Synthesis of 6-substituted .beta.-carbolines that behave as benzodiazepine receptor antagonists or inverse agonists

Journal of Medicinal Chemistry ◽

10.1021/jm00387a033 ◽

1987 ◽

Vol 30 (4) ◽

pp. 750-753 ◽

Author(s):

Timothy J. Hagen ◽

Phil Skolnick ◽

James M. Cook

Keyword(s):

Benzodiazepine Receptor ◽

Receptor Antagonists ◽

Inverse Agonists

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ChemInform Abstract: Synthesis of 6-Substituted β-Carbolines that Behave as Benzodiazepine Receptor Antagonists or Inverse Agonists.

10.1002/chin.198737233 ◽

1987 ◽

Vol 18 (37) ◽

Author(s):

T. J. HAGEN ◽

P. SKOLNICK ◽

J. M. COOK

Keyword(s):

Benzodiazepine Receptor ◽

Receptor Antagonists ◽

Inverse Agonists

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The effects of benzodiazepine-receptor antagonists and partial inverse agonists on acute hepatic encephalopathy in the rat

Gastroenterology ◽

10.1016/0016-5085(91)90538-v ◽

1991 ◽

Vol 101 (3) ◽

pp. 772-781 ◽

Author(s):

Diederik K. Bosman ◽

Constantinus A.C.G. Van Den Buijs ◽

Jan G. De Haan ◽

Martinus A.W. Maas ◽

Robert A.F.M. Chamuleau

Keyword(s):

Hepatic Encephalopathy ◽

Benzodiazepine Receptor ◽

Receptor Antagonists ◽

Inverse Agonists ◽

Partial Inverse ◽

Acute Hepatic Encephalopathy

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Effects of the benzodiazepine inverse agonist RO19-4603 alone and in combination with the benzodiazepine receptor antagonists flumazenil, ZK 93426 and CGS 8216, on ethanol intake in alcohol-preferring (P) rats

Brain Research ◽

10.1016/0006-8993(96)00276-4 ◽

1996 ◽

Vol 734 (1-2) ◽

pp. 19-34 ◽

Author(s):

Harry L. June ◽

Terri L. Greene ◽

James M. Murphy ◽

Margaret L. Hite ◽

John A. Williams ◽

...

Keyword(s):

Benzodiazepine Receptor ◽

Inverse Agonist ◽

Ethanol Intake ◽

Receptor Antagonists ◽

Cgs 8216 ◽

Zk 93426 ◽

Benzodiazepine Inverse Agonist

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Dopamine receptor antagonists or inverse agonists as antipsychotics?

Biochemical Society Transactions ◽

10.1042/bst027a026c ◽

1999 ◽

Vol 27 (1) ◽

pp. A26-A26

Author(s):

Philip G. Strange

Keyword(s):

Dopamine Receptor ◽

Receptor Antagonists ◽

Inverse Agonists ◽

Dopamine Receptor Antagonists

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Effects of Benzodiazepine Receptor Inverse Agonists and Nicotine on Behavioral Vigilance in Senescent Rats

The Journals of Gerontology Series A ◽

10.1093/gerona/51a.3.b225 ◽

1996 ◽

Vol 51A (3) ◽

pp. B225-B231 ◽

Author(s):

J. Turchi ◽

L. A. Holley ◽

M. Sarter

Keyword(s):

Benzodiazepine Receptor ◽

Inverse Agonists

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Benzodiazepine-receptor antagonists and hepatic encephalopathy: Where do we stand?

Gastroenterology ◽

10.1016/0016-5085(93)90916-z ◽

1993 ◽

Vol 105 (3) ◽

pp. 937-940 ◽

Author(s):

Kevin D. Mullen ◽

Anthony S. Basile

Keyword(s):

Hepatic Encephalopathy ◽

Benzodiazepine Receptor ◽

Receptor Antagonists

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The effects of GABA and benzodiazepine receptor antagonists on the anti-conflict actions of diazepam or ethanol

Pharmacology Biochemistry and Behavior ◽

10.1016/s0091-3057(84)80033-7 ◽

1984 ◽

Vol 21 (4) ◽

pp. 521-525 ◽

Author(s):

Sture Liljequist ◽

Jorgen A. Engel

Keyword(s):

Benzodiazepine Receptor ◽

Receptor Antagonists

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Regiospecific Introduction of Halogens on the 2-Aminobiphenyl Subunit Leading to Highly Potent and Selective M3 Muscarinic Acetylcholine Receptor Antagonists and Weak Inverse Agonists

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.0c00297 ◽

2020 ◽

Vol 63 (8) ◽

pp. 4349-4369 ◽

Author(s):

Oliver Fischer ◽

Josefa Hofmann ◽

Hannelore Rampp ◽

Jonas Kaindl ◽

Gerald Pratsch ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Muscarinic Acetylcholine Receptor ◽

Receptor Antagonists ◽

Inverse Agonists ◽

Muscarinic Acetylcholine ◽

M3 Muscarinic Acetylcholine Receptor

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Cannabinoid Cb1 Receptor Antagonists/Inverse Agonists and Food-Seeking Behavior

Handbook of Behavior, Food and Nutrition ◽

10.1007/978-0-387-92271-3_29 ◽

2011 ◽

pp. 441-456

Author(s):

John D. Salamone ◽

Kelly Sink ◽

Kristen N. Segovia ◽

Patrick A. Randall ◽

Peter J. McLaughlin ◽

...

Keyword(s):

Cb1 Receptor ◽

Cannabinoid Cb1 Receptor ◽

Receptor Antagonists ◽

Inverse Agonists ◽

Seeking Behavior ◽

Food Seeking ◽

Cb1 Receptor Antagonists

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”Audiogenic seizures in DBA/2 mice discriminate sensitivity between low efficacy benzodiazepine receptor agonists and inverse agonists,”

Life Sciences ◽

10.1016/0024-3205(83)90731-2 ◽

1983 ◽

Vol 33 (17) ◽

pp. 1731

Keyword(s):

Benzodiazepine Receptor ◽

Audiogenic Seizures ◽

Inverse Agonists ◽

Receptor Agonists

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