scholarly journals Characterization and annotation of Babesia orientalis apicoplast genome

2015 ◽  
Vol 8 (1) ◽  
Author(s):  
Yuan Huang ◽  
Lan He ◽  
Jinfang Hu ◽  
Pei He ◽  
Junwei He ◽  
...  
Keyword(s):  
Babesia Orientalis ◽  
Apicoplast Genome

scholarly journals Nephromyces represents a diverse and novel lineage of the Apicomplexa that has retained apicoplasts

2019 ◽  
Author(s):  
Sergio A Muñoz-Gómez ◽  
Keira Durnin ◽  
Laura Eme ◽  
Christopher Paight ◽  
Christopher E Lane ◽  
...  
Keyword(s):  
Life Style ◽  
Metabolic Pathways ◽  
Evolutionary History ◽  
Phylogenetic Analyses ◽  
Phylogenetic Position ◽  
Biosynthetic Pathways ◽  
History Of ◽  
Sea Squirts ◽  
Shed Light ◽  
Apicoplast Genome

Abstract A most interesting exception within the parasitic Apicomplexa is Nephromyces, an extracellular, probably mutualistic, endosymbiont found living inside molgulid ascidian tunicates (i.e., sea squirts). Even though Nephromyces is now known to be an apicomplexan, many other questions about its nature remain unanswered. To gain further insights into the biology and evolutionary history of this unusual apicomplexan, we aimed to (1) find the precise phylogenetic position of Nephromyces within the Apicomplexa, (2) search for the apicoplast genome of Nephromyces, and (3) infer the major metabolic pathways in the apicoplast of Nephromyces. To do this, we sequenced a metagenome and a metatranscriptome from the molgulid renal sac, the specialized habitat where Nephromyces thrives. Our phylogenetic analyses of conserved nucleus-encoded genes robustly suggest that Nephromyces is a novel lineage sister to the Hematozoa, which comprises both the Haemosporidia (e.g., Plasmodium) and the Piroplasmida (e.g., Babesia and Theileria). Furthermore, a survey of the renal sac metagenome revealed 13 small contigs that closely resemble the genomes of the non-photosynthetic reduced plastids, or apicoplasts, of other apicomplexans. We show that these apicoplast genomes correspond to a diverse set of most closely related but genetically divergent Nephromyces lineages that co-inhabit a single tunicate host. In addition, the apicoplast of Nephromyces appears to have retained all biosynthetic pathways inferred to have been ancestral to parasitic apicomplexans. Our results shed light on the evolutionary history of the only probably mutualistic apicomplexan known, Nephromyces, and provide context for a better understanding of its life style and intricate symbiosis.

scholarly journals Nuclear-encoded DnaJ homologue ofPlasmodium falciparuminteracts with replicationoriof the apicoplast genome

2010 ◽  
Vol 75 (4) ◽  
pp. 942-956 ◽  
Author(s):  
Ambrish Kumar ◽  
Aiman Tanveer ◽  
Subir Biswas ◽  
Edupuganti V. S. Raghu Ram ◽  
Ankit Gupta ◽  
...  
Keyword(s):  
Apicoplast Genome

scholarly journals Sequence and Annotation of the Apicoplast Genome of the Human Pathogen Babesia microti

PLoS ONE ◽  
2014 ◽  
Vol 9 (10) ◽  
pp. e107939 ◽  
Author(s):  
Aprajita Garg ◽  
Anna Stein ◽  
William Zhao ◽  
Ankit Dwivedi ◽  
Roger Frutos ◽  
...  
Keyword(s):  
Babesia Microti ◽  
Human Pathogen ◽  
Apicoplast Genome

Development and Evaluation of Real-Time PCR Assay for the Detection of Babesia orientalis In Water Buffalo (Bubalus bubalis, Linnaeus, 1758)

2011 ◽  
Vol 97 (6) ◽  
pp. 1166-1169 ◽  
Author(s):  
Lan He ◽  
Hui-Hui Feng ◽  
Qin-Li Zhang ◽  
Wen-Jie Zhang ◽  
Muhanmad Kasib Khan ◽  
...  
Keyword(s):  
Real Time ◽  
Real Time Pcr ◽  
Water Buffalo ◽  
Bubalus Bubalis ◽  
Pcr Assay ◽  
Babesia Orientalis

A novel 53 kDa protein (BoP53) in Babesia orientalis poses the immunoreactivity using the infection serum

2020 ◽  
Vol 78 ◽  
pp. 102152
Author(s):  
Xiang Shu ◽  
Jiaying Guo ◽  
Zheng Nie ◽  
Yingjun Xia ◽  
Lan He ◽  
...  
Keyword(s):  
Babesia Orientalis

scholarly journals Mitochondrial genome of Babesia orientalis, apicomplexan parasite of water buffalo (Bubalus babalis, Linnaeus, 1758) endemic in China

2014 ◽  
Vol 7 (1) ◽  
pp. 82 ◽  
Author(s):  
Lan He ◽  
Ying Zhang ◽  
Qing-Li Zhang ◽  
Wen-Jie Zhang ◽  
Hui-Hui Feng ◽  
...  
Keyword(s):  
Mitochondrial Genome ◽  
Water Buffalo ◽  
Apicomplexan Parasite ◽  
Babesia Orientalis
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