EP.WE.548The prevalence iron deficiency anaemia in patients with oesophago-gastric cancer

2021 ◽  
Vol 108 (Supplement_7) ◽  
Author(s):  
Catherine McCollum ◽  
Khurram Khan ◽  
Rongkagorn Chuntamongkol ◽  
Matthew Forshaw
Keyword(s):  
Gastric Cancer ◽  
Iron Deficiency ◽  
Iron Deficiency Anaemia ◽  
Iron Level ◽  
Serum Iron Level ◽  
Blood Profile ◽  
Deficiency Anaemia ◽  
Adult Men ◽  
High Prevalence ◽  
Post Menopausal

Abstract Aims Blood loss from the gastrointestinal tract is the most common cause of iron deficiency anaemia (IDA) in adult men and post-menopausal women. Up to 10% of patients with IDA have underlying gastrointestinal cancer. The aim of this study was to investigate prevalence of IDA in patients with oesophago-gastric cancer. Methods A retrospective cohort study of all newly diagnosed oesophago-gastric cancers (adenocarcinoma and squamous cell carcinoma) and high grade dysplasia discussed at tertiary multi-disciplinary team meeting between October 2019 and September 2020. Electronic case notes and blood profile at presentation, including ferritin and serum iron level, were analysed. Patients who did not have blood profile within three months of presentation were excluded. Results A total of 349 patients were identified, 12 were excluded due to missing data. 226 (67.1%) were male and the mean age was 69.7 ± 11.7 years. 260 (77.2%) were referred from primary care. After initial investigations, 256 (76.0%) were oesophageal cancer, 248 (73.6%) were adenocarcinoma, and 134 (39.8%) were metastatic at presentation. 128 (38.0%) patients were anaemic: 30 (23.4%) microcytic, 88 (68.8%) normocytic and 10 (7.8%) macrocytic. 98 (76.6%) anaemic patients had ferritin and/or iron levels checked. Analysis of these identified 63 (49.2%) patients with bloods consistent with IDA: 22 (34.9%) microcytic, 40 (63.5%) normocytic, and 1 (1.6%) macrocytic. Conclusions This study confirms that while there is high prevalence of anaemia in patients presenting with oesophagi-gastric cancer, IDA was diagnosed in only half of these. The predominant form of anaemia identified in these patients is normocytic.

scholarly journals Association between iron deficiency anaemia and simple febrile seizure in South Indian rural population

2020 ◽  
Vol 7 (12) ◽  
pp. 2355
Author(s):  
Gayathri Durai ◽  
Syamily Parambath ◽  
Rajendiran Ramachari Ramayi
Keyword(s):  
Risk Factor ◽  
Iron Deficiency ◽  
Febrile Seizure ◽  
Serum Iron ◽  
Iron Deficiency Anaemia ◽  
Febrile Seizures ◽  
Iron Level ◽  
Serum Iron Level ◽  
Deficiency Anaemia ◽  
South Indian

Background: Simple febrile seizure is a common problem worldwide, many studies have investigated the etiology and natural history of febrile seizures and evaluated various management strategies, but very little information is available about iron deficiency as a risk factor. Hence, we aimed to determine the association between iron deficiency anaemia and simple febrile seizures in south Indian rural population. Methods: It is an observational study done in paediatrics department at Sri Venkateshwaraa medical college hospital and research centre. A total 120 (60 cases and 60 control) were included in the study. Children with febrile seizures and controls were included fever without seizures. Informed consent was taken from parents of each child. Children were divided into two groups, cases and controls. Serum ferritin level, Hb, HCT and MCV levels were assessed.Results: Mean Hb level in cases and controls were 9.1±1.2 and 12.7±1.7 mg/dl respectively. Mean MCV value in cases and controls was 78.1±6.2 and 81.4±6.9 respectively. Mean serum iron level in cases was 29.9±4.9 and in controls mean serum iron level was 42.8±7.4. Conclusions: Iron deficiency anaemia is considered as a risk factor for febrile seizures in children.

scholarly journals The potential effect of iron defortification on iron-deficiency anaemia in the US population

2007 ◽  
Vol 10 (11) ◽  
pp. 1266-1273 ◽  
Author(s):  
Min Tao ◽  
David L Pelletier ◽  
Dennis D Miller
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anaemia ◽  
Iron Status ◽  
Potential Effect ◽  
Reproductive Age ◽  
Iron Nutrition ◽  
Deficiency Anaemia ◽  
Adult Men ◽  
The Us ◽  
The Usa

AbstractObjectiveTo quantify the potential effect of iron defortification in the USA on iron-deficiency anaemia (IDA).MethodsMonte Carlo models were built to simulate iron nutrition in the US population. A hypothetical cohort of 15 000 persons from the general population was used in 15-year simulations to compare the prevalence of IDA with and without fortification.ResultsWith iron fortification, the prevalence of IDA was 2.4% for children aged 3–5 years, 5.4% for women aged 20–49 years, and 0.14% for men aged 20–49 years. The corresponding IDA estimates under iron defortification were 4.5%, 8.2% and 0.46%, respectively. Defortification had little effect on the distribution of iron indicators at or above the 50th percentile within each of these three groups and little effect on the distributions of iron indicators among adult men.ConclusionIron defortification is likely to increase IDA among children and women of reproductive age, but is not likely to have meaningful effects on the iron status of men or the majority of women and children.

Severe iron deficiency anaemia

2013 ◽  
pp. 35-42
Author(s):  
Daniel Marks ◽  
Marcus Harbord
Keyword(s):  
Chronic Disease ◽  
Iron Deficiency ◽  
Blood Loss ◽  
Iron Deficiency Anaemia ◽  
Parasite Load ◽  
Deficiency Anaemia ◽  
Iron Stores ◽  
Menopausal Women ◽  
Post Menopausal ◽  
Developed World

Implication of iron deficiency Causes of iron deficiency Overt or occult bleeding Diagnosing iron deficiency Presentation and investigations Treatment Anaemia of chronic disease In the developed world, the commonest cause of iron deficiency anaemia (IDA) and its prelude iron deficiency is menstrual blood loss. Worldwide, hookworm infection is prevalent and causes IDA in those with heavy parasite load. About 4% of men/post-menopausal women have iron deficiency, and 1–2% have related IDA. Iron deficiency rises to ~20% in pre-menopausal women (remainder often have considerably reduced iron stores)....

Effectiveness of long term community based nutrition intervention for prevention and management of anaemia among adolescent girls

2017 ◽  
Vol 36 (03) ◽  
Author(s):  
K. Grover ◽  
M. Choudhary
Keyword(s):  
Iron Deficiency ◽  
Nutrition Education ◽  
Adolescent Girls ◽  
Iron Deficiency Anaemia ◽  
Nutrition Intervention ◽  
Food Frequency ◽  
Deficiency Anaemia ◽  
High Prevalence ◽  
One Year

High prevalence of iron deficiency anaemia among adolescent girls is a matter of great concern because of double demand of growth and activity. Therefore, the present study was conducted among 200 unmarried adolescent girls(10-18 yrs) with an objective to assess the prevalence of anemia and to improve the dietary behavior and reduce iron deficiency anaemia through nutrition intervention. The effectiveness of nutrition intervention was evaluated through various parameters viz. Body Mass Index (BMI), haemoglobin (Hb) level, food frequency and knowledge, attitude and practice (KAP) scores. Nutrition intervention was imparted to the subjects for a period of one year. Consequently, the average Hb level of the subjects increased significantly (p£0.01) from 8.55 to 10.66 g/dl. A significant (p£0.01) increase in BMI i.e. 17.7 to18.8 Kg/m2 was also found in the selected subjects. Further, Nutrition education also showed a significant improvement (p £0.01) in the food frequency of the entire Hb forming food items as well as KAP scores among adolescent girls.

Iron Deficiency Anaemia Among Children and Pregnant Women in the Arab Gulf Countries: The Need for Action

2002 ◽  
Vol 16 (3) ◽  
pp. 161-171 ◽  
Author(s):  
Abdulrahman O. Musaiger
Keyword(s):  
Iron Deficiency ◽  
Pregnant Women ◽  
Iron Deficiency Anaemia ◽  
Parasitic Infection ◽  
Geographical Location ◽  
Deficiency Anaemia ◽  
Gulf Countries ◽  
High Prevalence ◽  
Arab Gulf ◽  
And Control

Anaemia, especially iron deficiency anaemia, has been considered one of the main public health problems in the Arab Gulf countries. This paper explores the magnitude of the problem and factors that contribute to the high prevalence of anaemia in these countries. The prevalence of iron deficiency anaemia among preschool children ranged from 20% to 67%, while that among school children ranged from 12.6% to 50%. The percentage of pregnant women who suffered from this anaemia ranged from 22.7% to 54%. Infant feeding practices, food habits, parasitic infection, parity, early age at marriage, and geographical location are among the most important factors associated with iron deficiency anaemia in this region. Programmes to prevent and control this anaemia, are urgently needed.

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