Analyzing the relationship between traditional Chinese medicine patterns and biochemical parameters in CKD population based on informations sharing system

2013 ◽  
Author(s):  
Yi-fan Wu ◽  
La Zhang ◽  
Yu-ping Zeng ◽  
Xu-sheng Liu ◽  
Hao-yang Fu
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Biochemical Parameters ◽  
Population Based ◽  
The Relationship

Use of traditional Chinese medicine in patients with hyperlipidemia: A population-based study in Taiwan

2015 ◽  
Vol 168 ◽  
pp. 129-135 ◽  
Author(s):  
Shih-Meng Chu ◽  
Wei-Tai Shih ◽  
Yao-Hsu Yang ◽  
Pau-Chung Chen ◽  
Yen-Hua Chu
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Population Based ◽  
Population Based Study

The impact of Traditional Chinese Medicine on mitophagy in disease models

2021 ◽  
Vol 27 ◽  
Author(s):  
Li-Ping Yu ◽  
Ting-Ting Shi ◽  
Yan-Qin Li ◽  
Jian-Kang Mu ◽  
Ya-Qin Yang ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Molecular Mechanisms ◽  
Human Diseases ◽  
Regulatory Mechanisms ◽  
Disease Models ◽  
Relationship Of ◽  
The Impact ◽  
The Relationship

: Mitophagy plays an important role in maintaining mitochondrial quality and cell homeostasis through the degradation of damaged, aged, and dysfunctional mitochondria and misfolded proteins. Many human diseases, particularly neurodegenerative diseases, are related to disorders of mitochondrial phagocytosis. Exploring the regulatory mechanisms of mitophagy is of great significance for revealing the molecular mechanisms underlying the related diseases. Herein, we summarize the major mechanisms of mitophagy, the relationship of mitophagy with human diseases, and the role of traditional Chinese medicine (TCM) in mitophagy. These discussions enhance our knowledge of mitophagy and its potential therapeutic targets using TCM.

scholarly journals Traditional Chinese Medicine Decreases the Stroke Risk of Systemic Corticosteroid Treatment in Dermatitis: A Nationwide Population-Based Study

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Kao-Sung Tsai ◽  
Chia-Sung Yen ◽  
Po-Yuan Wu ◽  
Jen-Huai Chiang ◽  
Jui-Lung Shen ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Stroke Risk ◽  
Systemic Corticosteroid ◽  
Strong Association ◽  
Corticosteroid Treatment ◽  
Epidemiological Studies ◽  
Population Based ◽  
Rank Test ◽  
Increased Risk

Epidemiological studies have shown a strong association between dermatitis and stroke. Systemic corticosteroid, the mainstay treatment for dermatitis, could enhance the atherosclerotic process. Traditional Chinese Medicine (TCM) has been used for dermatitis to decrease the side effects of corticosteroid. However, the different stroke risk in dermatitis patients treated with systemic corticosteroid or TCM remains unclear. This study identified 235,220 dermatitis patients and same comorbidity matched subjects between 2000 and 2009 from database of NHRI in Taiwan. The two cohorts were followed until December 31, 2011. The primary outcome of interest was new diagnosis of stroke. The crude hazard ratio (HR) for future stroke among dermatitis patients treated with systemic corticosteroid was 1.40 (95% CI, 1.34–1.45;P<0.0001) and TCM was 1.09 (95% CI, 1.05–1.13;P<0.0001). The log-rank test showed a higher cumulative incidence of ischemic stroke in the patient treated with only systemic corticosteroid group than that treated with systemic corticosteroid and TCM, only TCM, and neither systemic corticosteroid nor TCM in the matched cohort during the follow-up period (P<0.0001). We demonstrated that patients treated with systemic corticosteroid had an increased risk of stroke and that the risk probably decreased by TCM treatment.

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