Morphological peculiarities of the papillary muscles of the human heart ventricles in the norm applying of the laser polarimetry method

2020 ◽  
Author(s):  
Sergey B. Yermolenko ◽  
Natalia P. Penteleichuk ◽  
Yulia Y. Malyk ◽  
Tatjana O. Semeniuk ◽  
Tatjana V. Protsak ◽  
...  
Keyword(s):  
Human Heart ◽  
Papillary Muscles ◽  
Laser Polarimetry ◽  
Heart Ventricles

scholarly journals The absence of dystrophin brain isoform expression in healthy human heart ventricles explains the pathogenesis of 5' X-linked dilated cardiomyopathy

2012 ◽  
Vol 13 (1) ◽  
Author(s):  
Marcella Neri ◽  
Emanuele Valli ◽  
Giovanna Alfano ◽  
Matteo Bovolenta ◽  
Pietro Spitali ◽  
...  
Keyword(s):  
Dilated Cardiomyopathy ◽  
Human Heart ◽  
Healthy Human ◽  
Heart Ventricles ◽  
Isoform Expression

Myocardial fiber architecture of the human heart ventricles

1982 ◽  
Vol 204 (2) ◽  
pp. 137-147 ◽  
Author(s):  
M. A. Fernandez-Teran ◽  
J. M. Hurle
Keyword(s):  
Human Heart ◽  
Fiber Architecture ◽  
Myocardial Fiber ◽  
Heart Ventricles

The peroxisome proliferator-activated receptor gamma (PPARγ) is highly expressed in human heart ventricles

2002 ◽  
Vol 56 (8) ◽  
pp. 407-410 ◽  
Author(s):  
Mohammad R. Mehrabi ◽  
Theresia Thalhammer ◽  
Petra Haslmayer ◽  
Helmut D. Glogar ◽  
Georg Wieselthaler ◽  
...  
Keyword(s):  
Human Heart ◽  
Peroxisome Proliferator ◽  
Peroxisome Proliferator Activated Receptor ◽  
Heart Ventricles

scholarly journals Increased Angiotensin-(1-7)–Forming Activity in Failing Human Heart Ventricles

Circulation ◽  
2003 ◽  
Vol 108 (14) ◽  
pp. 1707-1712 ◽  
Author(s):  
Lawrence S. Zisman ◽  
Rebecca S. Keller ◽  
Barbara Weaver ◽  
Qishan Lin ◽  
Robert Speth ◽  
...  
Keyword(s):  
Human Heart ◽  
Heart Ventricles

scholarly journals Comparison of Biomechanical Properties and Microstructure of Trabeculae Carneae, Papillary Muscles, and Myocardium in the Human Heart

2018 ◽  
Vol 141 (2) ◽  
Author(s):  
Fatemeh Fatemifar ◽  
Marc D. Feldman ◽  
Meagan Oglesby ◽  
Hai-Chao Han
Keyword(s):  
Human Heart ◽  
Computational Models ◽  
Strain Energy Function ◽  
Tensile Tests ◽  
Left Ventricular ◽  
Collagen Content ◽  
Uniaxial Tensile ◽  
Papillary Muscles ◽  
Microstructural Characteristics ◽  
Ventricular Compliance

Trabeculae carneae account for a significant portion of human ventricular mass, despite being considered embryologic remnants. Recent studies have found trabeculae hypertrophy and fibrosis in hypertrophied left ventricles with various pathological conditions. The objective of this study was to investigate the passive mechanical properties and microstructural characteristics of trabeculae carneae and papillary muscles compared to the myocardium in human hearts. Uniaxial tensile tests were performed on samples of trabeculae carneae and myocardium strips, while biaxial tensile tests were performed on samples of papillary muscles and myocardium sheets. The experimental data were fitted with a Fung-type strain energy function and material coefficients were determined. The secant moduli at given diastolic stress and strain levels were determined and compared among the tissues. Following the mechanical testing, histology examinations were performed to investigate the microstructural characteristics of the tissues. Our results demonstrated that the trabeculae carneae were significantly stiffer (Secant modulus SM2 = 80.06 ± 10.04 KPa) and had higher collagen content (16.10 ± 3.80%) than the myocardium (SM2 = 55.14 ± 20.49 KPa, collagen content = 10.06 ± 4.15%) in the left ventricle. The results of this study improve our understanding of the contribution of trabeculae carneae to left ventricular compliance and will be useful for building accurate computational models of the human heart.

scholarly journals Microscopic and ultramicroscopic structure of typical chordae tendineae of the human’s left ventricle bicuspid valve

2021 ◽  
Vol 25 (1(97)) ◽  
pp. 68-74
Author(s):  
Yu. Malyk ◽  
T. Semeniuk ◽  
N. Penteleichuk
Keyword(s):  
Mitral Valve ◽  
Connective Tissue ◽  
Elastic Layer ◽  
Human Heart ◽  
Histological Structure ◽  
Papillary Muscles ◽  
Fibrous Connective Tissue ◽  
Chordae Tendineae ◽  
Submicroscopic Structure ◽  
The Core

Objective – to determine the features of the micro- and submicroscopic structure of typical chordae tendineae of the mitral valve of the human heart.Materials and methods. This study was made on preparations of 35 human hearts, in particular the chordae tendineae of the bicuspid valves of the left ventricles of children and people of early and middle adulthood using the methods of light and electron microscopy.Results. The study of typical chordae tendineae of the mitral valve leaflets was made using the microscopic method and the method of electron microscopy. The areas where the chordae tendineae diverge from the papillary muscles, the middle third of the chordae tendineae, and the place of attachment of the chordae tendineae to the mitral valve leaflets were studied. Chordae tendineae are covered with endothelium from all sides. A peripheral collagen-elastic layer of loose fibrous connective tissue is localized under the endothelium, along the entire perimeter of the chordae tendineae and it differs in structure in different parts of the chordae at the submicroscopic level. Bundles of densely packed collagen fibers, which are oriented rectilinearly along the chordae, form the core of the chordae tendineae. Bundles of striated cardiac typical muscle cells are localized in areas where the chordae tendineae origin from the papillary muscles. It was found that in the composition of the chordae tendineae of children the cellular component in the fibrous connective tissue predominates during comparing the typical chordae tendineae of different aged people.Conclusions. This morphological study made it possible to obtain new information and to clarify the data that are already known to morphologists on the micro- and submicroscopic structure of typical chordae tendineae of the mitral valve of the human heart. We found that differences in the histological structure are more typical for the areas of origin of typical chordae tendineae from the papillary muscles and areas of their attachment to the leaflets of the mitral valve. The diameter of the core of the chordae tendineae increases and the thickness of the loose peripheral collagen-elastic layer decreases with age. The received data can serve as a theoretical basis for the further comparative morphological and clinical studies of the mitral valve of the human heart. That, in turn, will facilitate to an increasing the level of diagnostic, to improve methods of prevention and treatment of minor heart anomalies, congenital and acquired defects of the valvular apparatus of the heart.

scholarly journals Morphometric study on papillary muscles of human tricuspid valve-dissection method

2021 ◽  
Vol 8 (3) ◽  
pp. 190-193
Author(s):  
Chandragirish S ◽  
Harsha B R ◽  
Girish V Patil
Keyword(s):  
Tricuspid Valve ◽  
Human Heart ◽  
Morphometric Study ◽  
Papillary Muscles ◽  
Mean Width ◽  
Length Width ◽  
Valve Diseases ◽  
Standard Techniques ◽  
Modern Technologies ◽  
Formalin Fixed

Aim of the present study was to observe the measurements of anterior papillary muscles present in tricuspid valve of human heart. Measurements of anterior papillary muscles in tricuspid valve gains utmost importance in cardiac surgeries because they are the causes of myocardial infarction in recent times because of its variations and detection of these causes by advent in modern technologies which will help in treatment of tricuspid valve diseases. This study was carried out on 96 normal formalin fixed human heart specimens. Dissection was performed according to standard techniques. Anterior papillary muscles were observed and length, width and thickness of each muscle were measured and documented. In the present study, numbers of anterior papillary muscles were present with a frequency of 1-3, with most common appearance of 1 muscle in 66 hearts (68.8%) and least common incidence of 3 muscles in 6 hearts (6.3%). Anterior papillary muscles were present in all 96 hearts. In measurements, anterior papillary muscles mean height was 1.49±0.44 cm; mean width was 0.82±0.21 cm and mean thickness was 0.64±0.15 cm respectively. We hope this study will serve to understand the morphometry of anterior papillary muscles better and will help in various surgical procedures and cardiac treatment done on tricuspid valve.

Anatomical basis for the separation of four cardiac zones in the walls of human heart ventricles

1994 ◽  
Vol 16 (4) ◽  
pp. 355-361 ◽  
Author(s):  
NR Grande ◽  
D Taveira ◽  
AC e Silva ◽  
AS Pereira ◽  
AP Águas
Keyword(s):  
Human Heart ◽  
Heart Ventricles ◽  
Anatomical Basis
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