scholarly journals Respiratory syncytial virus outbreak in neonatal intensive care unit: Impact of infection control measures plus palivizumab use

2012 ◽  
Vol 1 (1) ◽  
pp. 16 ◽  
Author(s):  
Camila de A Silva ◽  
Lívio Dias ◽  
Sandra R Baltieri ◽  
Tatiane T Rodrigues ◽  
Neusa Takagi ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Respiratory Syncytial Virus ◽  
Infection Control ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Control Measures ◽  
Infection Control Measures ◽  
Syncytial Virus

Nosocomial Ringworm in a Neonatal Intensive Care Unit: A Nurse and Her Cat

2000 ◽  
Vol 21 (9) ◽  
pp. 605-607 ◽  
Author(s):  
Lewis M. Drusin ◽  
Barbara G. Ross ◽  
Karen Helton Rhodes ◽  
Alfred N. Krauss ◽  
Rachelle A. Scott
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Infection Control ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Index Case ◽  
Control Measures ◽  
Microsporum Canis ◽  
Professional Collaboration ◽  
Infection Control Measures

AbstractAn outbreak of nosocomial ringworm involved five infants in a neonatal intensive care unit. The index case was a nurse infected with Microsporum canis by her cat. After standard infection control measures were initiated, the outbreak was resolved successfully by an interdisciplinary professional collaboration of physician and veterinary dermatologists and infection control personnel.

scholarly journals Multiple Respiratory Syncytial Virus Introductions Into a Neonatal Intensive Care Unit

2020 ◽  
Author(s):  
Erica Billig Rose ◽  
Erica J Washington ◽  
Lijuan Wang ◽  
Isaac Benowitz ◽  
Natalie J Thornburg ◽  
...  
Keyword(s):  
Intensive Care ◽  
Respiratory Syncytial Virus ◽  
Infection Control ◽  
Respiratory Symptoms ◽  
Phylogenetic Trees ◽  
Neonatal Intensive Care ◽  
Control Measures ◽  
Infection Control Measures ◽  
Young Infants ◽  
Syncytial Virus

Abstract Background Outbreaks of respiratory syncytial virus (RSV) in neonatal intensive care units (NICUs) are of concern because of the risk of severe disease in young infants. We describe an outbreak of RSV in a NICU and use whole genome sequencing (WGS) to better understand the relatedness of viruses among patients. Methods An investigation was conducted to identify patients and describe their clinical course. Infection control measures were implemented to prevent further spread. Respiratory specimens from outbreak-related patients and the community were tested using WGS. Phylogenetic trees were constructed to understand relatedness of the viruses. Results Seven patients developed respiratory symptoms within an 11-day span in December 2017 and were diagnosed with RSV; 6 patients (86%) were preterm and 1 had chronic lung disease. Three patients required additional respiratory support after symptom onset, and none died. Six of 7 patients were part of the same cluster based on > 99.99% nucleotide agreement with each other and 3 unique single-nucleotide polymorphisms were identified in viruses sequenced from those patients. The seventh patient was admitted from the community with respiratory symptoms and had a genetically distinct virus that was not related to the other 6. Implementation of enhanced infection control measures likely limited the spread. Conclusions Using WGS, we found 2 distinct introductions of RSV into a NICU, highlighting the risk of healthcare-associated infections during RSV season. Early recognition and infection control measures likely limited spread, emphasizing the importance of considering RSV in the differential diagnosis of respiratory infections in healthcare settings.

scholarly journals Carbapenemase-Producing Enterobacteriaceae (CPE) Newborn Colonization in a Portuguese Neonatal Intensive Care Unit (NICU): Epidemiology and Infection Prevention and Control Measures

2021 ◽  
Vol 13 (2) ◽  
pp. 411-417
Author(s):  
Teresa L. Almeida ◽  
Tânia Mendo ◽  
Raquel Costa ◽  
Cristina Novais ◽  
Mónica Marçal ◽  
...  
Keyword(s):  
Risk Factors ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Infection Control ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Control Measures ◽  
Infection Prevention And Control ◽  
Infection Control Measures ◽  
Gut Colonization

Infections due to carbapenemase-producing Enterobacterales (CPE) are increasing worldwide and are especially concerning in a neonatal intensive care unit (NICU). Risk factors for CPE gut colonization in neonates need to be clarified. In this work, we describe the epidemiological and clinical features of CPE-colonized newborns and the infection control measures in a Portuguese NICU. We performed a prospective, observational, longitudinal, cohort study for surveillance of CPE colonization. Maternal and neonatal features of colonized newborns and surveillance strategy were described. A statistical analysis was performed with SPSS23.0, and significance was indicated by p-value ≤ 0.05. Between March and November 2019, CPE was isolated in 5.8% of 173 admitted neonates. Carbapenemase-producing Klebsiella pneumoniae were the most frequently isolated. There was no associated infection. Birth weight, gestational age, length of stay, and days of central line were the identified risk factors for CPE colonization (bivariate analysis with Student’s t-test or Mann–Whitney U test, according to normality). No independent risk factors for CPE colonization were identified in the logistic regression analysis. CPE colonization risk factors are still to be determined accurately in the neonatal population. Active surveillance and continuous infection control measures restrained the current cluster of colonized newborns and helped to prevent infection and future outbreaks.

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