scholarly journals Multiparameter Biosignal Analysis in Elderly Ischemic Stroke Patients

2021 ◽  
Vol 1 (1) ◽  
pp. 7-16
Author(s):  
Muhammad Zakariyah ◽  
Alvin Sahroni ◽  
Erlina Marfianti
Keyword(s):  
Ischemic Stroke ◽  
Control Group ◽  
P Value ◽  
Stroke Patients ◽  
Physiological Conditions ◽  
Biosignal Analysis ◽  
Nervous System Activity ◽  
Stroke Group ◽  
The Relationship ◽  
The Brain

Biosignal can provide information about body conditions, including physiological conditions of ischemic stroke. The regulation of blood in the brain is regulated through the mechanism of Cerebral Autoregulation (CA). Some parameters that can be used to determine this mechanism are Blood Flow Velocity (BFV) and Blood Pressure (BP). Stroke is also related to nervous system activity, which is represented through the Heart Rate Variability (HRV). This study aims to determine the relationship between those biosignals and their effects on the physiology of ischemic stroke sufferers. The subjects were divided into two groups (20 strokes and 20 controls). BFV data is obtained in the Middle Cerebral Artery (MCA), BP is obtained through the arteries of the upper arms, and 3 leads electrocardiogram is placed in the chest. The results showed that there was a relationship between BP and BFV in the control group (p-value < 0.05; r = -0.574). This correlation was not found in the stroke group. The relationship between BP and HRV was only found in the stroke group, which was associated with high sympathetic activity and lower parasympathetic activity (p-values < 0.05 and r > 0.4). It was based on SDRR, RMSSD, CVRR, LF, and SD1 parameters. In the control group, there was no relationship between HRV and BP. The relationship between BFV and HRV in the control group was not found statistically. Still, in the stroke group, this relationship was found in the LF and LF/HF Ratio parameters (p-value < 0.05; r > 0.4). Based on this research, parameters on HRV that can be used to determine the characteristics of stroke patients in all positions are MeanRR, VLF, and LF

scholarly journals Abnormal EEG Complexity and Functional Connectivity of Brain in Patients with Acute Thalamic Ischemic Stroke

2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Shuang Liu ◽  
Jie Guo ◽  
Jiayuan Meng ◽  
Zhijun Wang ◽  
Yang Yao ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Functional Connectivity ◽  
Healthy Subjects ◽  
Brain Network ◽  
Control Group ◽  
Stroke Patients ◽  
Cerebral Disease ◽  
Essential Information ◽  
Stroke Group ◽  
The Brain

Ischemic thalamus stroke has become a serious cardiovascular and cerebral disease in recent years. To date the existing researches mostly concentrated on the power spectral density (PSD) in several frequency bands. In this paper, we investigated the nonlinear features of EEG and brain functional connectivity in patients with acute thalamic ischemic stroke and healthy subjects. Electroencephalography (EEG) in resting condition with eyes closed was recorded for 12 stroke patients and 11 healthy subjects as control group. Lempel-Ziv complexity (LZC), Sample Entropy (SampEn), and brain network using partial directed coherence (PDC) were calculated for feature extraction. Results showed that patients had increased mean LZC and SampEn than the controls, which implied the stroke group has higher EEG complexity. For the brain network, the stroke group displayed a trend of weaker cortical connectivity, which suggests a functional impairment of information transmission in cortical connections in stroke patients. These findings suggest that nonlinear analysis and brain network could provide essential information for better understanding the brain dysfunction in the stroke and assisting monitoring or prognostication of stroke evolution.

scholarly journals Peningkatan Kadar Lipoprotein-Associated Phospholipase A2 Meningkatkan Kejadian Stroke Iskemik Akut

2020 ◽  
Vol 3 (1) ◽  
pp. 09-13
Author(s):  
Syarif Indra
Keyword(s):  
Ischemic Stroke ◽  
Serum Levels ◽  
High Serum ◽  
Control Group ◽  
P Value ◽  
Stroke Patients ◽  
Cross Sectional ◽  
Major Health Problem ◽  
The World ◽  
Stroke Group

Introduction: Stroke is a major health problem in the world, and associated with mortality, disability, and economic burden. Stroke is the second leading cause of death in the world after heart disease and cause of disability in adults. Several recent studies show that levels of Lp-PLA2 contribute to high serum lead to ischemic stroke, whereas some others do not get the association. Aims: studies an association between serum Lp-PLA2 with incident ischemic stroke. Method: This study is a descriptive analytic comparative with cross sectional design in the Neurology ward RS. DR. M. Djamil Padang between October 2013 to April 2014 with total of 88 subjects consisting of 44 subjects ischemic stroke patients and 44 healthy control group who participated in the study. Statistical analysis is used parametric test with unpaired t test, test for normality with the Kolmogorov-Smirnov test, and logistic regression analysis. Result: P value 0.05 was considered statistically significant. The mean age of subjects in the group of ischemic stroke patients was 57.30 ±8.86 years old. Female in patients with ischemic stroke group was 23 people (52,3%). Mean levels of Lp-PLA2 serum in patiens with ischemic stroke group was 103.49±48.00 ng/mL. A significan association between serum levels of Lp-PLA2 with incident ischemic stroke with p<0.05. Conclusion: There was a significant relation in elevation of serum Lp-PLA2 levels with incident of ischemic stroke.

The effect of additional protein, phosphatidylcholine, phosphatidylserine, and inulin on S100β levels of acute ischemic stroke patients at Dr. Kariadi Central Hospital, Semarang

2021 ◽  
Vol 9 (2) ◽  
pp. 172-183
Author(s):  
Stephani Nesya Renamastika ◽  
Endang Mahati ◽  
Martha Kartasurya ◽  
Dodik Pramukarso ◽  
Dwi Pudjonarko ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
G Protein ◽  
Intervention Group ◽  
Nerve Cells ◽  
Control Group ◽  
Stroke Patients ◽  
Formula Milk ◽  
Blood Brain ◽  
Additional Protein ◽  
The Brain

Background: The brain releases biochemical substrates, such as S100β protein, into circulation in response to ischemic conditions as a sign of damage in nerve cells and disruption of the blood-brain barrier’s integrity. Thrombolytic therapy has led to the development of many neuroprotective therapies such as protein, phosphatidylcholine, phosphatidylserine, and inulin, which can be added to food products. Protein, phospholipids, and inulin, have a neuroprotective impact on nerve cells in the brain and blood-brain barrier.Objective: To prove the effect of protein, phosphatidylcholine, phosphatidylserine, and inulin on S100β levels and clinical outcomes in patients with acute ischemic stroke.Materials and Methods: This study was done in a single-blind RCT. Eighteen ischemic stroke patients were randomly divided into nine subjects for the intervention group and nine subjects for the control group. The Control group received 250 ml conventional formula milk (11.8 g protein) 3 times/day. The intervention group received 250 mL commercial milk 3 rimes/day which contained 15 g protein with 128 mg phosphatidylcholine, 32 mg phosphatidylserine, and 3 g inulin. All of the groups were given hospital-standard therapy for ischemic stroke. S100β levels were measured at pre and post-intervention.Results: Pre and post S100β levels in intervention and the control group did not show any statistically difference (p = 0.777 and p = 0.096), but there was a trend of decreasing  levels of S100β in the intervention group (-24.6 + 252.0 pg/mL) versus control group (135.8 + 216.2 pg/mL).Conclusions: The addition of protein, phosphatidylcholine, phosphatidylserine, and inulin did not have a significant effect on S100β levels.

scholarly journals Range Of Motion (ROM) Spherical Grip dapat Meningkatkan Kekuatan Otot Ekstremitas Atas Pasien Stroke

2018 ◽  
Vol 6 (1) ◽  
pp. 38-48
Author(s):  
Gina Dwi Anggraini ◽  
Septiyanti Septiyanti ◽  
Dahrizal Dahrizal
Keyword(s):  
Range Of Motion ◽  
Intervention Group ◽  
Clinical Manifestations ◽  
The Body ◽  
Control Group ◽  
P Value ◽  
Stroke Patients ◽  
Muscle Testing ◽  
The Difference ◽  
The Brain

Stroke is lost brain function caused by stop his blood supply to the brain. As a result of the disruption of oxygen to the brain needs can occur the clinical manifestations included the weakness of some or all of the body limbs, one of over ekstremities so that the patient could not doing the activity because of the limbs weakness and they needs exercise for preveting disability. Objective is Know the effect of Range Of Motion (ROM) Spherical Grip on muscle strenght of upper extremity on stroke patients. The research used quasi-experimental with pretest and posttest with control group. The population in this study is all stroke patients in the neurological specialist RSUD dr. M. Yunus of Bengkulu City. The Sampling technique used is Cluster Sampling. The number of sample is 32. Instruments used for manual muscle testing. Test for normality using the Kolmogorov-Smirnov and analysis techniques using Wilcoxon Signed Ranks Test  and Mann-Whitney with 95% confidence level (  = 0,05). Muscle strenght of the finger mean in the control group 2,44 increase to 2,63 with the difference 0,1875. In the intervention group mean 2,44 increase to 3,13 with the difference 0,6875. Muscle strenght of the wrist mean in the control group 2,38 increase to 2,56 with the difference 0,1875. In the intervention group mean 2,25 increase to 3,00 with the difference 0,75. The result obtained p-value 0,011 finger hand and p-value 0,027 wrist. Exercise Range Of Motion (ROM) Spherical Grip is effective in increase muscle strenght of over extremities on stroke patients.

scholarly journals COMPARISON OF COGNITIVE FUNCTION BETWEEN FIRST ISCHEMIC STROKE AND RECURRENT ISCHEMIC STROKE PATIENTS

2022 ◽  
Vol 8 (1) ◽  
pp. 30-34
Author(s):  
Fildza Intan Rizkia ◽  
Chandra Calista ◽  
Suryani Gunadharma ◽  
Asep Nugraha Hermawan ◽  
Lisda Amalia ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Cognitive Impairment ◽  
Cognitive Function ◽  
Recurrent Stroke ◽  
Demographic Data ◽  
P Value ◽  
Stroke Patients ◽  
Cross Sectional ◽  
Significant Difference ◽  
Stroke Group

Background: Cognitive impairment is a common condition that may affect up to 50% of stroke patients. Post stroke cognitive impairment is associated with reduced quality of life, which may increase the number of dependency. Recurrent stroke may happen in approximately 25% patients and they have higher rates of cognitive impairment. Objective: The aim of this study is to examine the comparison of cognitive function between first ischemic stroke and recurrent ischemic stroke patients in Hasan Sadikin Hospital, Bandung. Methods: This study is a retrospective, cross-sectional study using the data recruited between the year 2012 - 2016 at the Department of Neurology at the Hasan Sadikin Hospital Bandung. The data collected in this study were demographic data, including age, level of education, and residence, and the clinical data as well. Cognitive function was assessed using Mini-Mental State Examination (MMSE). The comparison between the cognitive function between both groups were analyzed using the Mann-Whitney U test. Results: There were 428 subjects eligible for this study, with 207 subjects categorized as first ischemic stroke group and 221 subjects categorized as recurrent ischemic stroke group. There was a statistically significant difference in MMSE scores between the first ischemic stroke patients (24.90 ± 4.64) and recurrent ischemic stroke patients (22.85 ± 4.64 ) with a p value of 0.002. Conclusion: Recurrent ischemic stroke patients had lower MMSE scores than the first ischemic stroke patients. Clinicians should be more aware in detecting early cognitive impairment in stroke patients and in preventing the incidence of recurrent stroke.

scholarly journals Pengaruh hidroterapi rendam kaki air hangat terhadap kekuatan otot pada pasien stroke non hemoragik

2019 ◽  
Vol 8 (1) ◽  
Author(s):  
Setiyawan Setiyawan ◽  
Lina Pratiwi ◽  
Noerma Shovie Rizqiea
Keyword(s):  
Muscular Strength ◽  
Hemorrhagic Stroke ◽  
Blood Clot ◽  
Intervention Group ◽  
Control Group ◽  
P Value ◽  
Stroke Patients ◽  
Control Group Design ◽  
Quasi Experimental ◽  
The Brain

Non-hemorrhagic stroke is a disease which is related to a functional disorder of the brain due to the blood vessel blockage by a blood clot, or by the narrowing of an artery or some arteries that lead to the brain which causes weakness of muscular strength. One of the non-pharmacological therapies, which are beneficial to non-hemorrhagic stroke patients, is hydrotherapy. Hydrotherapy is a therapy which utilizes water to cure or relieve various complaints. One of which is the complaint of how to strengthen muscular strength. The objective of this research is to investigate the effect of warm footbath hydrotherapy to increase the muscular strength of non-hemorrhagic stroke patients. This research used the quasi-experimental research method ith pre-test and post-test nonequivalent control group design. Non-probability sampling with purposive sampling was used to determine its samples. The samples consisted of 40 respondents, into two groups: intervention and control group. The data of the research were analyzed by using the Wilcoxon’s Test and Mann Whitney’s Test. The result of the research shows that the footbath hydrotherapy had an effect on the muscular strength of the non-hemorrhagic stroke patients as indicated by the p-value = 0.000, and there was a difference between the control group and the intervention group where the p-value was 0. 008. The footbath hydrotherapy affected the muscular strength of non-hemorrhagic stroke patients. Thus, nurses as health practitioners are expected to administer warm footbath hydrotherapy to increase the muscular strength of non-hemorrhagic stroke patients.

scholarly journals Serum magnesium levels in patients of ischemic stroke and its correlation with neurological disability

2020 ◽  
Vol 8 (4) ◽  
pp. 1241
Author(s):  
Vishali Kotwal ◽  
Rajesh Maini
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Glutamate Release ◽  
Serum Magnesium ◽  
Normal Subjects ◽  
Control Group ◽  
P Value ◽  
Stroke Patients ◽  
Neurological Disability ◽  
Neuroprotective Effects

Background: Stroke is a leading cause of death and disability worldwide acute ischaemic stroke accounts for 87% of strokes and mostly affects persons at the peak of their lives. Magnesium is known to have neuroprotective effects in ischemic stroke through a variety of mechanisms including decrease in glutamate release and inhibition of NMDA receptors and vasodilation. Previous studies on serum magnesium levels in stroke patients have shown variable results with many of them finding lower levels than in normal subjects. This study was undertaken to compare serum magnesium levels in patients of acute ischemic stroke with those of controls and also find a correlation if any between serum magnesium levels and neurological disability.Methods: This was a prospective non-interventional case-control study in which 50 patients of acute ischemic stroke in the age group of 20 to 80 years admitted in the department of Medicine Government Medical College Jammu from October 2019 to January 2020 were taken. Their serum magnesium levels were analysed within first 24 hours of admission and neurological disability was measured using modified Rankin Score. Serum magnesium levels were also estimated in 35 healthy controls for comparison.Results: Serum magnesium was lower in the study group (mean of 1.85±0.36) as compared to the control group (mean of 2.4±0.21) which was statistically significant (p value =0.001). Modified Rankin Score was 4 to 5 in 27 patients and 2 to 3 in 23 patients and it was negatively correlated with serum magnesium levels (r =-0.67).Conclusions: Ischemic stroke patients had lower serum magnesium levels as compared to healthy subjects in our study and also lower levels were seen in those with higher neurological disability.

FIBRINOGEN DAN TRANSCRANIAL DOPPLER DI STROK ISKEMIK AKUT

2016 ◽  
Vol 21 (3) ◽  
pp. 280
Author(s):  
Hafizah Soraya Dalimunthe ◽  
Adi Koesoema Aman ◽  
Yuneldi Anwar
Keyword(s):  
Ischemic Stroke ◽  
Transcranial Doppler ◽  
Pearson Correlation ◽  
Control Group ◽  
Mean Velocity ◽  
Diastolic Velocity ◽  
Stroke Group ◽  
The Mean ◽  
And Control ◽  
The Relationship

Elevated fibrinogen levels is related to the blood hyperviscosity, that causes low blood velocity. Non-contrast-enhanced transcranial Doppler (TCD) is used to evaluate blood flow from the cerebrovascular system. To know the relationship between fibrinogen levels and examination of TCD in acute ischemic stroke through evaluation. A cross sectional study was admitted from July 2012-Juny 2013. The researchers determined the differences between fibrinogen and TCD in the stroke group and control. The researchers examined the relationship between fibrinogen and TCD examination in the stroke group. The fibrinogenwas measured with Clauss method. The TCD was examined due to middle of the cerebral artery (MCA) and the Internal Carotid one Artery (ICA). The patients were diagnosed as ischemic stroke from head CT-scan. Statistical analyses employed the Independent T test, Anova test and Pearson correlation. The researchers had 24 patients and 24 controls that the Fibrinogen levels in stroke group is 549.16±104.84 mg/mL and in the control group is 385.64±16.80 mg/mL. The researchers examined MCA in the stroke as well as the control and found the mean velocity 43.12±21.03and 56.97±6.22 (p=0.05), the peak velocity 74.17±32.58 and 94.55±14.11 (p=0.05) end diastolic velocity 23.27±12.66 and 35.30±7.34 (p=0.00). In ICA, the stroke group and control and found the mean velocity 31.40±8.86 and 43.07±8.06 (p=0.00), thepeak velocity 54.99±11.50 and 75.04±16.04 (p=0.00) end diastolic velocity 18.23±7.67 and 25.64±5.24 (p=0.00). The correlation between fibrinogen and TCD in the stroke group was not significant on MCA and ICA, P>0.05. It can be concluded that the differences between fibrinogen levels and TCD in the stroke group and control are significant. But there is no correlation between the fibrinogen and TCD in the stroke group.

scholarly journals Gabapentin and Amitriptilin Treatment toward Living Quality of Post Ischemic Stroke Patients with Neurophaty Pain

2015 ◽  
Vol 4 (4) ◽  
pp. 250
Author(s):  
Pinasti Utami ◽  
Zulies Ikawati ◽  
Setyaningsih Setyaningsih
Keyword(s):  
Ischemic Stroke ◽  
Brief Pain Inventory ◽  
The Body ◽  
P Value ◽  
Stroke Patients ◽  
Significant Difference ◽  
Quasi Experimental ◽  
The Brain

Stroke becomes a significant problem for developing countries. In Indonesia the data show its incidences 234 per 100.000 people, and around 2 - 8 % stroke patients experiencing cerebrovascular session will get neurophaty pain. It happens because of sensoric deviation after stroke, so the brain does not completely send information to the body correctly. Patients experiencing neurophaty pain are able to face decreasing living quality as the effect of long term painful disturbance. Therefore, it is important to maintain the patients’ living quality. The aim of the study is to investigate the comparison of using gabapentin and amitriptilin toward living quality of ischemic stroke patients with neurophaty pain in the hospitals in Jogja. The method used in this study was quasi experimental with consequtive sampling. The study was conducted on 22nd of April-31st of Juli 2013 by involving 23 patients in gabapentin group and 18 patientsin amitriptilin group that would be evaluated during 1 month. Living quality was assessed by Brief Pain Inventory (BPI) in week 0 and week 4. The result of the study showed that the use of gabapentin and amitriptilin in 4 weeks showed the increase of living quality represented by decreasing the score based on BPI questioner 1.67±0.78 and 1.37±0.80 with p-value>0.05 meaning that there was no significant difference. It can be concluded the comparison of using gabapentin and amitriptilin in post ischemic stroke patient with neuropathy pain not significantly increase the quality of in the hospitals in Jogja.

Gabapentin and Amitriptilin Treatment toward Living Quality of Post Ischemic Stroke Patients with Neurophaty Pain

2015 ◽  
Vol 4 (4) ◽  
pp. 250
Author(s):  
Pinasti Utami ◽  
Zulies Ikawati ◽  
Setyaningsih Setyaningsih
Keyword(s):  
Ischemic Stroke ◽  
Brief Pain Inventory ◽  
The Body ◽  
P Value ◽  
Stroke Patients ◽  
Significant Difference ◽  
Quasi Experimental ◽  
The Brain

Stroke becomes a significant problem for developing countries. In Indonesia the data show its incidences 234 per 100.000 people, and around 2 - 8 % stroke patients experiencing cerebrovascular session will get neurophaty pain. It happens because of sensoric deviation after stroke, so the brain does not completely send information to the body correctly. Patients experiencing neurophaty pain are able to face decreasing living quality as the effect of long term painful disturbance. Therefore, it is important to maintain the patients’ living quality. The aim of the study is to investigate the comparison of using gabapentin and amitriptilin toward living quality of ischemic stroke patients with neurophaty pain in the hospitals in Jogja. The method used in this study was quasi experimental with consequtive sampling. The study was conducted on 22nd of April-31st of Juli 2013 by involving 23 patients in gabapentin group and 18 patientsin amitriptilin group that would be evaluated during 1 month. Living quality was assessed by Brief Pain Inventory (BPI) in week 0 and week 4. The result of the study showed that the use of gabapentin and amitriptilin in 4 weeks showed the increase of living quality represented by decreasing the score based on BPI questioner 1.67±0.78 and 1.37±0.80 with p-value>0.05 meaning that there was no significant difference. It can be concluded the comparison of using gabapentin and amitriptilin in post ischemic stroke patient with neuropathy pain not significantly increase the quality of in the hospitals in Jogja.

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