Inflammatory myofibroblastic tumour of the conjunctiva masquerading as ocular surface squamous neoplasia

2020 ◽  
pp. 112067212097361
Author(s):  
Manpreet Singh ◽  
Manu Saini ◽  
Debajyoti Chatterjee ◽  
Aditi Mehta ◽  
Manpreet Kaur ◽  
...  
Keyword(s):  
Amniotic Membrane ◽  
Ocular Surface ◽  
Surgical Excision ◽  
Excision Biopsy ◽  
Inflammatory Myofibroblastic Tumour ◽  
Complete Surgical Excision ◽  
Oral Steroids ◽  
Rare Site ◽  
The Right

A 63-year-male had painless, progressive, yellowish-pink, immobile conjunctival mass with prominent feeder vessels in the right eye of 1-year duration. The rest of the ophthalmic examination was unremarkable. MRI showed no extension into orbit or extraocular muscles. An excision biopsy with the amniotic membrane patch was performed. Histopathology confirmed inflammatory myofibroblastic tumour (IMT) with SMA and calponin positivity on immunohistochemistry. Complete surgical excision, amniotic membrane, and oral steroids provided long-term relief from recurrence. The conjunctiva is a rare site for IMT, and IMT should be kept in the differentials for atypical cases of ocular surface neoplasia.

scholarly journals Primary Neuroendocrine Carcinoma of Ocular Adnexa

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Daisuke Yamanouchi ◽  
Toshiyuki Oshitari ◽  
Yosuke Nakamura ◽  
Jiro Yotsukura ◽  
Kaoru Asanagi ◽  
...  
Keyword(s):  
Neuroendocrine Carcinoma ◽  
Lacrimal Gland ◽  
Histopathological Examination ◽  
Combined Therapy ◽  
Surgical Excision ◽  
Excision Biopsy ◽  
Upper Eyelid ◽  
Ocular Adnexa ◽  
Complete Surgical Excision ◽  
The Right

We present our findings in a case of primary neuroendocrine carcinoma (NEC) of the lacrimal gland and a case of primary Merkel cell carcinoma (MCC) of the eyelid. An 86-year-old man noticed a swelling of the left upper eyelid three months earlier. We performed excision biopsy and histopathological examination indicated that he had a primary NEC of the left lacrimal gland. He underwent chemotherapy followed by excision including the clinically visible margins and 50 Gy radiotherapy of the surgical margins. He had neither recurrence nor metastasis for 6 months since the last radiotherapy. An 80-year-old man noticed a nodule in the right upper eyelid and was referred to our hospital because the size was increasing rapidly. A complete surgical excision of the margins of the tumor was performed with histopathological confirmation of negative margins. The final diagnosis was a primary MCC of the right upper eyelid. After surgery, he underwent 50 Gy radiotherapy on the neck to prevent metastasis. No recurrence or metastasis was found for two years. Although primary NEC of the ocular adnexa is extremely rare, the tumor has high malignancy and readily metastasizes. Thus, combined therapy including surgery, radiotherapy, and/or chemotherapy is needed for complete management of NEC.

scholarly journals The arteriovenous hemangioma of the right ventricle: Case report and literature review

2019 ◽  
Vol 76 (12) ◽  
pp. 1301-1303
Author(s):  
Aleksandar Mikic ◽  
Milos Matkovic ◽  
Petar Vukicevic ◽  
Biljana Obrenovic-Kircanski ◽  
Nemanja Karamarkovic ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Right Ventricle ◽  
Surgical Excision ◽  
Long Term Results ◽  
Benign Tumors ◽  
First Line ◽  
Complete Surgical Excision ◽  
The Right

Introduction. Cardiac hemangiomas of the right ventricle are very rare and mostly asymptomatic benign tumors. The surgical excision is the first line treatment. Case report. We report a case of 69-year-old woman with an asymptomatic arteriovenous hemangioma of the right ventricle. The complete surgical excision was performed with the use of cardiopulmonary bypass and the patient was discharged on the postoperative day 6 after the uneventral postoperative course. There was no relapse during the six-month followup. Literature review revealed totally 35 cases of this tumors including our case Conclusion. Described procedure can be performed safely with the excellent long-term results.

scholarly journals Primary Tracheal Papilloma: A Case Report

2020 ◽  
Vol 49 (2) ◽  
pp. 44-47
Author(s):  
Md Hasanul Haque ◽  
Belayat Hossain Siddique ◽  
Abirvab Naha ◽  
Abdus Sattar ◽  
Nigar Sultana ◽  
...  
Keyword(s):  
Surgical Excision ◽  
Current Standard ◽  
Epithelial Tumor ◽  
Delayed Treatment ◽  
Complete Surgical Excision ◽  
Current Standard Treatment ◽  
Squamous Cell Papilloma ◽  
The Right ◽  
Specific Symptoms ◽  
Histopathological Result

Solitary papilloma in the respiratory tract is a rare benign epithelial tumor which is complete surgical excision of the current standard treatment for this type of tumor. Here a case of solitary tracheal papilloma treated by surgical resection is reported. Due to rarity and non-specific symptoms, tracheal papilloma always subjected to misdiagnosed and suffer from delayed treatment. In this case, a forty two years male has been presented with a recurrent non-productive irritative cough, a progressive shortness of breath, expiratory stridor and occasional hemoptysis. The patient was previously diagnosed as a case of bronchial asthma by a Pulmonologist and wrongly treated as well. CT scan revealed an intraluminal tracheal mass arises from the right side of the tracheal wall opposite c6-c7 vertebrae. The tumour was removed by endoscopic excision. The histopathological result confirms the diagnosis of squamous cell papilloma. No complications occur during surgery and no recurrence was observed in six months after surgery on followup. Bangladesh Med J. 2020 May; 49(2) : 44-47

Unusual presentation of granular cell tumour of buccal mucosa

2021 ◽  
Vol 14 (9) ◽  
pp. e242242
Author(s):  
Zhi Yon Charles Toh ◽  
Thomas Cooper ◽  
Maryam Jessri ◽  
Frank S-C Chang
Keyword(s):  
Buccal Mucosa ◽  
Correct Diagnosis ◽  
Granular Cell ◽  
Surgical Excision ◽  
Cell Tumour ◽  
Granular Cell Tumour ◽  
Complete Surgical Excision ◽  
Uncommon Presentation ◽  
Long Term Follow Up

Granular cell tumour (GCT) is a rare soft tissue lesion which many consider to have malignant potential of yet unknown aetiopathogenesis. Oral GCT lesions may occur in an area of leucoplakia and are predominantly present on the tongue. This case study highlights an uncommon presentation of this condition located on the buccal mucosa and illustrates the need for meticulous evaluation of suspicious lesions. Due to the malignant risk associated with GCT lesions, it is important to make the correct diagnosis and ensure complete surgical excision for these cases. Ongoing long-term follow-up is also indicated to monitor for recurrence or malignancy.

scholarly journals Amniotic membrane transplantation in surgical management of ocular surface squamous neoplasias: long-term results

Eye ◽  
2014 ◽  
Vol 28 (9) ◽  
pp. 1131-1135 ◽  
Author(s):  
M Palamar ◽  
E Kaya ◽  
S Egrilmez ◽  
T Akalin ◽  
A Yagci
Keyword(s):  
Surgical Management ◽  
Amniotic Membrane ◽  
Ocular Surface ◽  
Long Term Results ◽  
Amniotic Membrane Transplantation

scholarly journals A maxillary ameloblastic fibrosarcoma tumor: a rare case report from Syria

2020 ◽  
Vol 2020 (8) ◽  
Author(s):  
Amjad Soltany ◽  
Ghazal Asaad ◽  
Rami Daher ◽  
Mouhannad Dayoub ◽  
Ali Khalil ◽  
...  
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Rare Case ◽  
Soft Tissue Sarcomas ◽  
Surgical Excision ◽  
Low Grade ◽  
Rare Case Report ◽  
Ameloblastic Fibrosarcoma ◽  
The Right

Abstract Ameloblastic fibrosarcoma (AFS) is a rare, aggressive malignant odontogenic tumor. AFS is seen most frequently in second and third decades of life. We are reporting a case of a low grade AFS in a 21-year-old male complaining of a painless swelling in the right side of the maxilla. The patient was treated with surgical excision followed by radiotherapy, which is considered the most effective approach for most of soft tissue sarcomas. AFS has a high-reported recurrence rate (up to 37%); therefore, long-term surveillance for recurrence is crucial.

scholarly journals Thirteen-year follow-up of parasellar intravascular papillary endothelial hyperplasia successfully treated by surgical excision: case report

2015 ◽  
Vol 15 (4) ◽  
pp. 384-391 ◽  
Author(s):  
Sook Young Sim ◽  
Yong Cheol Lim ◽  
Keun Soo Won ◽  
Kyung Gi Cho
Keyword(s):  
Surgical Excision ◽  
Subtotal Resection ◽  
Intravascular Papillary Endothelial Hyperplasia ◽  
Long Term Follow Up ◽  
History Of ◽  
Papillary Endothelial Hyperplasia ◽  
The Right ◽  
Frontal Skull Base

Intracranial intravascular papillary endothelial hyperplasia (IPEH) is very rare, and to our knowledge long-term follow-up results have not been previously published. An 11-year-old boy presented with a 6-month history of progressive visual impairment in the right eye. Magnetic resonance imaging revealed a well-enhanced, large parasellar mass involving the cavernous sinus, right frontal skull base, and ethmoid and sphenoid sinuses. Frontotemporal craniotomy and subtotal resection were performed, and the diagnosis of IPEH was confirmed. The mass increased in size during the following 3 months. A second operation was performed via frontotemporal craniotomy combined with a transsphenoidal approach, and gross-total resection of the tumor was achieved. Adjuvant radiotherapy (5040 cGy) and chemotherapy with interferon were administered. The patient's visual symptoms improved, and there was no recurrence during a 13-year follow-up period. The results of this case indicate that intracranial IPEH can recur with subtotal resection; however, optimal resection with multimodal adjuvant treatment can control the disease for many years, if not permanently.

Topical Therapy for Ocular Surface Squamous Neoplasia

2013 ◽  
Vol 06 (02) ◽  
pp. 154
Author(s):  
Derek Bitner ◽  
Donald U Stone ◽  
◽  
Keyword(s):  
Ocular Surface ◽  
Topical Therapy ◽  
Genetic Defect ◽  
Surgical Excision ◽  
Treatment Modalities ◽  
Ocular Surface Squamous Neoplasia ◽  
Recurrence Rates ◽  
Interferon Alpha 2B ◽  
Complete Surgical Excision ◽  
Treatment Paradigm

Ocular surface squamous neoplasia, or OSSN, is a clinical spectrum often encountered in ophthalmic practice. The incidence varies depending on the population being studied, but is more common among less pigmented males with increased occupational ultraviolet (UV) exposure as well as among those living in closer proximity to the equator. The incidence increases with age; in younger patients, the presence of OSSN is often associated with another underlying disorder, such as the genetic defect in xeroderma pigmentosum, or immunosuppression as is seen in patients infected with HIV. The challenges of complete surgical excision in patients with extensive tumors, in addition to the high recurrence rates in some series, led to a search for nonsurgical treatment modalities. In addition to avoiding surgery, topical agents may offer the additional benefit of treating clinically unapparent disease. Due to the theoretic advantages of topical chemotherapy, multiple agents have been used in both the primary and adjuvant treatment of OSSN. Mitomycin, interferon alpha-2b, and 5-fluorouracil have all been utilized with success; mitomycin may invoke a greater risk for limbal stem cell failure, and interferon is well tolerated and effective but more expensive. Future developments in imaging and chemotherapeutics will likely continue to alter the treatment paradigm for ocular surface tumors.

scholarly journals Extraosseous Intra-Articular Osteochondroma

2013 ◽  
Vol 2013 ◽  
pp. 1-5
Author(s):  
Pragash Mohanen ◽  
Kumaresan Palania Pillai ◽  
Kanagasabai Rangasamy
Keyword(s):  
Surgical Excision ◽  
Left Knee ◽  
Bone Lesions ◽  
Excision Biopsy ◽  
Anatomic Site ◽  
Anterior Portion ◽  
Tissue Mass ◽  
Complete Surgical Excision ◽  
Biological Potential ◽  
History Of

Background. Conventional osteochondromas are common bone lesions developing in the metaphyseal region of growing skeleton. Marginal excision is the treatment of choice for such tumours. Extraosseous cartilaginous tumours are rare and their biological potential is poorly characterized.Case Presentation. A-52-year old woman presented with 3-year history of fullness and dull pain and inability to flex her left knee, sit cross-legged, or squat. Clinical and imaging studies revealed a nodular mineralised mass in the anterior portion of the knee displacing the patellar tendon laterally. Excision biopsy confirmed the diagnosis of extraosseous osteochondroma-like soft tissue mass. There is no recurrence at two-year followup.Conclusion. An integrated clinicopathological diagnosis helps to clarify the nature of extraosseous cartilaginous tumour that can arise at an unusual anatomic site. Complete surgical excision is the treatment of choice.

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