COMPARISON OF BLOOD PRESSURE VARIABILITY BETWEEN 24H AMBULATORY MONITORING AND OFFICE BLOOD PRESSURE IN DIABETICS AND NON-DIABETIC PATIENTS A CROSS-SECTIONAL STUDY

Objectives. The concept now emerging is that higher thyroid-stimulating hormone (TSH) and lower thyroid hormone levels within the euthyroid range may adversely affect atherosclerosis. The present study aimed to investigate the potential associations between thyroid parameters and hyperhomocysteinaemia in a cohort of euthyroid diabetic subjects.Material and Methods. Two hundred and seventy-three euthyroid diabetic subjects (167 males and 106 females) were consecutively recruited in this cross-sectional study. Clinical and biomedical data was collected.Results. TSH level was higher in females than males. Compared to normal-homocysteine group, hyperhomocysteinaemia group was more likely to be elderly, males, with longer diabetes history, and with lower diastolic blood pressure. Free thyroxine (FT4) level was lower in hyperhomocysteinaemia group than in normal-homocysteine group; however, it was not statistically significant. Adjusted for age, sex, body mass index, duration of diabetes, blood pressure, fasting glucose, total cholesterol, and triglyceride in logistic regression analyses, hyperhomocysteinaemia was significantly correlated with FT4 (P=0.021). No significant association was found with TSH or free triiodothyronine. When analyzed in subjects with TSH < 2.5 uIU/mL separately, we got similar results.Conclusions. In conclusion, we identified a relation between hyperhomocysteinemia and FT4 in a group of euthyroid diabetic patients.

Download Full-text

Cross-sectional study of the association between day-to-day home blood pressure variability and visceral fat area measured using the dual impedance method

PLoS ONE ◽

10.1371/journal.pone.0206945 ◽

2018 ◽

Vol 13 (11) ◽

pp. e0206945 ◽

Cited By ~ 1

Author(s):

Junko Kuwabara ◽

Koichiro Kuwahara ◽

Yoshihiro Kuwabara ◽

Shinji Yasuno ◽

Yasuaki Nakagawa ◽

...

Keyword(s):

Blood Pressure ◽

Visceral Fat ◽

Blood Pressure Variability ◽

Cross Sectional Study ◽

Home Blood Pressure ◽

Impedance Method ◽

Sectional Study ◽

Visceral Fat Area ◽

Cross Sectional

Download Full-text

The relationship between ambulatory blood pressure variability and enlarged perivascular spaces: a cross-sectional study

BMJ Open ◽

10.1136/bmjopen-2016-015719 ◽

2017 ◽

Vol 7 (8) ◽

pp. e015719 ◽

Cited By ~ 16

Author(s):

Shuna Yang ◽

Wei Qin ◽

Lei Yang ◽

Huimin Fan ◽

Yue Li ◽

...

Keyword(s):

Blood Pressure ◽

White Matter ◽

Ambulatory Blood Pressure ◽

Blood Pressure Variability ◽

Cross Sectional Study ◽

Perivascular Spaces ◽

Spearman Correlation ◽

Sectional Study ◽

Cross Sectional ◽

The Relationship

ObjectivesRecent studies reported that 24-hour ambulatory blood pressure variability (ABPV) was associated with lacunar infarction and white matter hyperintensities (WMH). However, the relationship between ABPV and enlarged perivascular spaces (EPVS) has not been investigated. Thus, our study aimed to investigate whether ABPV is associated with EPVS by 24-hour ambulatory blood pressure monitoring (ABPM).DesignWe conducted this study as a cross-sectional study.SettingsThe study was based on patients who presented for physical examinations in our hospital from May 2013 to June 2016.ParticipantsPatients with both brain MRI scans and 24-hour ABPM were included and patients with acute stroke, a history of severe stroke and some other severe diseases were excluded. A total of 573 Chinese patients were prospectively enrolled in this study.Primary and secondary outcome measuresEPVS in basal ganglia (BG) and white matter (WM) were identified on MRI and classified into three categories by the severity. WMH were scored by the Fazekas scale. Coefficient of variation (CV) and SD were considered as metrics of ABPV. Spearman correlation analysis and ordinal logistic regression analysis were used to assess the relationship between ABPV and EPVS.ResultsThere were statistical differences among the subgroups stratified by the severity of EPVS in BG in the following ABPV metrics: SD and CV of systolic blood pressure (SBP), CV of diastolic blood pressure (DBP) in 24 hours, daytime and nighttime and SD of DBP in nighttime. The above ABPV metrics were positively associated with the degree of EPVS. The association was unchanged after adjusting for confounders. Spearman correlation analysis showed ABPV was not related to the degree of EPVS in the WM.ConclusionABPV was independently associated with EPVS in BG after controlling for blood pressure, but not in the WM. Pathogenesis of EPVS in BG and WM might be different.

Download Full-text

Management and treatment patterns of diabetes patients having blood pressure complications living in Dhaka city, Bangladesh

Asian Journal of Medical and Biological Research ◽

10.3329/ajmbr.v2i3.30118 ◽

2016 ◽

Vol 2 (3) ◽

pp. 458-463

Author(s):

AHM Mahmudur Rahman ◽

Lutful Haque Saran ◽

Md Mamun Ur Rashid ◽

Adnan Taher

Keyword(s):

Blood Pressure ◽

Cross Sectional Study ◽

Treatment Patterns ◽

Diabetic Patients ◽

Survey Questionnaire ◽

Dhaka City ◽

Sectional Study ◽

Cross Sectional ◽

Almost All ◽

Diabetes Patients

A study way carried out in Dhaka city to find out the management and treatment patterns of diabetic patients those having blood pressure complications. It was a cross sectional study of 150 patients by using self administered survey questionnaire and founded data was analyzed and described. In this study, it is found that almost all of the patients (92%) were from Dhaka and just were a few those were outsider but came as referred patients. The male and female percentages were accordingly 64.67% and 35.33% and among those diabetes patients 47.33% had hypertension and 10.66% had hypotension and most of them (74%) check their diabetes monthly. Among those patients 79.33% patients were prescribed only drugs while 17% patients were prescribed to change their routine only and 4% were prescribed both (drug and routine). Most of the diabetes patients having blood pressure complicacy were prescribed only drugs which is very significant and those are going to do further research in this aspect will be benefited by getting this information.Asian J. Med. Biol. Res. September 2016, 2(3): 458-463

Download Full-text

Impact of body mass index on long-term blood pressure variability: a cross-sectional study in a cohort of Chinese adults

BMC Public Health ◽

10.1186/s12889-018-6083-4 ◽

2018 ◽

Vol 18 (1) ◽

Cited By ~ 11

Author(s):

Haojia Chen ◽

Ruiying Zhang ◽

Qiongbing Zheng ◽

Xiuzhu Yan ◽

Shouling Wu ◽

...

Keyword(s):

Blood Pressure ◽

Body Mass Index ◽

Body Mass ◽

Blood Pressure Variability ◽

Cross Sectional Study ◽

Sectional Study ◽

Chinese Adults ◽

Cross Sectional

Download Full-text

Microalbuminuria in Type 2 Diabetic Patients: A Cross-Sectional Study of Frequency, Sex Distribution and Relation to Hypertension

Annals of Clinical Biochemistry International Journal of Laboratory Medicine ◽

10.1177/000456329403100208 ◽

1994 ◽

Vol 31 (2) ◽

pp. 160-164 ◽

Cited By ~ 5

Author(s):

Thorkild Friis ◽

Laurids R Pedersen ◽

Susanne Arnold-Larsen ◽

Dorthe B Nielsen

Keyword(s):

Blood Pressure ◽

Cross Sectional Study ◽

Diabetic Patients ◽

Sectional Study ◽

Sex Distribution ◽

Type 2 Diabetic Patients ◽

Cross Sectional ◽

C Peptide ◽

Type 2 Diabetic

We studied 112 type 2 diabetic patients. Fourteen patients had frank proteinuria, and 37 of the remaining 98 had microalbuminuria which was more frequent in men than in women ( P<0·02). Hypertension was found in 47 of the patients, equally distributed between sexes. Male diabetics with microalbuminuria had higher systolic blood pressure than diabetics without microalbuminuria ( P<0·02). Body mass index was higher in both sexes with hypertension compared to patients without hypertension. In the hypertensive men plasma C-peptide values were higher compared to patients without hypertension ( P<0·01) irrespective of the presence of microalbuminuria. A positive correlation between blood pressure and C-peptide was found ( P<0·01) in the men. We suggest that gender should be taken into account in the analysis and interpretation of microalbuminuria in type 2 diabetes.

Download Full-text