Synthesis of 7-Substituted 5-Oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxylic Acids, 2-Substituted 4-Oxo-4H-pyrido [1,2-a]pyrimidine-3-carboxylic Acids, and 2,6-Disubstituted 4-Quinolones from Meldrum's Acid Derivatives

Synthesis ◽  
1989 ◽  
Vol 1989 (04) ◽  
pp. 317-320 ◽  
Author(s):  
Fang-Chen Ye ◽  
Bang-Chi Chen ◽  
Xian Huang
2003 ◽  
Vol 2003 (3) ◽  
pp. 174-175 ◽  
Author(s):  
V.B. Helavi ◽  
S.B. Solabannavar ◽  
U.V. Desai ◽  
R.B. Mane

Microwave induced hydrolysis of alkyl Medrum's acids and decarboxylation of derived malonic acids using poly-4-vinylpyridine as a catalyst gives high yields of carboxylic acids in a short time.


Author(s):  
Silma Francielle da Silva ◽  
Felipe Anchieta e Silva ◽  
Ana Paula Martins de Souza ◽  
Thenner Silva Rodrigues ◽  
Róbson Ricardo Teixeira

Peptides 1992 ◽  
1993 ◽  
pp. 607-608
Author(s):  
Massimo Pinori ◽  
Silvana Cappelletti ◽  
Andrea Zaliani ◽  
Antonio Silvio Verdini

2020 ◽  
Vol 22 (16) ◽  
pp. 6667-6670
Author(s):  
Felix Brosge ◽  
Johannes Florian Kochs ◽  
Mariela Bregu ◽  
Khai-Nghi Truong ◽  
Kari Rissanen ◽  
...  

Molecules ◽  
2020 ◽  
Vol 25 (9) ◽  
pp. 2178 ◽  
Author(s):  
Cédric Peyrot ◽  
Matthieu M. Mention ◽  
Fanny Brunissen ◽  
Patrick Balaguer ◽  
Florent Allais

Faced with the ban of some organic UV filters such as octinoxate or avobenzone, especially in Hawaii, it became essential to offer new alternatives that are both renewable and safe for humans and the environment. In this context, a class of bio-based molecules displaying interesting UV filter properties and great (photo)stability has been developed from Meldrum’s acid and bio-based and synthetic p-hydroxycinnamic acids, furans and pyrroles. Moreover, p-hydroxycinnamic acid-based Meldrum’s derivatives possess valuable secondary activities sought by the cosmetic industry such as antioxidant and anti-tyrosinase properties. The evaluation of the properties of mixture of judiciously chosen Meldrum’s acid derivatives highlighted the possibility to modulate secondary activity while maintaining excellent UV protection. Meldrum’s acid derivatives are not only competitive when benchmarked against organic filters currently on the market (i.e., avobenzone), but they also do not exhibit any endocrine disruption activity.


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