scholarly journals Antibody injection in the egg yolk: maternal antibodies affect humoral immune response of the offspring

2010 ◽  
Vol 24 (6) ◽  
pp. 1333-1341 ◽  
Author(s):  
Vincent Staszewski ◽  
Heli Siitari
Keyword(s):  
Immune Response ◽  
Humoral Immune Response ◽  
Egg Yolk ◽  
Maternal Antibodies ◽  
Humoral Immune

Modulating effect of a new ester, 28-O-phosphatidylbetulin (DAPB), obtained from hen egg yolk lecithin and betulin on lymphocyte subsets and humoral immune response in mice

2019 ◽  
Vol 41 (2) ◽  
pp. 231-241
Author(s):  
Magdalena Lis ◽  
Barbara Barycza ◽  
Angelika Sysak ◽  
Aleksandra Pawlak ◽  
Agnieszka Suszko-Pawłowska ◽  
...  
Keyword(s):  
Immune Response ◽  
Humoral Immune Response ◽  
Lymphocyte Subsets ◽  
Egg Yolk ◽  
Humoral Immune ◽  
Hen Egg Yolk ◽  
Hen Egg

scholarly journals Humoral immunity in puppies of immune bitches vaccinated with an attenuated and inactivated

2002 ◽  
Vol 56 (5-6) ◽  
pp. 285-294 ◽  
Author(s):  
Dragan Bacic ◽  
Sonja Obrenovic ◽  
Miroslav Valcic ◽  
Dragisa Trailovic ◽  
Djordje Dobric
Keyword(s):  
Immune Response ◽  
Humoral Immunity ◽  
Humoral Immune Response ◽  
Maternal Antibodies ◽  
Inactivated Vaccine ◽  
Specific Antibodies ◽  
Humoral Immune ◽  
Attenuated Vaccine ◽  
Expected Increase

In order to examine the humoral immune response to a vaccine against canine parvoviruses in puppies of immune bitches, vaccinated during gravidity, an experiment was performed on a total of 56 puppies from 10 litters, which were vaccinated three times, on the 7th, 11th, and 17th weeks of life. One group of puppies was vaccinated with an attenuated vaccine, while another was vaccinated with an inactivated vaccine. The titer of maternal antibodies and the vaccine - induced titer of specific antibodies were examined using the IHA test. The titer of maternal antibodies in puppies before the first vaccination ranged from <20 to 1:80. Following vaccination, we established an expected increase in the titer of specific antibodies, over 1:160 without more significant differences between the two types of vaccines.

Role of Yersinia pseudotuberculosis outer proteins (Yops) in murine humoral immune response

2009 ◽  
Vol 54 (3) ◽  
pp. 239-245 ◽  
Author(s):  
J. M. L. Maia ◽  
L. G. S. Monnazzi ◽  
B. M. M. Medeiros
Keyword(s):  
Immune Response ◽  
Humoral Immune Response ◽  
Yersinia Pseudotuberculosis ◽  
Humoral Immune

scholarly journals Diagnostic and analytical performance evaluation of ten commercial assays for detecting SARS-CoV-2 humoral immune response

2021 ◽  
pp. 113043
Author(s):  
Marnix Mylemans ◽  
Eveline Van Honacker ◽  
Louis Nevejan ◽  
Stefanie van den Bremt ◽  
Laura Hofman ◽  
...  
Keyword(s):  
Immune Response ◽  
Performance Evaluation ◽  
Humoral Immune Response ◽  
Analytical Performance ◽  
Humoral Immune

scholarly journals SARS-CoV-2 RNA and antibodies in tear fluid

2021 ◽  
Vol 6 (1) ◽  
pp. e000733
Author(s):  
Astrid Muyldermans ◽  
Maria Bjerke ◽  
Thomas Demuyser ◽  
Deborah De Geyter ◽  
Ingrid Wybo ◽  
...  
Keyword(s):  
Immune Response ◽  
Humoral Immune Response ◽  
Spike Protein ◽  
Tear Fluid ◽  
Local Response ◽  
Schirmer Test ◽  
Humoral Immune ◽  
Non Invasive ◽  
Reverse Transcription Pcr ◽  
Ocular Symptoms

Background/aimsSARS-CoV-2 is highly contagious. More evidence concerning extrapulmonary transmission routes such as the eyes is urgently needed. Although the humoral immune response is important in the viral containment, the local response in tears has not yet been studied. The aim of our study was twofold: to assess the prevalence of both SARS-CoV-2 RNA and antibodies in tear fluid.MethodsIn a first series, nasopharyngeal sampling and tear sampling by Schirmer test strips were performed in 26 acutely ill patients with COVID-19 to assess the presence of SARS-CoV-2 RNA by reverse transcription PCR. In a second series, IgG and IgA responses to SARS-CoV-2 spike protein in serum and tear fluid of convalescent individuals (n=22) were compared with control individuals (n=15) by ELISA.ResultsSARS-CoV-2 RNA was detected in tears of 7/26 (26.9%) patients with COVID-19. None of them had ocular symptoms. Convalescent individuals displayed a significant higher ratio of IgG (p<0.0001) and IgA (p=0.0068) in tears compared with control individuals. A sensitivity of 77.3% and specificity of 93.3% was observed for IgG, and 59.1% and 100% for IgA.ConclusionsOur results demonstrate the presence of SARS-CoV-2 RNA and a local IgG and IgA immune response in tear fluid. These data confirm the possibility of SARS-CoV-2 transmission through tear fluid and the importance of the eye as a first defence against SARS-CoV-2, indicating the potential of tears as a non-invasive surrogate for serum in monitoring the host immune response.

scholarly journals Maternally Derived Antibody Levels Influence on Vaccine Protection against PCV2d Challenge

Animals ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 2231
Author(s):  
István Kiss ◽  
Krisztina Szigeti ◽  
Zalán G. Homonnay ◽  
Vivien Tamás ◽  
Han Smits ◽  
...  
Keyword(s):  
Immune Response ◽  
Humoral Immune Response ◽  
Subunit Vaccine ◽  
Porcine Circovirus Type ◽  
Porcine Circovirus ◽  
Vaccine Protection ◽  
Humoral Immune ◽  
Negative Effect ◽  
Antibody Levels

Piglets from a porcine circovirus type 2 (PCV2) stable farm of low and high levels of maternally derived antibodies (MDA) against PCV2 were vaccinated either with a whole virus type or a PCV2 ORF2 antigen-based commercial subunit vaccine at three weeks of age. Two non-vaccinated groups served as low and high MDA positive controls. At four weeks post vaccination, all piglets were challenged with a PCV2d-2 type virus strain and were checked for parameters related to vaccine protection over a four-week observation period. MDA levels evidently impacted the outcome of the PCV2d-2 challenge in non-vaccinated animals, while it did not have a significant effect on vaccine-induced protection levels. The humoral immune response developed faster in the whole virus vaccinates than in the subunit vaccinated pigs in the low MDA groups. Further, high MDA levels elicited a stronger negative effect on the vaccine-induced humoral immune response for the subunit vaccine than for the whole virus vaccine. The group-based oral fluid samples and the group mean viraemia and faecal shedding data correlated well, enabling this simple, and animal welfare-friendly sampling method for the evaluation of the PCV2 viral load status of these nursery piglets.

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