The Influence of Hypertension on Microvascular Blood Flow and Resistance to Flow in the Skin of Type 2 Diabetic Patients

1994 ◽  
Vol 86 (s30) ◽  
pp. 42P-43P
Author(s):  
AJ Jaap ◽  
AC Shore ◽  
JE Tooke
PLoS ONE ◽  
2021 ◽  
Vol 16 (7) ◽  
pp. e0254980
Author(s):  
Tsuneaki Omae ◽  
Youngseok Song ◽  
Takafumi Yoshioka ◽  
Tomofumi Tani ◽  
Akitoshi Yoshida

This study aimed to evaluate whether long-term insulin treatment is associated with abnormalities in retinal circulation in type 2 diabetic patients. We evaluated 19 eyes of nondiabetic individuals and 68 eyes of type 2 diabetic patients. The eyes of diabetic patients were classified into two groups according to the presence or absence of long-term insulin therapy. We used a Doppler optical coherence tomography flowmeter to measure diameter, velocity, and blood flow in the major temporal retinal artery. The pulsatility ratio (PR) and resistance index (RI), indices of vascular rigidity, were calculated from the blood velocity profile. PR and RI were significantly elevated in type 2 diabetic patients compared with nondiabetic subjects (P < 0.05). In type 2 diabetes patients, PR and RI were significantly higher in patients receiving long-term insulin treatment than in those without (P < 0.01). There was a significant difference in velocity (P < 0.05), but not diameter and blood flow, between nondiabetic subjects and type 2 diabetes patients. No significant difference in diameter, velocity, or blood flow was observed between the groups with and without long-term insulin treatment. Long-term insulin treatment can affect PR and RI, which might be associated with vascular rigidity of the retinal artery in patients with type 2 diabetes.


2009 ◽  
Vol 50 (12) ◽  
pp. 1993-1998 ◽  
Author(s):  
M. Kaplar ◽  
G. Paragh ◽  
A. Erdei ◽  
E. Csongradi ◽  
E. Varga ◽  
...  

2006 ◽  
Vol 43 (4) ◽  
pp. 760-770 ◽  
Author(s):  
Gautam Shrikhande ◽  
Lalita Khaodhiar ◽  
Salvatore Scali ◽  
Christina Lima ◽  
Matthew Hubbard ◽  
...  

2015 ◽  
Vol 3 (6) ◽  
pp. e12430 ◽  
Author(s):  
Yu-Sok Kim ◽  
Thomas Seifert ◽  
Patrice Brassard ◽  
Peter Rasmussen ◽  
Allan Vaag ◽  
...  

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