scholarly journals In vivo Generation of Functional Tissues using the Inkjet Printing Technology

2008 ◽  
Vol 22 (S1) ◽  
Author(s):  
Tao Xu ◽  
John Olson ◽  
Weixin Zhao ◽  
Anthony Atala ◽  
Jian-Ming Zhu ◽  
...  

We report the use of a high resolution magnetic resonance (MR) imaging technique to monitor the development and maturation of tissue-printed constructs in vivo. Layer-by-layer inkjet printing technology was used to fabricate three different tissue constructs on alginate∕collagen gels: bovine aortic endothelial cell-printed (to represent soft tissue), human amniotic fluid-derived stem cell-printed (to represent hard tissue as they underwent osteogenic differentiation in vivo), and cell-free constructs (scaffold only). The constructs were subcutaneously implanted into athymic mice and regularly monitored using a 7T magnetic resonance imaging (MRI) scanner. The three tissue construct types showed distinct image contrast characteristics due to the different tissue microstructures and biochemical compositions at various time points. In addition, changes in tissue microvasculature were examined with dynamic perfusion MRI. These results indicate that high resolution MRI is a promising method for noninvasive, long-term monitoring of the status of cell-printed construct growth, differentiation, and vascularization.


2012 ◽  
Vol 2012 ◽  
pp. 1-11 ◽  
Author(s):  
Yahiea Al-Naiemy ◽  
Taha A. Elwi ◽  
Haider R. Khaleel ◽  
Hussain Al-Rizzo

We present a systematic approach for producing microstrip antennas using the state-of-the-art-inkjet printing technique. An initial antenna design based on the conventional square patch geometry is adopted as a benchmark to characterize the entire approach; the procedure then could be generalized to different antenna geometries and feeding techniques. For validation purposes, the antenna is designed and simulated using two different 3D full-wave electromagnetic simulation tools: Ansoft’s High Frequency Structure Simulator (HFSS), which is based on the Finite Element Method (FEM), and CST Microwave Studio, which is based on the Finite Integration Technique (FIT). The systematic approach for the fabrication process includes the optimal number of printed layers, curing temperature, and curing time. These essential parameters need to be optimized to achieve the highest electrical conductivity, trace continuity, and structural robustness. The antenna is fabricated using Inkjet Printing Technology (IJPT) utilizing Sliver Nanoparticles (SNPs) conductive ink printed by DMP-2800 Dimatix FujiFilm materials printer.


2015 ◽  
Vol 24 (2) ◽  
pp. 119-123
Author(s):  
Ji Won Kye ◽  
Dong Cheul Han ◽  
Han Jae Shin ◽  
HeonGon Kim ◽  
Wanghoon Lee

2017 ◽  
Vol 64 (10) ◽  
pp. 7749-7757 ◽  
Author(s):  
Inaki Ortego-Isasa ◽  
Kami Pars Benli ◽  
Felix Casado ◽  
Juan Ignacio Sancho ◽  
Daniel Valderas

2018 ◽  
Vol 15 (11/12) ◽  
pp. 998
Author(s):  
Ngan Nguyen Le ◽  
Hue Cam Thi Phan ◽  
Huong Kim Tran ◽  
Dung My Thi Dang ◽  
Chien Mau Dang

2018 ◽  
Vol 934 ◽  
pp. 129-133 ◽  
Author(s):  
Chao Fan Lv ◽  
Li Ya Zhu ◽  
Jian Ping Shi ◽  
Zong An Li ◽  
Wen Lai Tang ◽  
...  

Three-dimensional (3D) printing has been playing an important role in diverse areas in medicine. In order to promote the development of tissue engineering, this study attempts to fabricate tissue engineering scaffolds using the inkjet printing technology. Sodium alginate, exhibiting similar properties to the native human extracellular matrix (ECM), was used as bioink. The jetted fluid of sodium alginate would be gelatinized when printed into the calcium chloride solution. The characteristics of the 3D-printed sodium alginate scaffold were systematically measured and analyzed. The results show that, the pore size, porosity and degradation property of these scaffolds could be well controlled. This study indicates the capability of 3D bioprinting technology for preparing tissue engineering scaffolds.


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