Intravascular papillary endothelial hyperplasia of the lower lip: surgical approach and review of the literature

Gerodontology ◽  
2009 ◽  
Vol 26 (4) ◽  
pp. 305-308 ◽  
Author(s):  
A. Cohen ◽  
A. Maly ◽  
B. Azaz
2009 ◽  
Vol 2009 ◽  
pp. 1-5 ◽  
Author(s):  
Hisanobu Yonezawa ◽  
Akimitsu Hiraki ◽  
Ken-ichi Iyama ◽  
Masanori Shinohara

Intravascular papillary endothelial hyperplasia is a benign nonneoplastic vascular lesion that consists of endothelial cells with abundant vascular tissue with papillary proliferation. An adult female had a painless growing dark red nodule on the left side of the lower lip and often touched and gnawed at it for more than 4 years. The lesion was a tender, smooth mass approximately 1 cm in diameter without discoloration reaction. Magnetic resonance imaging of the lesion showed specific findings. She was diagnosed clinically as having mimicked hemangioma, and the lesion was totally excised under local anesthesia. Histopathological examination revealed that papillary proliferated endothelial cells with venous pool, and the lesion was diagnosed as intravascular papillary endothelial hyperplasia associated with venous pool. There has been no recurrence for more than 1 year. Despite the benign nature of this lesion, it could have been mistaken for a malignant tumor because of its clinical course and radiologic findings.


1997 ◽  
Vol 86 (3) ◽  
pp. 558-563 ◽  
Author(s):  
Rudolf A. Kristof ◽  
Dirk Van Roost ◽  
Helmut K. Wolf ◽  
Johannes Schramm

✓ Intravascular papillary endothelial hyperplasia (IPEH) is considered a reactive proliferation of endothelium associated with thrombosis. The occurrence of IPEH in the cranial cavity is exceedingly rare. In this article, the authors report three cases of IPEH that originated from the cavernous sinus and extended into the sellar contents. The lesions were resected incompletely in two cases and completely in one case. The IPEH in one of the patients was incompletely resected and exhibited further growth on magnetic resonance imaging 3 months postoperatively; local radiation therapy was instituted. This led to shrinkage of the lesion over an additional follow-up period of 3.5 years. In a review of the literature, the authors located seven other cases of intracranial IPEH. The authors conclude that clinically symptomatic intracranial IPEH should be completely resected whenever possible, because it can cause considerable morbidity and mortality and because it is prone to progression or recurrence.


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