Abstract 5668: The rational design and evaluation of a peptide inhibitor of the PD-1/PD-L1 interaction

2018 ◽  
Author(s):  
Rebecca J. Boohaker ◽  
Vijaya Sambandam ◽  
Mark Suto ◽  
Bo Xu
Keyword(s):  
Rational Design ◽  
Peptide Inhibitor

Rational design and development of a peptide inhibitor for the PD-1/PD-L1 interaction

2018 ◽  
Vol 434 ◽  
pp. 11-21 ◽  
Author(s):  
Rebecca J. Boohaker ◽  
Vijaya Sambandam ◽  
Isaac Segura ◽  
James Miller ◽  
Mark Suto ◽  
...  
Keyword(s):  
Rational Design ◽  
Peptide Inhibitor ◽  
Design And Development

scholarly journals The Rational Design of Specific Peptide Inhibitor against p38α MAPK at Allosteric-Site: A Therapeutic Modality for HNSCC

PLoS ONE ◽  
2014 ◽  
Vol 9 (7) ◽  
pp. e101525 ◽  
Author(s):  
Kamaldeep Gill ◽  
Lokesh Nigam ◽  
Ratnakar Singh ◽  
Suresh Kumar ◽  
Naidu Subbarao ◽  
...  
Keyword(s):  
Rational Design ◽  
Therapeutic Modality ◽  
Peptide Inhibitor ◽  
Allosteric Site ◽  
P38α Mapk ◽  
Specific Peptide

Rational Design of a Highly Potent and Selective Peptide Inhibitor of PACE4 by Salt Bridge Interaction with D160 at Position P3

ChemMedChem ◽  
2017 ◽  
Vol 12 (15) ◽  
pp. 1169-1172 ◽  
Author(s):  
Vahid Dianati ◽  
Azar Shamloo ◽  
Anna Kwiatkowska ◽  
Roxane Desjardins ◽  
Armand Soldera ◽  
...  
Keyword(s):  
Rational Design ◽  
Salt Bridge ◽  
Peptide Inhibitor

scholarly journals Rational design of a potent macrocyclic peptide inhibitor targeting the PD-1/PD-L1 protein–protein interaction

RSC Advances ◽  
2021 ◽  
Vol 11 (38) ◽  
pp. 23270-23279
Author(s):  
Qi Miao ◽  
Wanheng Zhang ◽  
Kuojun Zhang ◽  
He Li ◽  
Jidong Zhu ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Protein Interaction ◽  
Rational Design ◽  
Peptide Inhibitor ◽  
Protein Protein Interaction ◽  
Comparable Activity ◽  
L1 Protein ◽  
Macrocyclic Peptide

The co-crystal structure and CADD-guided rational design of JMPDP-027 which has comparable activity to mAb in both in vitro and in vivo tests.

Molecular insights on the dynamic stability of peptide nucleic acid functionalized carbon and boron nitride nanotubes

2021 ◽  
Vol 23 (1) ◽  
pp. 219-228
Author(s):  
Nabanita Saikia ◽  
Mohamed Taha ◽  
Ravindra Pandey
Keyword(s):  
Nucleic Acid ◽  
Boron Nitride ◽  
Nucleic Acids ◽  
Dynamic Stability ◽  
Peptide Nucleic Acid ◽  
Rational Design ◽  
Peptide Nucleic Acids ◽  
Boron Nitride Nanotubes ◽  
Molecular Hybrids ◽  
Single Wall Nanotubes

The rational design of self-assembled nanobio-molecular hybrids of peptide nucleic acids with single-wall nanotubes rely on understanding how biomolecules recognize and mediate intermolecular interactions with the nanomaterial's surface.

Optimizing electron density of nickel sulfide electrocatalysts through sulfur vacancy engineering for alkaline hydrogen evolution

2020 ◽  
Vol 8 (35) ◽  
pp. 18207-18214
Author(s):  
Dongbo Jia ◽  
Lili Han ◽  
Ying Li ◽  
Wenjun He ◽  
Caichi Liu ◽  
...  
Keyword(s):  
Hydrogen Evolution ◽  
Electron Density ◽  
Rational Design ◽  
Nickel Sulfide ◽  
Catalytic Performance ◽  
Sulfide Catalysts ◽  
Sulfur Vacancy

A novel, rational design for porous S-vacancy nickel sulfide catalysts with remarkable catalytic performance for alkaline HER.

Sign in / Sign up

Export Citation Format

Share Document