PHOTODYNAMIC THERAPY — AN UPDATE ON CLINICAL APPLICATIONS

2009 ◽  
Vol 02 (01) ◽  
pp. 73-92 ◽  
Author(s):  
ZHENG HUANG ◽  
LIBO LI ◽  
HONGWEI WANG ◽  
XIULI WANG ◽  
KAIHUA YUAN ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Clinical Application ◽  
Clinical Data ◽  
Basic Research ◽  
Clinical Applications ◽  
Review Article ◽  
Malignant Diseases ◽  
New Development ◽  
The World ◽  
Future Direction

Photodynamic therapy (PDT) has received increased attention since the regulatory approvals of several photosensitizers and light applicators in numerous countries and regions around the world. In recent years, much progress has been seen in basic research as well as clinical application. PDT clinical application has now extended from treating malignant diseases to nonmalignant diseases. This review article will present recent clinical data published in English journals. The data will be organized according to their clinical specialties. The new development and future direction in clinical applications of PDT for the management of both malignant and nonmalignant diseases will be discussed.

scholarly journals Introduction to the Medicines Special Issue on Acupuncture—Basic Research and Clinical Application

Medicines ◽  
2018 ◽  
Vol 5 (3) ◽  
pp. 99
Author(s):  
Gerhard Litscher
Keyword(s):  
Clinical Application ◽  
Basic Research ◽  
Clinical Applications ◽  
Evidence Based ◽  
Special Issue ◽  
The World ◽  
Acupuncture Research

This Medicines special issue focuses on the further investigation, development, and modernization of acupuncture in basic research settings, as well as in clinical applications. The special issue contains 12 articles reporting latest evidence-based results of acupuncture research, and exploring acupuncture in general. Altogether 44 authors from all over the world contributed to this special issue.

scholarly journals Pancreatic Cancers: A Review of Studies from Pakistan and Comparison with Global Trends

2021 ◽  
Vol 11 (2) ◽  
pp. 120-127
Author(s):  
Saleema Mehboob Ali ◽  
Yumna Adnan ◽  
S. M. Adnan Ali
Keyword(s):  
Pancreatic Cancer ◽  
Clinical Data ◽  
Association Studies ◽  
Epidemiological Data ◽  
Review Article ◽  
Diagnostic Tools ◽  
Global Trends ◽  
Pancreatic Cancers ◽  
The World ◽  
Prediction Of Prognosis

The objective of this review article is to discuss clinical data from studies on Pakistani pancreatic cancer population and its comparison with international data. This review article will allow researchers to identify gaps in the data and hence to design further research in order to address these gaps accordingly. Search was carried out via Google Scholar, PubMed and PakMediNet search engines using keywords “Pancreatic cancers”, “Pancreatic adenocarcinoma” and “Pakistan”. Pancreatic cancers are one of the most lethal cancers globally. Statistics show that 97.8% of cases of pancreatic cancers in Pakistan have led to mortality. For various cancers around the world, epidemiological data has been used for development of diagnostic tools and therapies. Despite the alarming situation of pancreatic cancers in Pakistan, only limited work has been done in this area. Majority of the studies are based exclusively on reporting of clinical data. Pakistan has not been able to even gather sufficient data to proceed research based on association of molecular aspects of tumor with clinical characteristics. On the contrary, researchers, scientists and clinicians from other parts of the world are already working on association studies, prediction of prognosis, treatment selection and improving the survival of their population. It is an immense need of the situation that molecular based studies are carried out on Pakistani pancreatic cancer population so that diagnosis, prognosis, treatment and survival of these patients can be made better.

scholarly journals Current Status and Future Prospects of Proton MR Spectroscopy of the Breast with a 1.5T MR Unit

2010 ◽  
Vol 2010 ◽  
pp. 1-10 ◽  
Author(s):  
Mitsuhiro Tozaki ◽  
Katsuya Maruyama
Keyword(s):  
Mammary Gland ◽  
Clinical Practice ◽  
Clinical Data ◽  
Mr Spectroscopy ◽  
Basic Research ◽  
Clinical Applications ◽  
Current Status ◽  
Future Prospects ◽  
Proton Mr Spectroscopy ◽  
Malignant Lesions

Proton MR spectroscopy of the mammary gland area is used to be considered in the realm of basic research, but as a result of the advances in MR techniques, it is now being performed in ordinary clinical practice. It is particularly noteworthy that useful clinical data are now being accumulated with 1.5T MR units, which are the standard units. We think that, at this point, it is very important to systematically review the techniques, clinical applications, and future prospects of proton MR spectroscopy. We have performed proton MR spectroscopy with a 1.5T MR unit in over 3000 cases at our hospital. In this paper, we will comment on the current status of proton MR spectroscopy of the breast, primarily in regard to differentiation between benign and malignant lesions and prediction of the efficacy of chemotherapy while describing the data obtained at our hospital.

scholarly journals PROSPECT OF USING PROPOLIS IN CONSERVATIVE DENTISTRY AND ENDODONTIC TREATMENT (BASIC RESEARCH VS CLINICAL APPLICATION)

2014 ◽  
Vol 18 (2) ◽  
pp. 185-189
Author(s):  
Ardo Sabir
Keyword(s):  
Clinical Application ◽  
Basic Research ◽  
Review Article ◽  
Chemical Diversity ◽  
Tissue Properties ◽  
Rich Variety ◽  
Storage Media ◽  
Conservative Dentistry ◽  
The Subject

Propolis is a resinous hive product, collected by bees from tree buds and mixed with secreted bee wax in order to avoidbacterial contamination in the hive, and also to seal it. It is acknowledged that propolis has antimicrobial activity as wellas anti-inflammatory, antioxidant, antitumor, immuno-regulatory, and regenerative tissue properties. Chemically, propolisis exceedingly complex and contains a rich variety of potent terpene, benzoic, caffeic, cinnamic, aromatic aldehyde,phenolic acid, and also high in flavonoid. Recently, propolis has been the subject of several studies, both in vitro and invivo or even at animal or human with the aim to elucidate its biological and pharmacological properties. The use ofpropolis in dentistry has been done in few years ago for various purposes such as in treatment of periodontitis and dentalcaries, to accelerate the healing of post-extraction wounds, to treat aphthous stomatitis, as a storage media following teethavulsion. The result of basic research of propolis apparently was useful to support its clinical application in dentistry.However, standardization the composition of propolis due to its chemical diversity is still a problem. Therefore thepurposes of this review article were (1) to explain the prospect of propolis in conservative dentistry and endodontictreatment, and (2) to stimulate the interest of clinicians to make further research about this natural compound in dentistry.In conclusion, propolis is a natural medication with a promising future but further studies should be conducted toinvestigate its merit and demerits in clinical dentistry

Radioimmunodetection of Malignant Melanoma with the 225.28S Monoclonal Antibody to HMW-MAA

1986 ◽  
Vol 25 (06) ◽  
pp. 220-224 ◽  
Author(s):  
G. L. Buraggi
Keyword(s):  
Monoclonal Antibody ◽  
Pilot Study ◽  
Malignant Melanoma ◽  
Prospective Study ◽  
Clinical Application ◽  
Multicenter Trial ◽  
Clinical Applications ◽  
Gamma Energy ◽  
A Prospective Study ◽  
Antigen Antibody

A review of the studies on the use of the antigen-antibody system HMW-MAA 225.28S in melanoma radioimmunodetection is reported. The results obtained in a pilot study (42 patients with 74 lesions), a multicenter trial (254 patients with 553 lesions) and a prospective study still outstanding (29 patients with 38 lesions) allow to consider this system as suitable for clinical application. F(ab′)2 labelled with 99mTc gave the best results in terms of positivity. Moreover this radioisotope allows the best dosimetric conditions. The gamma energy emitted by this radionuclide is particularly convenient for conventional scintillation cameras and ECT. Very good results in terms of sensitivity (70%-85%) and especially specificity (about 100%) were achieved. Possible clinical applications of the method are discussed.

THE EFFECT OF SELF CONFIDENCE, QUALITY EDUCATION AND FAMILY ENVIRONMENT ON INDONESIAN YOUTH IN ENTREPRENEURSHIP

2018 ◽  
Vol 1 (1) ◽  
pp. 29-40
Author(s):  
Novita Novita ◽  
Damar Aji Irawan ◽  
Benyamin Suwitorahardjo
Keyword(s):  
Family Environment ◽  
Research Method ◽  
Basic Research ◽  
Quality Education ◽  
Self Confidence ◽  
Job Opportunities ◽  
The World ◽  
The Future

The biggest challenge faced by students nowadays and in the future, is how to deal with the increasingly high competition in the world, the increasing number of undergraduate and limited job opportunities. In this kind of situations, the students had to find a creative way and change the approach of being a university graduate looking for a job, to become scholars who can create their own jobs, or even able to create jobs for others. The purpose of this study was to determine the youth interest on entrepreneurship in Indonesia. It seems that the youth are unaware to see that the job is increasingly difficult to find nowadays. So through this study, researchers wanted to find out what causes youth in Indonesia, reluctant to become an entrepreneur. While being an entrepreneur, the youth can open or create jobs for others and can reduce the level of unemployment in Indonesia. Self-confidence is an important factor in entrepreneurship. Family environment and quality education also participate in creating interest for youth in entrepreneurship. This research is using basic research method; where researchers will try to link the theories of the existing variables. Thus, researchers can conduct research by distributing questionnaires to the youth throughout Indonesia. This study aims to determine the cause of Indonesian youth lack of interest in entrepreneurship.

Critical Insight into the Attributes of Emerging Novel Coronavirus (COVID-19) in India and Across the World

Coronaviruses ◽  
2020 ◽  
Vol 1 (1) ◽  
pp. 49-56
Author(s):  
Gaurav M. Doshi ◽  
Hemen S. Ved ◽  
Ami P. Thakkar
Keyword(s):  
Review Article ◽  
World Health ◽  
Effective Vaccine ◽  
Human Contact ◽  
The World ◽  
Critical Insight ◽  
Novel Coronavirus ◽  
Health Organization ◽  
Insight Into ◽  
Old Drugs

The World Health Organization (WHO) has recently announced the spread of novel coronavirus (nCoV) globally and has declared it a pandemic. The probable source of transmission of the virus, which is from animal to human and human to human contact, has been established. As per the statistics reported by the WHO on 11th April 2020, data has shown that more than sixteen lakh confirmed cases have been identified globally. The reported cases related to nCoV in India have been rising substantially. The review article discusses the characteristics of nCoV in detail with the probability of potentially effective old drugs that may inhibit the virus. The research may further emphasize and draw the attention of the world towards the development of an effective vaccine as well as alternative therapies. Moreover, the article will help to bridge the gap between the new researchers since it’s the current thrust area of research.

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