The subcellular localization of OTX2 is cell-type specific and developmentally regulated in the mouse retina

2000 ◽  
Vol 78 (1-2) ◽  
pp. 26-37 ◽  
Author(s):  
D Baas ◽  
K.M Bumsted ◽  
J.A Martinez ◽  
F.M Vaccarino ◽  
K.C Wikler ◽  
...  
Keyword(s):  
Subcellular Localization ◽  
Mouse Retina ◽  
Cell Type ◽  
Developmentally Regulated ◽  
Cell Type Specific

Expression of the Ly-6 family proteins Lynx1 and Ly6H in the rat brain is compartmentalized, cell-type specific, and developmentally regulated

2013 ◽  
Vol 219 (6) ◽  
pp. 1923-1934 ◽  
Author(s):  
Morten Skøtt Thomsen ◽  
Betül Cinar ◽  
Majbrit Myrup Jensen ◽  
Ekaterina N. Lyukmanova ◽  
Mikhail A. Shulepko ◽  
...  
Keyword(s):  
Rat Brain ◽  
Cell Type ◽  
Developmentally Regulated ◽  
Cell Type Specific

scholarly journals Cell Type-Specific Subcellular Localization of Phospho-TBK1 in Response to Cytoplasmic Viral DNA

PLoS ONE ◽  
2013 ◽  
Vol 8 (12) ◽  
pp. e83639 ◽  
Author(s):  
Takayuki Suzuki ◽  
Hiroyuki Oshiumi ◽  
Moeko Miyashita ◽  
Hussein Hassan Aly ◽  
Misako Matsumoto ◽  
...  
Keyword(s):  
Subcellular Localization ◽  
Cell Type ◽  
Viral Dna ◽  
Cell Type Specific

scholarly journals Dopamine D1 receptor expression is bipolar cell type-specific in the mouse retina

2015 ◽  
Vol 524 (10) ◽  
pp. 2059-2079 ◽  
Author(s):  
Pershang Farshi ◽  
Bozena Fyk-Kolodziej ◽  
David M. Krolewski ◽  
Paul D. Walker ◽  
Tomomi Ichinose
Keyword(s):  
Bipolar Cell ◽  
Dopamine D1 Receptor ◽  
D1 Receptor ◽  
Receptor Expression ◽  
Mouse Retina ◽  
Cell Type ◽  
Cell Type Specific

scholarly journals Phosphatidylinositol 3,5-bisphosphate plays a role in the activation and subcellular localization of mechanistic target of rapamycin 1

2012 ◽  
Vol 23 (15) ◽  
pp. 2955-2962 ◽  
Author(s):  
Dave Bridges ◽  
Jing-Tyan Ma ◽  
Sujin Park ◽  
Ken Inoki ◽  
Lois S. Weisman ◽  
...  
Keyword(s):  
Plasma Membrane ◽  
Subcellular Localization ◽  
Target Of Rapamycin ◽  
Class Iii ◽  
Cell Type ◽  
Phosphatidylinositol 3 Kinase ◽  
Mechanistic Target Of Rapamycin ◽  
Cell Type Specific ◽  
Stepwise Formation ◽  
Phosphatidylinositol 3

The kinase complex mechanistic target of rapamycin 1 (mTORC1) plays an important role in controlling growth and metabolism. We report here that the stepwise formation of phosphatidylinositol 3-phosphate (PI(3)P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) regulates the cell type–specific activation and localization of mTORC1. PI(3)P formation depends on the class II phosphatidylinositol 3-kinase (PI3K) PI3K-C2α, as well as the class III PI3K Vps34, while PI(3,5)P2 requires the phosphatidylinositol-3-phosphate-5-kinase PIKFYVE. In this paper, we show that PIKFYVE and PI3K-C2α are necessary for activation of mTORC1 and its translocation to the plasma membrane in 3T3-L1 adipocytes. Furthermore, the mTORC1 component Raptor directly interacts with PI(3,5)P2. Together these results suggest that PI(3,5)P2 is an essential mTORC1 regulator that defines the localization of the complex.

scholarly journals Subcellular Localization of Axl1, the Cell Type-Specific Regulator of Polarity

2002 ◽  
Vol 12 (15) ◽  
pp. 1347-1352 ◽  
Author(s):  
Matthew Lord ◽  
Fumika Inose ◽  
Takatoshi Hiroko ◽  
Toshihiro Hata ◽  
Atsushi Fujita ◽  
...  
Keyword(s):  
Subcellular Localization ◽  
Cell Type ◽  
Cell Type Specific
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