Molecular Imaging Needs Lower Radiation Dose

2008 ◽  
Vol 41 (21) ◽  
pp. 26
Author(s):  
MITCHEL L. ZOLER
Diagnostics ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1209
Author(s):  
Gabriel Keller ◽  
Simon Götz ◽  
Mareen Sarah Kraus ◽  
Leonard Grünwald ◽  
Fabian Springer ◽  
...  

This study analyzed the radiation exposure of a new ultra-low dose (ULD) protocol compared to a high-quality (HQ) protocol for CT-torsion measurement of the lower limb. The analyzed patients (n = 60) were examined in the period March to October 2019. In total, 30 consecutive patients were examined with the HQ and 30 consecutive patients with the new ULD protocol comprising automatic tube voltage selection, automatic exposure control, and iterative image reconstruction algorithms. Radiation dose parameters as well as the contrast-to-noise ratio (CNR) and diagnostic confidence (DC; rated by two radiologists) were analyzed and potential predictor variables, such as body mass index and body volume, were assessed. The new ULD protocol resulted in significantly lower radiation dose parameters, with a reduction of the median total dose equivalent to 0.17 mSv in the ULD protocol compared to 4.37 mSv in the HQ protocol (p < 0.001). Both groups showed no significant differences in regard to other parameters (p = 0.344–0.923). CNR was 12.2% lower using the new ULD protocol (p = 0.033). DC was rated best by both readers in every HQ CT and in every ULD CT. The new ULD protocol for CT-torsion measurement of the lower limb resulted in a 96% decrease of radiation exposure down to the level of a single pelvic radiograph while maintaining good image quality.


1996 ◽  
Vol 69 (1) ◽  
pp. 120-129 ◽  
Author(s):  
Sujit K. Datta ◽  
Tapan K. Chaki ◽  
Anil K. Bhowmick

Abstract Electron beam irradiation of Ethylene vinyl acetate, EVA (VA content 12, 28 & 45%) copolymer was carried out in presence of trimethylolpropane trimethacrylate (TMPTMA) and triallyl cyanurate (TAC) and the structure of the modified copolymers was determined with the help of IR spectroscopy and gel content measurements. The IR absorbance peak at 1640 cm−1 disappears at lower radiation dose indicating that the grafting and crosslinking reactions take place through double bonds. Some carbonyl groups are formed during irradiation. The concentration of carbonyl group increases with the radiation dose and the level of multifunctional monomers. The grafting level of TAC onto EVA determined from IR absorbance peak at 1565 cmx−1 remains almost constant with the variation of radiation dose and increases with TAC level. The gel content increases with radiation dose, but changes marginally with TMPTMA and TAC levels. The percent gel content increases linearly with vinyl acetate content in EVA.


Author(s):  
Susan J. Copley ◽  
David M. Hansell

Radiographic findings should always be interpreted in conjunction with the clinical picture. Chest radiography—this remains the commonest technique in the investigation of suspected thoracic disease. Advantages are cost, availability, and a significantly lower radiation dose than CT, but even with optimal technique nearly one-third of the lungs are partially obscured by the overlying mediastinum, diaphragm, and ribs....


2013 ◽  
Vol 27 (1) ◽  
pp. 68-76 ◽  
Author(s):  
Helle Precht ◽  
Anders Tingberg ◽  
Dag Waaler ◽  
Claus Bjørn Outzen

Radiology ◽  
2008 ◽  
Vol 249 (2) ◽  
pp. 661-670 ◽  
Author(s):  
Monique Brink ◽  
Frank de Lange ◽  
Luuk J. Oostveen ◽  
Helena M. Dekker ◽  
Digna R. Kool ◽  
...  

2018 ◽  
Vol 59 (12) ◽  
pp. 1458-1465 ◽  
Author(s):  
Stefan Haneder ◽  
Florian Siedek ◽  
Jonas Doerner ◽  
Gregor Pahn ◽  
Nils Grosse Hokamp ◽  
...  

Background A novel, multi-energy, dual-layer spectral detector computed tomography (SDCT) is commercially available now with the vendor’s claim that it yields the same or better quality of polychromatic, conventional CT images like modern single-energy CT scanners without any radiation dose penalty. Purpose To intra-individually compare the quality of conventional polychromatic CT images acquired with a dual-layer spectral detector (SDCT) and the latest generation 128-row single-energy-detector (CT128) from the same manufacturer. Material and Methods Fifty patients underwent portal-venous phase, thoracic-abdominal CT scans with the SDCT and prior CT128 imaging. The SDCT scanning protocol was adapted to yield a similar estimated dose length product (DLP) as the CT128. Patient dose optimization by automatic tube current modulation and CT image reconstruction with a state-of-the-art iterative algorithm were identical on both scanners. CT image contrast-to-noise ratio (CNR) was compared between the SDCT and CT128 in different anatomic structures. Image quality and noise were assessed independently by two readers with 5-point-Likert-scales. Volume CT dose index (CTDIvol), and DLP were recorded and normalized to 68 cm acquisition length (DLP68). Results The SDCT yielded higher mean CNR values of 30.0% ± 2.0% (26.4–32.5%) in all anatomic structures ( P < 0.001) and excellent scores for qualitative parameters surpassing the CT128 (all P < 0.0001) with substantial inter-rater agreement (κ ≥ 0.801). Despite adapted scan protocols the SDCT yielded lower values for CTDIvol (–10.1 ± 12.8%), DLP (−13.1 ± 13.9%), and DLP68 (–15.3 ± 16.9%) than the CT128 (all P < 0.0001). Conclusion The SDCT scanner yielded better CT image quality compared to the CT128 and lower radiation dose parameters.


2010 ◽  
Vol 77 (4) ◽  
pp. 980-987 ◽  
Author(s):  
Sang-Hue Yen ◽  
Yi-Wei Chen ◽  
Pin-I Huang ◽  
Tai-Tong Wong ◽  
Donald Ming-Tak Ho ◽  
...  

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