is produced, resulting in abnormal desquamation of unusually large scales. In this disease, the normal KIF proteins are diminished in amount or absent, and other proteins more typical of proliferative epidermal cells are present. There is also evidence of proteolytic degradation of the KIF.

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