scholarly journals In silicoexploration of the mechanisms that underlie parasite-induced anorexia in sheep

2011 ◽  
Vol 106 (7) ◽  
pp. 1023-1039 ◽  
Author(s):  
Yan C. S. M. Laurenson ◽  
Stephen C. Bishop ◽  
Ilias Kyriazakis
Keyword(s):  
Experimental Data ◽  
Food Intake ◽  
Protein Content ◽  
Energy Content ◽  
Direct Reduction ◽  
Food Composition ◽  
Low Energy ◽  
Published Data ◽  
Teladorsagia Circumcincta ◽  
Consequent Reduction

A model was used to investigate two mechanisms describing reductions in food intake (anorexia) observed during gastrointestinal parasitism in lambs, and to explore relationships between anorexia and food composition. The mechanisms were either a reduction in intrinsic growth rate, leading to a consequent reduction in food intake (mechanism 1; M1), or a direct reduction in food intake (mechanism 2; M2). For both mechanisms, lambs growing from 2 to 6 months of age were modelled, with one of three levels of trickle challenge withTeladorsagia circumcincta. Scenarios were simulated for feeds varying in either protein or energy content, or both. Major differences were found between the predictions resulting from M1 and M2 on low-energy foods that constrained the intake of uninfected lambs through bulk. With M1, food intake was governed by the first operating constraint, whereas with M2 an additivity of constraints was observed. On the other foods, the duration of anorexia increased with increasing energy content of feed for M1, whilst the duration of anorexia decreased with increasing protein content of feed for M2.For foods that did not have an impact upon lambs' gastrointestinal tract capacity, published data were consistent with predictions of M2. Due to an absence of experimental data, no conclusions could be drawn for relationships between anorexia and food composition in the presence of other limiting constraints, such as bulk for low-energy foods. In conclusion, available experimental data and model predictions were consistent with anorexia having an impact directly on food intake, and with impacts of anorexia increasing with decreasing protein content.

Pathogen-induced anorexia: a herbivore strategy or an unavoidable consequence of infection?

2014 ◽  
Vol 54 (9) ◽  
pp. 1190 ◽  
Author(s):  
Ilias Kyriazakis
Keyword(s):  
Immune Response ◽  
Food Intake ◽  
Feeding Behaviour ◽  
Infected Animal ◽  
Energy Content ◽  
Poor Quality ◽  
Low Energy ◽  
High Quality ◽  
Model Predictions ◽  
Voluntary Food Intake

A reduction in voluntary food intake is a common feature of infection with pathogens and is frequently referred to as pathogen-induced anorexia. Anorexia has been previously viewed either as an unavoidable consequence of infection or as an animal strategy that enables them to cope with the consequences of infection. Both approaches lead to certain expectations as far as the characteristics of anorexia are concerned. By linking anorexia to host immune response one should be able to make predictions about when and for how long anorexia would occur. By appreciating what an infected animal is trying to achieve through its feeding behaviour, one would be able to make predictions about the extent of anorexia on different quality foods. The thesis of the paper is that these approaches should no longer be viewed as mutually exclusive, but, by combining them, one should be able to make pathogen-induced anorexia more predictable. This is done in the development of a model that aims to predict the food intake of grazing sheep exposed to an abomasal parasite. The predictions of the model are consistent with the features and consequences of parasite-induced anorexia of sheep given access to moderate and high quality foods. However, there is a degree of uncertainty about the validity of predictions made by the model on anorexia seen on poor quality foods of low energy content. This is not a deficiency of the model developed but can be attributed to the lack of appropriate experiments against which model predictions can be tested.

scholarly journals Regulation of food intake during growth in fatty and lean female Zucker rats given diets of different protein content

1976 ◽  
Vol 36 (3) ◽  
pp. 457-469 ◽  
Author(s):  
J. D. Radcliffe ◽  
A. J. F. Webster
Keyword(s):  
Food Intake ◽  
Protein Content ◽  
Energy Deposition ◽  
Energy Content ◽  
Zucker Rats ◽  
Zucker Rat ◽  
Appetite Control ◽  
Protein Deposition ◽  
Obese Zucker Rat ◽  
Dietary Treatments

1. Food intake, and the rates of protein, lipid and energy deposition during growth were measured for lean and congenitally obese (fatty) female Zucker rats given diets of different protein content ad lib. Six semi-synthetic diets were used, which contained 40, 100, 150, 300, 500 and 700 g casein/kg (diets 40C, 100C, 150C, 300C, 500C and 700C).2. Dietary treatments began when the rats were 34 or 35 d old. Collections of urine and faeces were analysed for energy content. The total carcasses of all the rats were analysed individually for protein, lipid and energy.3. In the first experiment, twelve rats of each phenotype were given diets 150C or 300C. Four fatty and four lean rats were killed at 50, 66 and 98 d of age. In the second experiment groups of four fatty and four lean rats were given diets 40C, 100C, 500C and 700C ad lib. until they were killed at 66 d of age. Other groups of fatty rats were pair-fed from 35 to 67 d of age on diets 100C and 500C. Rats were also killed at 24 and 34 d of age to provide initial samples for the comparative slaughter procedure.4. When given food ad lib., fatty and lean rats had identical rates of protein deposition at all ages and for all diets, but lipid and energy deposition were always much greater in the fatty rats. Food intake was also much greater for the fatty rats (except on diet 40C). Differences in food intake and growth rate attributable to diet were most pronounced for the range of diets 40C-150C.5. Fatty rats pair-fed to lean rats deposited less protein but about twice as much energy and lipid as lean rats on the same diets.6. The results are discussed in relation to existing theories of appetite control. It appears that food intake is precisely regulated in the congenitally obese Zucker rat. This regulation is intimately linked with the impetus for protein deposition and the rates of retention of lipid and energy appear to be of no importance in relation to appetite control.

The effect of restricted access to food on the voluntary food intake of pigs

1978 ◽  
Vol 90 (1) ◽  
pp. 77-82
Author(s):  
D. Wyllie ◽  
J. B. Owen
Keyword(s):  
Food Intake ◽  
Food Access ◽  
Energy Content ◽  
Low Energy ◽  
Strong Reaction ◽  
Time Period ◽  
Obese Rats ◽  
Access To Food ◽  
Low Energy Diet ◽  
Voluntary Food Intake

SUMMARYTwo experiments were carried out to examine the effects of restricted food access on the voluntary food intake of pigs given diets of varying energy content or palatability. Where pigs were offered access to food for a restricted time period each day, the voluntary food intake was reduced in relation to the length of access allowed. Compensation was slow, particularly where a low-energy diet was fed. Younger pigs (35–45 kg) compensated faster than heavier pigs (100–110 kg). The responses of the heavier pigs appeared to be similar to those reported for genetically obese rats in their strong reaction to diets of different energy content or palatability.

scholarly journals Low-Energy Optical Conductivity of TaP: Comparison of Theory and Experiment

Crystals ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 567
Author(s):  
Alexander Yaresko ◽  
Artem V. Pronin
Keyword(s):  
Experimental Data ◽  
Optical Conductivity ◽  
Low Energy ◽  
Spin Orbit Coupling ◽  
Spin Orbit ◽  
Natural Explanation ◽  
Weyl Semimetal ◽  
Unintentional Doping ◽  
Mott Formula ◽  
Theory And Experiment

The ab-plane optical conductivity of the Weyl semimetal TaP is calculated from the band structure and compared to the experimental data. The overall agreement between theory and experiment is found to be best when the Fermi level is slightly (20 to 60 meV) shifted upwards in the calculations. This confirms a small unintentional doping of TaP, reported earlier, and allows a natural explanation of the strong low-energy (50 meV) peak seen in the experimental ab-plane optical conductivity: this peak originates from transitions between the almost parallel non-degenerate electronic bands split by spin-orbit coupling. The temperature evolution of the peak can be reasonably well reproduce by calculations using an analog of the Mott formula.

Global magnesium supply in the food chain

2015 ◽  
Vol 66 (12) ◽  
pp. 1278 ◽  
Author(s):  
Diriba B. Kumssa ◽  
Edward J. M. Joy ◽  
E. Louise Ander ◽  
Michael J. Watts ◽  
Scott D. Young ◽  
...  
Keyword(s):  
Food Composition ◽  
Published Data ◽  
Mg Deficiency ◽  
Individual Level ◽  
Household Food ◽  
Dietary Surveys ◽  
Food Composition Data ◽  
Per Capita ◽  
Potential Inhibitors ◽  
Dietary Deficiency

Magnesium (Mg) is an essential mineral micronutrient in humans. Risks of dietary Mg deficiency are affected by the quantity of Mg ingested and its bioavailability, which is influenced by the consumption of other nutrients and ‘anti-nutrients’. Here, we assess global dietary Mg supplies and risks of dietary deficiency, including the influence of other nutrients. Food supply and food composition data were used to derive the amount of Mg available per capita at national levels. Supplies of Mg were compared with estimated national per capita average requirement ‘cut points’. In 2011, global weighted mean Mg supply was 613 ± 69 mg person–1 day–1 compared with a weighted estimated average requirement for Mg of 173 mg person–1 day–1. This indicates a low risk of dietary Mg deficiency of 0.26% based on supply. This contrasts with published data from national individual-level dietary surveys, which indicate greater Mg deficiency risks. However, individuals in high-income countries are likely to under-report food consumption, which could lead to overestimation of deficiency risks. Furthermore, estimates of deficiency risk based on supply do not account for potential inhibitors of Mg absorption, including calcium, phytic acid and oxalate, and do not consider household food wastage.

Application of Polyhedral Mesh for Vortex Formation Study for Simple Single Pump Sump

CFD letters ◽  
2021 ◽  
Vol 13 (9) ◽  
pp. 13-27
Author(s):  
Mohamad Lutfi Samsudin ◽  
Hasril Hasini
Keyword(s):  
Experimental Data ◽  
Complex Geometry ◽  
Vortex Formation ◽  
Tetrahedral Mesh ◽  
Published Data ◽  
Hexahedral Mesh ◽  
The Past ◽  
Polyhedral Mesh ◽  
Pump Sump ◽  
Comparison Of The Results

Meshing of domain in CFD is an important step to ensure accuracy of the solution. In the past, hexahedral or tetrahedral mesh systems were commonly used, and both have their merits and demerits. For large and complex geometry, polyhedral is another option but its accuracy is claimed to be lacking. In this paper, the use of polyhedral mesh system by past researchers are reviewed. Evaluation on the application of polyhedral mesh system for the study of the vortex formation with a simple single pump sump model is made. Validation was made through the comparison of the results from hexahedral, tetrahedral and polyhedral mesh sizes and the experimental data from published data. The polyhedral mesh system was found to perform satisfactorily and was able to match the results from the hexahedral mesh system as well as the experimental data.

Net energy efficiencies of Holstein, Jersey and Holstein-Jersey F1-crosses

2001 ◽  
Vol 72 (2) ◽  
pp. 335-342 ◽  
Author(s):  
R. Schwager-Suter ◽  
C. Stricker ◽  
D. Erdin ◽  
N. Künzi
Keyword(s):  
Body Weight ◽  
Body Condition ◽  
Fixed Effects ◽  
Energy Content ◽  
High Energy ◽  
Repeated Measurements ◽  
Low Energy ◽  
Body Tissue ◽  
Net Energy ◽  
Tissue Change

Abstract Net energy efficiencies were calculated from data of an experimental herd with respect to type of cow, lactation number, stage of lactation and diet. The trial consisted of 71 Holstein-Friesians, 71 Jerseys and 71 Holstein-Jersey F1-crosses in 1st, 2nd and > 2nd lactation. Data were collected during 210 days of lactation, from calving to week 30 and included total dry matter intake, energy content of foods, milk yield, milk solids, body weight, body condition scores and several body measurements. The cows were divided into four feeding groups : high and low energy content of roughage as well as high and low proportion of concentrates. Net energy efficiency was calculated as the ratio of milk energy to total net energy intake after subtracting energy utilized for maintenance and body tissue change. Body tissue change was calculated either via body-weight changes or body condition-score changes. Due to the distribution of the efficiencies being skewed, efficiencies were transformed applying a Box-Cox transformation. Transformed net energy efficiencies were analysed using a repeated measurements design considering the sequential nature of the observations. Mixed models with a compound symmetry structure for the variance components were applied. Final models contained the fixed effects of type, lactation number, feeding group and the covariates week of lactation and its square. Holstein-Jersey crosses were more efficient than purebreds, second lactation cows were least efficient, cows given low energy roughage and a lower proportion of concentrates were more efficient than cows on the other diets. Least efficient were the cows belonging to the high energy roughage and higher proportion of concentrates group. The coefficients of determination of the final models were between 0·357 and 0·492.

CH4 Direct Reduction of In-Flight Fe3O4 Concentrate Particles

2018 ◽  
Vol 14 (1) ◽  
Author(s):  
Bahador Abolpour ◽  
M. Mehdi Afsahi ◽  
Ataallah Soltani Goharrizi
Keyword(s):  
Experimental Data ◽  
Mathematical Model ◽  
Fine Particles ◽  
Direct Reduction ◽  
Constant Heat Flux ◽  
Constant Heat ◽  
Dynamic Motion ◽  
Magnetite Ore ◽  
Model Predictions ◽  
Kinetics Of

Abstract In this study, reduction of in-flight fine particles of magnetite ore concentrate by methane at a constant heat flux has been investigated both experimentally and numerically. A 3D turbulent mathematical model was developed to simulate the dynamic motion of these particles in a methane content reactor and experiments were conducted to evaluate the model. The kinetics of the reaction were obtained using an optimizing method as: [-Ln(1-X)]1/2.91 = 1.02 × 10−2dP−2.07CCH40.16exp(−1.78 × 105/RT)t. The model predictions were compared with the experimental data and the data had an excellent agreement.

High-enthalpy, water-cooled and thin-walled ICP sources characterization and MHD optimization

2008 ◽  
Vol 74 (3) ◽  
pp. 391-429 ◽  
Author(s):  
G. HERDRICH ◽  
D. PETKOW
Keyword(s):  
Experimental Data ◽  
Magnetic Pressure ◽  
Maximum Pressure ◽  
Published Data ◽  
Space Vehicles ◽  
Maximum Plasma ◽  
Plasma Power ◽  
New Model ◽  
High Enthalpy ◽  
Lorentz Forces

AbstractThe development of the inductively driven plasma wind tunnel PWK3, which enables the electrodeless generation of high-enthalpy plasmas for the development of heat shield materials required for space vehicles performing entry manoeuvres in the atmospheres of Venus, Earth and Mars, is described. The facility with its modular inductive plasma generators allows operation with gases such as carbon dioxide, air, oxygen and nitrogen and was qualified for thermal plasma powers up to 60 kW. Previously developed models for determining plasma properties and plasma source related characteristics enable a maximum plasma power in combination with long operational periods using different operational gases and gas mixtures. This is achieved by an optimization using the optimum operational frequency, a minimization of field losses using very thin plasma tube wall thicknesses and the successful application of MHD effects. Based on the solved cylinder problem for ICPs, a one-dimensional model for radial Lorentz forces and magnetic pressure has been developed. Here, a synthesis of previously published data and works is made where the new algebraic model for the calculation of Lorentz forces and magnetic pressures in an ICP was used and applied to experimental data. In addition, results from the model using the experimental data are shown to be consistent and, in addition, a comparison with a simpler model based on the well-known exponential approach for ICPs showed that the simpler model is covered without fail by the new model. The new model also states that there is a maximum of the Lorentz forces over the damping parameter d/δ (plasma diameter divided by skin depth) which almost corresponds with the position of the maximum plasma power of the cylindric model for ICPs. For the magnetic pressure the position of the maximum pressure is identical to the value for d/δ for the maximum plasma power.

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