scholarly journals Effect of phytase on intestinal phytate breakdown, plasma inositol concentrations, and glucose transporter type 4 abundance in muscle membranes of weanling pigs1

2019 ◽  
Vol 97 (9) ◽  
pp. 3907-3919 ◽  
Author(s):  
Hang Lu ◽  
Imke Kühn ◽  
Mike R Bedford ◽  
Hayley Whitfield ◽  
Charles Brearley ◽  
...  
Keyword(s):  
Growth Performance ◽  
Plasma Membranes ◽  
Glucose Transporter ◽  
Inositol Phosphates ◽  
Block Design ◽  
Positive Control ◽  
Negative Control ◽  
Nursery Pigs ◽  
Longissimus Dorsi Muscle ◽  
Glucose Transporter Type 4

Abstract The objective of this present study was to determine the effects of phytase dosing on growth performance, mineral digestibility, phytate breakdown, and the level of glucose transporter type 4 (GLUT4) in muscle plasma membranes of weanling pigs. A total of 160 barrows were used in a randomized completely block design and assigned to 4 treatments for a 7-wk study. Depending on the feeding phase, diets differed in dietary calcium (Ca) and phosphorus (P) levels (positive control [PC]: 8 to 6.8g/kg Ca; 7.3 to 6.3 g/kg P; negative control [NC]: 5.5 to 5.2 g/kg Ca; 5.4 to 4.7 g/kg P). NC diets were supplemented with phytase at 0 (NC); 500 (NC + 500 FTU); or 2,000 FTU/kg (NC + 2,000 FTU) phytase units/kg. Blood was collected after fasting (day 48) or feeding (day 49) for measurement of plasma inositol concentrations. On day 49, 2 pigs per pen were euthanized, and duodenal and ileal digesta samples were collected to determine inositol phosphates (InsP6-2) concentrations. High phytase supplementation increased BW on days 21, 35, and 49 (P < 0.05). Over the entire feeding period, ADG, ADFI, and feed efficiency were increased by NC + 2,000 FTU compared with the other treatments (P < 0.05). Postprandial plasma inositol concentration was increased in NC + 2,000 (P < 0.01), but there was only a tendency (P = 0.06) of a higher fasting plasma inositol concentration in this group. Inositol concentrations in the portal vein plasma (day 49) were not different among treatments. Duodenal digesta InsP5 and InsP6 concentrations were similar in PC and NC, but higher in these 2 treatments (P < 0.05) than those supplemented with phytase. Phytase supplementation decreased InsP6-4, resulting in increased InsP3-2 and myo-inositol concentrations. Similar effects were found in ileal contents. Compared with NC, phytase supplementation resulted in greater cumulative InsP6-2 disappearance (93.6% vs. 72.8% vs. 25.0%, for NC + 2,000 FTU, NC + 500 FTU and NC, respectively, P < 0.01) till the distal ileum. Longissimus dorsi muscle plasma membrane GLUT4 concentration was increased by NC + 2,000 FTU (P < 0.01) compared with NC. In summary, high phytase supplementation increased growth performance of nursery pigs. The higher myo-inositol release from phytate could contribute to the increased expression of GLUT4 in muscle plasma membranes. Further investigation is needed to determine whether this is associated with enhanced cellular glucose uptake and utilization.

scholarly journals 178 Efficacy of commercial products on growth performance of nursery pigs fed diets with fumonisin-contaminated corn

2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 78-79
Author(s):  
Zhong-Xing Rao ◽  
Mike D Tokach ◽  
Steve S Dritz ◽  
Jason C Woodworth ◽  
Joel M DeRouchey ◽  
...  
Keyword(s):  
Growth Performance ◽  
Wide Spectrum ◽  
Block Design ◽  
Control Diet ◽  
Positive Control ◽  
Negative Control ◽  
Experimental Unit ◽  
Negative Effects ◽  
Commercial Products ◽  
Nursery Pigs

Abstract Two experiments were conducted to determine the efficacy of commercial products on growth performance of nursery pigs fed high fumonisin diets. In Exp. 1,350 pigs (241 × 600; DNA; initially 9.9 kg) were used with 5 pigs per pen and 14 pens per treatment. Five dietary treatments consisted of a positive control (low fumonisin, 4 ppm fumonisin; FB1 + FB2), negative control (50 ppm fumonisin;) and the negative control with one of three products (0.3% of Kallsil Dry, Kemin Industries Inc., Des Moines, IA; 0.3% of Feed Aid Wide Spectrum, NutriQuest, Mason City, IA; 0.17% of Biofix Select Pro, Biomin America Inc., Overland Park, KS). Diets were fed for 14 d. Pens were assigned to treatments in a randomized complete block design with initial weight as the blocking factor. Data were analyzed using nlme package in R program (version 3.5.2) with pen as experimental unit. Pigs fed the negative control, or diets with Kallsil Dry or Feed Aid had decreased (P&lt; 0.05) ADG, ADFI, and G:F compared with those fed the positive control and diet with Biofix. Pigs fed the positive control diet had decreased (P&lt; 0.05) d 14 serum sphinganine to sphingosine (Sa:So) ratio than those fed other diets. In Exp. 2, 300 pigs (241 × 600; initially 10.4 kg) were used and fed experimental diets for 28 d. Procedures were similar to Exp. 1 except there were 12 replicates per treatment and diets contained 30 ppm fumonisin. Pigs fed the negative control, or diets with Kallsil Dry or Feed Aid had decreased (P&lt; 0.05) ADG and G:F, and greater (P&lt; 0.05) d 14 and 28 Sa:So ratios compared with the positive control and diet with Biofix. In summary, adding Biofix to high fumonisin diets mitigated the negative effects of fumonisin while Kallsil Dry and Feed Aid did not.

20 Effect of Adding Bioactive Peptide in Combination of Pharmaceutical Zinc Oxide or Organic Acids on Growth Performance, Hematology Profile, and Nutrient Digestibility in Nursery Pigs

2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 22-23
Author(s):  
Richard A Mudarra ◽  
Tsung Cheng Cheng Tsai ◽  
Kristopher Bottoms ◽  
Thomas S Shieh ◽  
Casey Bradly ◽  
...  
Keyword(s):  
Growth Performance ◽  
Phase 1 ◽  
Random Effect ◽  
Positive Control ◽  
Negative Control ◽  
Nutrient Digestibility ◽  
Bioactive Peptide ◽  
Nursery Pigs ◽  
Cell Counts ◽  
High Zinc

Abstract To evaluate the effect of bioactive peptide (P) in combination with high level of zinc (HZ) or acidifiers on growth performance, complete blood cell counts (CBC) and nutrient digestibility in nursery pigs, a total of 288 weaned pigs (PIC1050xDNA600) were stratified by initial BW within gender and allotted to 1of 7 treatments. Treatments for phase 1&2 were: 1) nutrient adequate positive control with HZ (PC), 2) nutrient deficient negative control with HZ (NC, -0.13% SID Lysine by reducing fish meal), 3) NC+0.25% peptide (0.25PZ), 4) NC+0.5% peptide (0.5PZ), 5) NC+0.25% peptide with standard zinc (0.25P), 6) NC+0.5% peptide with standard zinc (0.5P), 7) as 5 + 0.1% sodium butyrate and 0.5% benzoic acid (PSB). All pigs were fed a common low Zn diet (197 ppm) during phase 3. The whole blood was obtained from a close-to-average pen-BW pig repeatedly at weaning, and at the end of phase 2 and 3 to determine CBC. Titanium dioxide was used as an indigestible marker to determine nutrient digestibility. Data were analyzed using the Mixed procedures of SAS as a RCBD with treatment as fixed effect, and BW block as random effect. In overall phase 1&2, pigs fed PSB had similar ADG and BW when compared to pigs fed 0.25PZ and both were greater than NC pigs (Table 1). With the same inclusion rate of peptide, pigs fed a high zinc diet had greater BW and ADG than pigs fed a standard zinc diet. PSB pigs had the greatest G:F ratio and nitrogen digestibility among treatments. Increasing peptide in high zinc diets gradually decreased Neutrophil-to-lymphocyte ratio. This study indicates that the improvement in growth performance from pigs fed peptide is pharmaceutical zinc dependent and acidifiers can be an alternative to replace ZnO without affecting growth performance.

scholarly journals PSV-10 Effects of storing three phytase sources for 90 days under high temperature and humidity on phytase stability, growth performance, and bone mineralization of nursery pigs

2019 ◽  
Vol 97 (Supplement_2) ◽  
pp. 194-195
Author(s):  
Carine M Vier ◽  
Mariana Boscato Menegat ◽  
Kiah M Gourley ◽  
Steve S Dritz ◽  
Mike D Tokach ◽  
...  
Keyword(s):  
High Temperature ◽  
Growth Performance ◽  
Bone Mineralization ◽  
Positive Control ◽  
Negative Control ◽  
Phytase Activity ◽  
Pure Form ◽  
Nursery Pigs ◽  
Bone Ash ◽  
Nursery Pig

Abstract This study evaluated storing 3 commercial phytases for 90 d in an environmental chamber set at 29.4°C and 75% humidity on phytase stability and nursery pig growth performance and bone mineralization. The phytases [HiPhos GT (20,000 FYT/g, DSM Nutritional Products, Parsippany, NJ); Axtra Phy TPT (20,000 FTU/g, Dupont, Wilmington, DE), and Quantum Blue G (40,000 FTU/g, AB Vista, Plantation, FL)] were kept as pure forms or blended in a vitamin-trace mineral (VTM) premix and sampled on d 0, 30, 60, and 90 of storage. Regardless of source and form, analyzed phytase activity decreased (linear, P < 0.001) as storage increased. Afterwards, 300 nursery pigs (11.7 kg BW) were assigned to 1 of 8 treatments in a RCBD with 4-5 pigs/pen and 8 pens/treatment. Treatments included a negative (NC, 0.12% aP) and positive control (PC, 0.27% aP) without phytase; or NC with added phytase to provide 0.15% aP (1,000, 651 and 500 FTU/kg for HiPhos, Axtra Phy, and Quantum Blue, respectively). Negative control with added phytase treatments were manufactured with each phytase source previously stored in pure form or VTM premix for 90d. Pigs fed PC had greater (P < 0.001) ADG compared to pigs fed Axtra Phy stored in VTM or NC. Feed intake was similar for PC, phytases stored in pure forms, and HiPhos and Quantum Blue stored in VTM, and greater (P < 0.001) than pigs fed NC. Pigs fed PC or HiPhos stored in pure form had improved (P < 0.001) G:F compared to pigs fed NC. Bone mineralization was greater (P < 0.001) for pigs fed PC compared to NC, phytases stored in VTM, and Axtra Phy and Quantum Blue stored in pure form. Regardless of source and form, phytase activity decreased as storage increased. In this study, bone ash was reduced when phytases were stored for 90d in a VTM compared to the PC.

scholarly journals Inclusion of the direct-fed microbial Clostridium butyricum in diets for weanling pigs increases growth performance and tends to increase villus height and crypt depth, but does not change intestinal microbial abundance

2019 ◽  
Vol 98 (1) ◽  
Author(s):  
Gloria A Casas ◽  
Laia Blavi ◽  
Tzu-Wen L Cross ◽  
Anne H Lee ◽  
Kelly S Swanson ◽  
...  
Keyword(s):  
Growth Performance ◽  
Block Design ◽  
Control Diet ◽  
Positive Control ◽  
Negative Control ◽  
Clostridium Butyricum ◽  
Weanling Pigs ◽  
Villus Height ◽  
Weaned Pigs ◽  
Crypt Depth

Abstract An experiment was conducted to test the hypothesis that inclusion of the direct fed microbial Clostridium butyricum in diets for weanling pigs will improve growth performance, systemic immune function, microbiota composition, and gut morphology in weaned pigs. A total of 275 newly weaned pigs (20 ± 2 d of age) with an average initial BW of 6.4 ± 0.8 kg were allotted to a randomized complete block design with 11 pens per treatment. Diets included a positive control diet containing Carbadox, a negative control diet without Carbadox, and three treatment diets in which 1,250 × 108 cfu/kg, 2,500 × 108 cfu/kg, or 3,500 × 108 cfu/kg of C. butyricum was added to the negative control diet. A two-phase feeding program was used (phase 1, 14 d; phase 2, 21 d). At the conclusion of the experiment (day 35), a blood sample was collected from one pig per pen (11 pigs per treatment) and this pig was then euthanized and digesta and tissues samples were collected. Results indicated that for the overall phase, pigs fed the positive control diet had greater (P &lt; 0.05) ADG and ADFI and tended (P = 0.064) to have greater final BW than pigs fed the negative control diet. The ADG and G:F increased and then decreased as increasing doses of C. butyricum were included in the diet (quadratic, P &lt; 0.05). The concentration of tumor necrosis factor-α was less (P &lt; 0.05) in pigs fed the positive control diet compared with pigs fed the negative control diet or diets containing C. butyricum. Crypt depth tended (P = 0.08) to be less in pigs fed the negative control diet compared with pigs fed the positive control diet and villus height tended to increase as the doses of C. butyricum increased in the diets (quadratic, P = 0.08). Villus height also tended (P = 0.084) to be greater in pigs fed diets containing C. butyricum compared with pigs fed the positive control diet. Crypt depth increased as the dose of C. butyricum increased (quadratic, P &lt; 0.05) and villus width at the bottom tended to increase (linear, P = 0.072) as the dose of C. butyricum increased in the diet. Alpha and beta diversity indices of ileal and colonic microbiota were not affected by diet. In conclusion, addition of 1,250 × 108 cfu/kg of C. butyricum, but not greater levels, to diets fed to weanling pigs increased growth performance and tended to increase villus height and crypt depth, but changes in the abundance of intestinal microbiota were not observed.

scholarly journals 123 Growth performance and nutrient digestibility of multi-enzyme-supplemented low-energy and -amino acid diets for growing and finishing pigs

2019 ◽  
Vol 97 (Supplement_2) ◽  
pp. 69-70
Author(s):  
Kevin S Jerez Bogota ◽  
Christian Sanchez ◽  
Jimena Ibagon ◽  
Maamer Jlali ◽  
Pierre Cozannet ◽  
...  
Keyword(s):  
Growth Performance ◽  
Block Design ◽  
Phase 1 ◽  
Positive Control ◽  
Negative Control ◽  
Nutrient Digestibility ◽  
Growing Pigs ◽  
Finishing Pigs ◽  
P Content ◽  
Randomized Complete Block Design

Abstract Objective was to determine the effects of supplementing corn-soybean meal-based diets with a multi-enzyme on growth performance and apparent total tract digestibility (ATTD) of nutrients in growing pigs. A total of 276 pigs (BW = 33.99 ± 4.3 kg) were housed by sex in 45 pens of 6 or 7 pigs and fed 5 diets (9 pens/diet) in a randomized complete block design. Diets were positive control (PC); and negative control 1 (NC1) or negative control 2 (NC2) without or with multi-enzyme. The multi-enzyme used supplied at least 1,250, 860, 4,600, and 1,000 units of xylanase, β-glucanase, arabinofuranosidase and phytase per kilogram of diet, respectively. The PC was adequate in all nutrients according to NRC (2012) recommendations and had greater digestible P content than NC1 diet or NC2 diet by 0.134 percentage points. The NC1 diet had lower NE and digestible AA content than PC diet by 3%. The NC2 diet had lower NE and digestible AA content than PC diet by 5%. The diets were fed in 4 phases based on BW; Phase 1: 34–50 kg, Phase 2: 50–75 kg, Phase 3: 75–100 kg, and Phase 4: 100–120 kg. Nutrient digestibility was determined at the end of Phase 1. Overall (34–120 kg BW), pigs fed the PC and NC1 diets did not differ in ADG and ADFI. Pigs fed NC2 diet had lower (PPPP > 0.10). Supplemental multi-enzyme increased (P = 0.047) the ATTD of GE for NC2 diet. In conclusion, the NE and digestible AA and P can be lowered by ≤ 5% in multi-enzyme-supplemented diets without effects on growth performance pigs.

PSXVI-29 Late-Breaking: Effect of dietary organic acids supplementation on growth performance, nutrient digestibility, and gut health in weaned pigs

2021 ◽  
Vol 99 (Supplement_3) ◽  
pp. 383-383
Author(s):  
Jinyoung Lee ◽  
Jong Woong Kim ◽  
Heidi Hall ◽  
Martin Nyachoti
Keyword(s):  
Growth Performance ◽  
Block Design ◽  
Phase 1 ◽  
Positive Control ◽  
Negative Control ◽  
Nutrient Digestibility ◽  
Gut Health ◽  
Weaned Pigs ◽  
Positive Effects ◽  
Two Phases

Abstract This study was conducted to investigate the effects of dietary supplementation with different organic acid (OA) mixtures on growth performance, nutrient digestibility, and gut health in weaned pigs. A total of 56 weaned pigs (7.93 ± 1.04 kg BW) were assigned to 4 dietary treatments in a randomized complete block design with 7 replicates per treatment for a 35-d study conducted over two phases; phase 1 (d 1 to 14) and phase 2 (d 14 to 35). Each pen had two pigs balanced for sex. Diets consisted of 1) a corn-soybean meal-basal without any additive (negative control, NC); 2) NC + formic and propionic acids (TRT1); 3) NC + butyric, formic, and propionic acids (TRT2); and 4) NC + antibiotic (positive control, PC). Individual pig body weight and feed disappearance were recorded weekly. At the end of each phase, blood and feces were sampled. The female pig in each pen was euthanized on d 35 to collect digesta and intestinal tissue. Data were analyzed using the PROC MIXED of SAS. During the overall period, ADG tended to be lower (P = 0.069) in the TRT2 group than in the PC group. Diet had no effect on ADFI during the overall period, but G:F of pigs fed the PC and TRT1 diets tended to be higher (P = 0.059) than that of the NC diet. No effects of OA supplementation were observed on nutrient digestibility and blood cytokine. Jejunal villus height to crypt depth ratio was higher (P &lt; 0.05) in TRT1-fed pigs than that of NC-fed pigs. Pigs fed the TRT2 diet had a higher (P &lt; 0.05) fecal abundance of Bifidobacteria than those fed the PC diet in phase 1. In conclusion, dietary OA supplementation had positive effects on growth performance and gut health but no effect on nutrient digestibility in weaned pigs.

scholarly journals 80 Determining the effects of tryptophan biomass on growth performance of 11 to 23 kg nursery pigs

2019 ◽  
Vol 97 (Supplement_2) ◽  
pp. 43-43
Author(s):  
Madison R Wensley ◽  
Jason C Woodworth ◽  
Joel M DeRouchey ◽  
Steve S Dritz ◽  
Mike D Tokach ◽  
...  
Keyword(s):  
Block Design ◽  
Positive Control ◽  
Negative Control ◽  
Experimental Unit ◽  
Growth Data ◽  
Nursery Pigs ◽  
Nursery Pig ◽  
Pig Performance ◽  
Dietary Treatments ◽  
Growth Trial

Abstract A total of 320 barrows (DNA 200×400, initially 11.3 ± 0.65 kg BW) were used in a 21-d growth trial evaluating the effects of feeding Trp biomass (CJ America-Bio, Downers Grove, IL) as a source of Trp on nursery pig performance. Pigs were weaned at approximately 21 d of age, placed in pens based on initial BW, and fed a common diet. On d 21 after weaning, pigs were weighed and pens were allotted to 1 of 4 dietary treatments with 5 pigs/pen and 16 replicates/treatment. Dietary treatments included a negative control (16% SID Trp:Lys), positive control (21% SID Trp:Lys from crystalline L-Trp), or diets containing Trp biomass to provide 21 or 23.5% SID Trp:Lys (included at 0.104 or 0.156% of the diet, respectively). Diets were corn-soybean meal based and contained 1.25% SID Lys with other AA set to meet or exceed NRC (2012) requirement estimates. The Trp biomass contained 69% Trp. Growth data were analyzed as a randomized complete block design using PROC GLIMMIX of SAS with pen as the experimental unit. Overall (d 0 to 21) pigs fed 21% Trp from L-Trp or Trp biomass had increased (P < 0.05) ADG compared to the control, with pigs fed the 23.5% SID Trp biomass intermediate. Pigs fed the 21% Trp from Trp biomass had improved (P < 0.05) G:F compared to the control with others intermediate. In conclusion, Trp biomass is a viable alternative to crystalline Trp, but further evaluation at higher inclusion levels is needed.

scholarly journals 176 Evaluation of a novel threonine source for nursery pig diets

2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 85-86
Author(s):  
Dalton Humphrey ◽  
Spenser Becker ◽  
Jason Lee ◽  
Keith Haydon ◽  
Laura L Greiner
Keyword(s):  
Growth Performance ◽  
Positive Control ◽  
Negative Control ◽  
Experimental Unit ◽  
Nursery Pigs ◽  
Nursery Pig ◽  
Weaning Pigs ◽  
Dietary Treatments ◽  
Similar Growth ◽  
Source Test

Abstract Four hundred and eighty (PIC 337 X 1050, PIC Genus, Hendersonville, TN) pigs were used to evaluate a novel threonine source (ThrPro, CJ America-Bio, Fort Dodge, IA) for nursery pigs from approximately 7 kg to 20 kg. At weaning, pigs were sorted by gender and fed a common diet for one week. Upon completion of the first week, pigs were sorted into randomized complete blocks, equalized by weight, within 16 replications. Pigs were allocated to one of three dietary treatments: positive control (POS)-SID LYS:THR 0.60, negative control (NEG)-SID LYS:THR ≤0.46 and alternative threonine source (TEST)-SID LYS:THR 0.60. All other nutrients met or exceeded the NRC (2012) recommendations. Growth and intake data were analyzed using PROC MIXED procedure in SAS. The experimental unit was the pen. During the first 14 days, pigs fed TEST had similar ADG (0.417 vs. 0.414 kg/d, P=0.81) and G:F (0.977 vs. 1.030, P=0.18) compared to POS, and increased ADG (0.417 vs. 0.387 kg/d, P=0.01) and G:F (0.977 vs. 0.898, P=0.05) compared to NEG. Over days 14-28, pigs fed TEST had similar ADG (0.523 vs. 0.532 kg/d, P=0.49) and G:F (0.712 vs. 0.707, P=0.71) compared to POS, and increased ADG (0.523 vs. 0.479 kg/d, P=0.002) and G:F (0.712 vs. 0.627, P&lt; 0.0001) compared to NEG. Overall (d 0 to 28), pigs fed TEST had similar ADG (0.466 vs. 0.474 kg/d, P=0.48) and G:F (0.808 vs. 0.816, P=0.55) compared to POS, and increased ADG (0.466 vs. 0.433 kg/d, P=0.002) and G:F (0.808 vs. 0.725, P&lt; 0.0001) compared to NEG. ADFI was not significantly different across treatments for the entirety of the study. In conclusion, the replacement of L-threonine with a novel threonine source resulted in similar growth performance in nursery pigs from approximately 7 kg to 20 kg.

185 The Impacts of Commercial Dietary Acidifiers on Growth Performance of Nursery Pigs

2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 87-87
Author(s):  
Payton L Dahmer ◽  
Cassandra K Jones
Keyword(s):  
Growth Performance ◽  
Block Design ◽  
Phase 1 ◽  
Dietary Treatment ◽  
Negative Control ◽  
Experimental Unit ◽  
Nursery Pigs ◽  
Commercial Diet ◽  
Randomized Block Design ◽  
Pig Performance

Abstract A total of 360 weanling pigs (DNA 200 x 400; initially 9.7 ± 0.23 kg BW) were used in a 21-d growth trial to evaluate the effects of commercial diet acidifiers in nursery diets. Upon weaning, pigs were weighed and allotted to pens (6 pigs/pen, 10 replicate pens/treatment, blocked by 2 separate nursery rooms) and pens were then randomly assigned to one of 6 treatment diets: 1) negative control (no antibiotics or acidifiers) and the control with 2) 0.25% Acidifier A (KEM-GEST™, Kemin Industries, Des Moines, IA); 3) 0.3% Acidifier B (ACITVATE® DA, Novus International, Saint Charles, MO); 4) 0.5% Acidifier C (OutPace®, PMI Additives, Arden Hills, MN); 5) 50 g/ton carbadox; 6) 400 g/ton chlortetracycline. Pigs were fed common phase 1 and phase 2 starter diets without antimicrobials for 21 days, then fed experimental diets for 21 days. Data were analyzed as a completely randomized block design with pen as the experimental unit. Dietary treatment significantly impacted (P &lt; 0.05) all growth response criteria for each week of the experiment. Overall (d 0 to 21), ADG was the greatest (P &lt; 0.0001) for pigs fed a diet containing CTC. Likewise, ADFI was increased (P &lt; 0.0001) for pigs consuming CTC compared to those fed the negative control, acidifier A, acidifier B and carbadox diets, while those fed acidifier C were intermediate. Feed efficiency was poorest (P &lt; 0.0001) in pigs fed a diet with carbadox. By the end of the experiment, pigs fed CTC were significantly heavier (P &lt; 0.0001) than pigs fed all remaining treatments. In summary, feeding CTC improved nursery pig performance while carbadox unexpectedly reduced it. The addition of dietary acidifiers did not improve growth performance compared to a negative control.

PSVI-4 Effect of phytase on mineral digestibility and growth performance of pigs fed diets with pharmacological levels of Zn

2021 ◽  
Vol 99 (Supplement_3) ◽  
pp. 400-401
Author(s):  
Charmaine D Espinosa ◽  
Deepak Velayudhan ◽  
Yueming Dersjant-Li ◽  
Janet Remus ◽  
Hans-Henrik H Stein
Keyword(s):  
Growth Performance ◽  
Block Design ◽  
Average Daily Gain ◽  
Positive Control ◽  
Negative Control ◽  
Metabolizable Energy ◽  
Randomized Complete Block Design ◽  
Quadratic Effects ◽  
Digestible Amino Acids ◽  
Daily Gain

Abstract An experiment was conducted to test the hypothesis that increasing levels of phytase increases mineral digestibility and growth performance of pigs fed diets with 3,000 mg/kg of Zn. A positive control (PC) diet that met nutrient requirements and a negative control (NC) diet that was deficient in total Ca (-0.16%), digestible P (-0.14%), metabolizable energy (-50 kcal/kg), and digestible amino acids (-0.02%) were formulated. Eight additional diets were formulated by adding 500, 1,000, 1,500, or 2,000 phytase units/kg of a novel bacterial 6-phytase (PhyG) or a commercial Buttiauxella phytase (PhyB) to the NC diet. A randomized complete block design with 400 weanling pigs (5.82 ± 0.70 kg), 10 diets, 4 pigs per pen, and 10 replicate pens per diet was used. Pigs were fed the experimental diets for 28 d. Fecal samples were collected from 1 pig per pen on d 26 to 28. Linear and quadratic effects of PhyG and PhyB were determined using polynomial contrast statements. Contrast statements were used to compare effects of PC diet with NC diet, and to compare effects of PhyG diets with PhyB diets. Overall, pigs fed the NC diet had reduced growth performance (P &lt; 0.05) compared with pigs fed the NC diet (Table 1). Linear (P &lt; 0.01) and quadratic (P &lt; 0.05) increases in overall average daily gain and average daily feed intake of pigs were observed as dietary concentrations of PhyG or PhyB increased. Increasing levels of PhyG or PhyB linearly increased (P &lt; 0.01) the apparent total tract digestibility (ATTD) of P and Ca. PhyG increased ATTD of P more (P &lt; 0.05) than PhyB. In conclusion, both phytases are effective in increasing mineral digestibility and growth performance in pigs fed diets with pharmacological levels of Zn; however, PhyG improved P digestibility more than PhyB.

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