scholarly journals Comparison of diagnostic accuracy of 2D and 3D measurements to determine opportunistic screening of osteoporosis using the proximal femur on abdomen-pelvic CT

PLoS ONE ◽  
2022 ◽  
Vol 17 (1) ◽  
pp. e0262025
Author(s):  
Sun-Young Park ◽  
Hong Il Ha ◽  
Sang Min Lee ◽  
In Jae Lee ◽  
Hyun Kyung Lim
Keyword(s):  
Femoral Neck ◽  
Diagnostic Accuracy ◽  
Correlation Coefficient ◽  
Proximal Femur ◽  
Three Dimensional ◽  
Image Plane ◽  
Outer Cortex ◽  
Perfect Agreement ◽  
Receiver Operating Characteristic Curves ◽  
Age Range

Objectives To compare the osteoporosis-predicting ability of computed tomography (CT) indexes in abdomen-pelvic CT using the proximal femur and the reliability of measurements in two- and three-dimensional analyses. Methods Four hundred thirty female patients (age range, 50–96 years) who underwent dual-energy X-ray absorptiometry and abdominal-pelvic CT within 1 month were retrospectively selected. The volumes of interest (VOIs) from the femoral head to the lesser trochanter and the femoral neck were expressed as 3DFemur. Round regions of interest (ROIs) of image plane drawn over the femoral neck touching the outer cortex were determined as 2Dcoronal. In HU histogram analysis (HUHA), the percentages of HU histogram ranges related to the ROI or VOI were classified as HUHAFat (<0 HU) and HUHABone (126 HU≤). Diagnostic performance, correlation analysis and measurement reliability were analyzed by receiver operating characteristic curves, correlation coefficient and interobserver correlation coefficient (ICC), respectively. Results AUCs of each HUHA and mean-HU measurement on 2D-ROI and 3D-VOI were 0.94 or higher (P < 0.001). Both 3DFemur-Mean-HU and 3DFemur-HUHABone showed the highest AUC (0.96). The cut-off value of 3DFemur-Mean-HU was 231HU or less, (sensitivity: 94.8%; specificity: 85.0%; correlation coefficient: −0.65; P <0.001) for diagnosis of osteoporosis. There was no superiority between AUCs in 2D-ROI and 3D-VOI measurements (P > 0.05). Reliability of the 3D-VOI measurement showed perfect agreement (ICC ≥ 0.94), and 2D-ROI showed moderate to good agreement (ICC range: 0.63~0.84). Conclusions CT indexes on 3D-VOI for predicting femoral osteoporosis showed similar diagnostic accuracy with better reproducibility of measurement, compared with 2D-ROI.

scholarly journals Three-dimensional morphological study of the proximal femur in Crowe type IV developmental dysplasia of the hip

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Yuhui Yang ◽  
Weihong Liao ◽  
Weiqun Yi ◽  
Hai Jiang ◽  
Guangtao Fu ◽  
...  
Keyword(s):  
Femoral Neck ◽  
Proximal Femur ◽  
Three Dimensional ◽  
Developmental Dysplasia ◽  
Medullary Canal ◽  
Femoral Offset ◽  
Neck Shaft Angle ◽  
Type Iv ◽  
Shaft Angle ◽  
Dysplasia Of The Hip

Abstract Background When performing femoral reconstruction in patients with Crowe type IV developmental dysplasia of the hip (DDH), anatomical deformity presents many technical challenges to orthopedic surgeons. The false acetabulum is suggested to influence load transmission and femoral development. The aim of this study was to describe the morphological features of dysplastic femurs in Crowe type IV DDH and further evaluate the potential effect of the false acetabulum on morphological features and medullary canal of Crowe type IV femurs. Methods We analyzed preoperative computed tomography scans from 45 patients with 51 hips (25 hips without false acetabulum in the IVa group and 26 hips with false acetabulum in the IVb group) who were diagnosed with Crowe type IV DDH and 30 normal hips in our hospital between January 2009 and January 2019. Three-dimensional reconstruction was performed using Mimics software, and the coronal femoral plane was determined to evaluate the following parameters: dislocation height, dislocation ratio, height of the femoral head (FH), height of the greater trochanter (GT), GT–FH height discrepancy, height of the isthmus, neck-shaft angle, femoral offset and anteversion of the femoral neck. The mediolateral (ML) width, anterolateral (AP) width and diameter of medullary canal of the proximal femur were measured on the axial sections. Further, canal flare index (CFI), metaphyseal-CFI and diaphyseal-CFI were also calculated. Results Compared with the normal femurs, the Crowe type IV DDH femurs had a higher femoral head, larger GT–FH height discrepancy, larger femoral neck anteversion, higher isthmus position and smaller femoral offset. Dislocation height and dislocation rate were significantly larger in the IVa DDH group (65.34 ± 9.83 mm vs. 52.24 ± 11.42 mm). Further, the IVb femurs had a significantly lower isthmus position, larger neck-shaft angle and smaller femoral neck anteversion than IVa femurs. The ML, AP canal widths and the diameter of medullary canal in both DDH groups were significantly smaller than the normal group. Dimensional parameters of IVa femurs were also narrower than IVb femurs in most sections, but with no difference at the level of isthmus. According to the CFIs, the variation of proximal medullary canal in IVb femurs was mainly located in the diaphyseal region, while that in IVa femurs was located in the whole proximal femur. Conclusions High dislocated femurs are associated with more anteverted femoral neck, smaller femoral offset and narrower medullary canal. Without stimulation of the false acetabulum, IVa DDH femurs were associated with higher dislocation and notably narrower medullary canal, whose variation of medullary canal was located in the whole proximal femur.

scholarly journals Three-Dimensional Morphological Analysis of the Femoral Neck Torsion Angle - An Anatomical Study

2020 ◽  
Author(s):  
Ru-yi Zhang ◽  
Xiu-yun Su ◽  
Jing-xin Zhao ◽  
Jian-tao Li ◽  
Li-cheng Zhang ◽  
...  
Keyword(s):  
Femoral Neck ◽  
Cross Section ◽  
Proximal Femur ◽  
Torsion Angle ◽  
Measurement Method ◽  
Three Dimensional ◽  
Coronal Plane ◽  
Femoral Neck Axis ◽  
Significant Difference ◽  
Neck Torsion

Abstract Background: The femoral neck torsion angle (FNTA) is an important but often neglected parameter in assessments of the anatomical morphology of the femoral neck, which is often confused with the femoral neck anteversion angle (FNAA) in the current literature. Currently, the measurement methods reported in the literature all adopt the naked eye or two-dimensional (2D) visualization method, and the measurement parameters and details are not clearly defined. The objection of this research was to provide a reliable 3D method for determining the femoral neck axis, to improve the measurement method of the FNTA, and to analyze the anatomical and clinical significance of the results.Methods: Computed tomography (CT) data of 200 patients who received a lower extremity CT angiography examination were selected, and the bilateral femurs were reconstructed with three dimensional CT (3D CT). First, the 3D axis of the femoral neck was built. Second, the long axis of the cross section the femoral neck isthmus (FNI) and femoral neck basilar part (FNB) were confirmed by the “inertia axes” method, and the plane consisting of the long axis of the cross-section and the center of the femoral head was defined as the long axial plane. Third, the coronal plane of the proximal femur was determined through the long axis of the proximal femur and the femoral coronal. Finally, the FNTAs (the angles between the long axial planes and the coronal plane of the proximal femur) of FNI and FNB were measured. The size of FNTA was compared between the sexes and sides and different locations, the correlation between the parameters and age, height and weight were evaluated.Results: The difference in FNTA was statistically significant between the isthmus and the basilar part (isthmus 30.58 ± 8.90° vs. basilar part 23.79 ± 3.98°; p < 0.01). Significant difference in the FNTA was observed between the sexes (males 31.99 ± 9.25° vs. females 27.49 ± 7.19°; p < 0.01). The increase in FNTA from the basilar part to the isthmus was 6.79 ± 8.06°, and the male (7.87 ± 8.57°) was greater than the female (4.44 ± 6.23°, p < 0.01). However, no significant difference in the values was observed between sides. Height exerted the greatest effect on the FNTA according to the correlation analysis (r = 0.255, p＜0.001). Conclusions: This study found a reliable 3D method for the determination of the femoral neck axis improved the measurement method of the FNTA and made it more accurate and repeatable. The results provided a methodological basis and theoretical support for the research and development of internal fixation device for femoral neck fracture and the spatial configuration of implants in treatment. And, the optimal opening point of the femoral medullary cavity was recommended to locate at the posterior position of the top of the femoral neck cross-section during hip replacement.

Measurements in 3D images

1991 ◽  
Vol 49 ◽  
pp. 408-409
Author(s):  
John C. Russ
Keyword(s):  
Three Dimensional ◽  
Image Plane ◽  
X Rays ◽  
Traditional Use ◽  
3D Images ◽  
Confocal Scanning Laser Microscope ◽  
Hard Materials ◽  
Depth Direction ◽  
Confocal Scanning ◽  
Confocal Scanning Laser

Three-dimensional (3D) images consisting of arrays of voxels can now be routinely obtained from several different types of microscopes. These include both the transmission and emission modes of the confocal scanning laser microscope (but not its most common reflection mode), the secondary ion mass spectrometer, and computed tomography using electrons, X-rays or other signals. Compared to the traditional use of serial sectioning (which includes sequential polishing of hard materials), these newer techniques eliminate difficulties of alignment of slices, and maintain uniform resolution in the depth direction. However, the resolution in the z-direction may be different from that within each image plane, which makes the voxels non-cubic and creates some difficulties for subsequent analysis.

A comparison between the CS-TOF and the CTA/DSA for WEB device management

2021 ◽  
pp. 159101992110147
Author(s):  
Oktay Algin ◽  
Gokhan Yuce ◽  
Ural Koc ◽  
Gıyas Ayberk
Keyword(s):  
Mr Angiography ◽  
Three Dimensional ◽  
Morphological Parameters ◽  
Perfect Agreement ◽  
Device Management ◽  
Web Device ◽  
Sensing Time ◽  
The Web

Purpose There is no study on the role of three-dimensional compressed sensing time of flight MR angiography (3D-CS-TOF) in the management of the WEB device. We evaluated the efficacy of 3-tesla 3D-CS-TOF for the management and follow-up of the WEB device implantations. Materials and methods Seventy-three aneurysms of 69 patients treated with the WEB device were retrospectively examined. Morphological parameters and embolization results of the aneurysms were assessed and compared on 3D-CS-TOF, CTA, and DSA images. Results Occluded, neck remnant, and recurrent aneurysms were observed in 61 (83.6%), 7 (9.6%), and 5 (6.8%) aneurysms, respectively. Inter- and intra-reader agreement values related to aneurysm size measurements were perfect. Aneurysms size, age, and proximal vessel tortuosity were negatively correlated with the visibility of the aneurysms and parent vessels on 3D-CS-TOF images (p = 0.043; p = 0.032; p < 0.001, respectively). Subarachnoid hemorrhage and age are associated with 3D-CS-TOF artifacts (p = 0.031; p = 0.005, respectively). 3D-CS-TOF findings are in perfect agreement with DSA or CT angiography (CTA) results (p < 0.001). Conclusion According to our results, 3D-CS-TOF can be an easy, fast, and reliable alternative for the management or follow-up of WEB assisted embolization.

Ultrasonographic 3D Evaluation in the Diagnosis of Bladder Endometriosis: A Prospective Comparative Diagnostic Accuracy Study

2021 ◽  
pp. 1-8
Author(s):  
Fabio Barra ◽  
Franco Alessandri ◽  
Carolina Scala ◽  
Simone Ferrero
Keyword(s):  
Diagnostic Accuracy ◽  
Three Dimensional ◽  
3D Ultrasound ◽  
Diagnostic Accuracy Study ◽  
Extensive Experience ◽  
Deep Endometriosis ◽  
3D Reconstructions ◽  
Analysis Group ◽  
Bladder Endometriosis ◽  
Accuracy Study

<b><i>Objective:</i></b> The use of three-dimensional (3D) transvaginal ultrasonography (TVS) has been investigated for the diagnosis of deep endometriosis (DE). This study aimed to evaluate if 3D reconstructions improve the performance of TVS) in assessing the presence and characteristics of bladder endometriosis (BE). <b><i>Design:</i></b> This was a single-center comparative diagnostic accuracy study. <b><i>Participants/Materials, Setting, Methods:</i></b> Patients referred to our institution (Piazza della Vittoria 14 Srl, Genova, Italy) with clinical suspicion of DE were included. In case of surgery, women underwent systematic preoperative ultrasonographic imaging; an experienced sonographer performed a conventional TVS; another experienced sonographer, blinded to results of the previous exam, performed TVS, with the addition of 3D modality. The presence and characteristics of BE nodules were described in accord with International DE Analysis group consensus. Ultrasound data were compared with surgical and histological results. <b><i>Results:</i></b> Overall, BE was intraoperatively found in 34 out of 194 women who underwent surgery for DE (17.5%; 95% confidence interval: 12.8–23.5%). TVS without and with 3D reconstructions were able to detect endometriotic BE in 82.2% (<i>n</i> = 28/34) and 85.3% (<i>n</i> = 29/34) of the cases (<i>p</i> = 0.125). Both the exams similarly estimated the largest diameter of BE (<i>p</i> = 0.652) and the distance between the endometriotic nodule and the closest ureteral meatus (<i>p</i> = 0.341). However, TVS with 3D reconstructions was more precise in estimating the volume of BE (<i>p</i> = 0.031). In one case (2.9%), TVS without and with 3D reconstructions detected the infiltration of the intramural ureter, which was confirmed at surgery and required laparoscopic ureterovesical reimplantation. <b><i>Limitations:</i></b> The extensive experience of the gynecologists performing the ultrasonographic scans, the lack of prestudy power analysis, and the population selected, which may have been influenced by the position of the institution as a referral center specialized in the treatment of severe endometriosis, are limitations of the current study. <b><i>Conclusion:</i></b> Our results demonstrated the high accuracy of ultrasound for diagnosing BE. The addition of 3D reconstructions does not improve the performance of TVS in diagnosing the presence and characteristics of BE. However, the volume of BE may be more precisely assessed by 3D ultrasound.

scholarly journals Superconformal boundaries in 4 − ϵ dimensions

2021 ◽  
Vol 2021 (4) ◽  
Author(s):  
Aleix Gimenez-Grau ◽  
Pedro Liendo ◽  
Philine van Vliet
Keyword(s):  
Three Dimensional ◽  
Spacetime Dimension ◽  
Perfect Agreement ◽  
Bootstrap Analysis ◽  
First Order ◽  
Free Theory ◽  
First Order Correction ◽  
Free Parameters ◽  
Superconformal Theories ◽  
Zumino Model

Abstract Boundaries in three-dimensional $$ \mathcal{N} $$ N = 2 superconformal theories may preserve one half of the original bulk supersymmetry. There are two possibilities which are characterized by the chirality of the leftover supercharges. Depending on the choice, the remaining 2d boundary algebra exhibits $$ \mathcal{N} $$ N = (0, 2) or $$ \mathcal{N} $$ N = (1) supersymmetry. In this work we focus on correlation functions of chiral fields for both types of supersymmetric boundaries. We study a host of correlators using superspace techniques and calculate superconformal blocks for two- and three-point functions. For $$ \mathcal{N} $$ N = (1) supersymmetry, some of our results can be analytically continued in the spacetime dimension while keeping the codimension fixed. This opens the door for a bootstrap analysis of the ϵ-expansion in supersymmetric BCFTs. Armed with our analytically-continued superblocks, we prove that in the free theory limit two-point functions of chiral (and antichiral) fields are unique. The first order correction, which already describes interactions, is universal up to two free parameters. As a check of our analysis, we study the Wess-Zumino model with a super-symmetric boundary using Feynman diagrams, and find perfect agreement between the perturbative and bootstrap results.

scholarly journals High-resolution three-dimensional microstructural analysis of cortex of the superolateral femoral neck in men reveals critical subregion

Bone Reports ◽  
2021 ◽  
Vol 14 ◽  
pp. 100964
Author(s):  
Ana Cirovic ◽  
Aleksandar Cirovic ◽  
Vladimir Zivkovic ◽  
Slobodan Nikolic ◽  
Petar Milovanovic ◽  
...  
Keyword(s):  
High Resolution ◽  
Femoral Neck ◽  
Microstructural Analysis ◽  
Three Dimensional

Differences in proximal femur geometry distinguish vertebral from femoral neck fractures in osteoporotic women

2004 ◽  
Vol 77 (915) ◽  
pp. 219-223 ◽  
Author(s):  
S Gnudi ◽  
N Malavolta ◽  
D Testi ◽  
M Viceconti
Keyword(s):  
Femoral Neck ◽  
Proximal Femur ◽  
Femoral Neck Fractures ◽  
Femur Geometry

A Study of Machiavellianism and Emotional Intelligence in Adolescents

2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Dr Nalini Malhotra
Keyword(s):  
Emotional Intelligence ◽  
Regression Analysis ◽  
Correlation Coefficient ◽  
Random Sampling ◽  
Negative Relationship ◽  
Intelligence Scale ◽  
Significant Contributor ◽  
Age Range

The present paper seeks to investigate the Machiavellianism in relation with Emotional Intelligence among Adolescents. It was hypothesized that Machiavellianism and Emotional Intelligence would be negatively correlated and Emotional Intelligence would be a significant contributor in predicting variance in Machiavellianism. In order to test the hypothesis 240 adolescents (120 females and 120 males) in the age range of 13 to 18 years were selected through random sampling. The measures used were Machiavellianism Scale (Mach IV Scale) and Modified Schutte Emotional Intelligence Scale (Schutte 1998). The correlation coefficient and regression analysis were used to assess the data. The results revealed significant and negative relationship between Machiavellianism and Emotional Intelligence .Emotional Intelligence emerged as a significant predictor of Machiavellianism. Thus, considering the possibility that individuals might have a dispositional tendency to emotionally manipulative behaviour immediately brings to mind the trait of Machiavellianism.

Morphometric Parameters of the Proximal Femur in Nepalese Population: A Cross-sectional Study

2020 ◽  
Vol 3 (2) ◽  
pp. 8-12
Author(s):  
Bishnu Pokharel ◽  
Ashok Raj Pant ◽  
Pashupati Chaudhary ◽  
Guru Prasad Khanal
Keyword(s):  
Femoral Neck ◽  
Proximal Femur ◽  
Cross Sectional Study ◽  
Morphometric Parameters ◽  
Radiographic Measurement ◽  
Sectional Study ◽  
Cross Sectional ◽  
Neck Width ◽  
Femur Fractures ◽  
Femoral Neck Width

Background: Most of the proximal femur fractures are managed surgically by internal fiation with a variety of implants. Improperly designed or ill-fited implant may lead to a failure of fiation, breakage of implant and nonunion, thus increasing the morbidity and the cost of treatment. This study was conducted to evaluate the radiographic morphometry of the proximal femur which may be helpful in designing the implants for the Nepalese population. Methods: In this cross-sectional study, 84 patients aged 18 years and above with traumatic unilateral hip fracture were enrolled. Anthropometric measurements were recorded. The postoperative check X-ray in the antero-posterior view of the pelvis and bilateral hip were assessed. Various morphometric parameters of the proximal femur were measured and recorded in the radiograph of the unaffcted limb using a digital caliper. Results: Out of 84 patients, 47 were male. The mean ± SD femoral neck width, femoral neck length, femoral axis length, cervico-diaphyseal angle, acetabular tear-drop distance, and great trochanter-pubic symphysis distance were 36.10 ± 5.67 mm, 28.29 ± 4.18 mm, 104.51 ± 9.56 mm, 130.35 ± 8.67°, 32.56 ± 11.05 mm, and 163.07 ± 10.71 mm respectively. The femoral neck width was found to be signifiantly larger in males (39.08 ± 3.06 mm) than in females (32.32 ± 5.99 mm, p < 0.001). Conclusion: This study determined the radiographic measurement of the proximal femur and found that the femoral neck width of the males was larger than that of the females.

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