Kismet-dependent regulation of glutamate receptor clustering and synaptic transmission at the Drosophila neuromuscular junction

2021 ◽  
Author(s):  
Rupa Ghosh
Keyword(s):  
Neuromuscular Junction ◽  
Synaptic Transmission ◽  
Glutamate Receptor ◽  
Receptor Clustering

scholarly journals Glial Wingless/Wnt Regulates Glutamate Receptor Clustering and Synaptic Physiology at the Drosophila Neuromuscular Junction

2014 ◽  
Vol 34 (8) ◽  
pp. 2910-2920 ◽  
Author(s):  
K. S. Kerr ◽  
Y. Fuentes-Medel ◽  
C. Brewer ◽  
R. Barria ◽  
J. Ashley ◽  
...  
Keyword(s):  
Neuromuscular Junction ◽  
Glutamate Receptor ◽  
Receptor Clustering ◽  
Synaptic Physiology

scholarly journals Kismet Positively Regulates Glutamate Receptor Localization and Synaptic Transmission at the Drosophila Neuromuscular Junction

PLoS ONE ◽  
2014 ◽  
Vol 9 (11) ◽  
pp. e113494 ◽  
Author(s):  
Rupa Ghosh ◽  
Srikar Vegesna ◽  
Ramia Safi ◽  
Hong Bao ◽  
Bing Zhang ◽  
...  
Keyword(s):  
Neuromuscular Junction ◽  
Synaptic Transmission ◽  
Glutamate Receptor ◽  
Receptor Localization

scholarly journals Lola regulates glutamate receptor expression at the Drosophila neuromuscular junction

Biology Open ◽  
2012 ◽  
Vol 1 (4) ◽  
pp. 362-375 ◽  
Author(s):  
A. Fukui ◽  
M. Inaki ◽  
G. Tonoe ◽  
H. Hamatani ◽  
M. Homma ◽  
...  
Keyword(s):  
Neuromuscular Junction ◽  
Glutamate Receptor ◽  
Receptor Expression

Long-term facilitation alters transmitter releasing properties at the crayfish neuromuscular junction

1986 ◽  
Vol 55 (3) ◽  
pp. 484-498 ◽  
Author(s):  
J. M. Wojtowicz ◽  
H. L. Atwood
Keyword(s):  
Neuromuscular Junction ◽  
Synaptic Transmission ◽  
Time Course ◽  
Muscle Fibers ◽  
Low Frequencies ◽  
Before And After ◽  
Binomial Parameter ◽  
Small Muscle ◽  
Long Term Facilitation

Synaptic transmission at the neuromuscular junction of the excitatory axon supplying the crayfish opener muscle was examined before and after induction of long-term facilitation (LTF) by a 10-min period of stimulation at 20 Hz. Induction of LTF led to a period of enhanced synaptic transmission, which often persisted for many hours. The enhancement was entirely presynaptic in origin, since quantal unit size and time course were not altered, and quantal content of transmission (m) was increased. LTF was not associated with any persistent changes in action potential or presynaptic membrane potential recorded in the terminal region of the excitatory axon. The small muscle fibers of the walking-leg opener muscle were almost isopotential, and all quantal events could be recorded with an intracellular microelectrode. In addition, at low frequencies of stimulation, m was small. Thus it was possible to apply a binomial model of transmitter release to events recorded from individual muscle fibers and to calculate values for n (number of responding units involved in transmission) and p (probability of transmission for the population of responding units) before and after LTF. In the majority of preparations analyzed (6/10), amplitude histograms of evoked synaptic potentials could be described by a binomial distribution with a small n and moderately high p. LTF produced a significant increase in n, while p was slightly reduced. The results can be explained by a model in which the binomial parameter n represents the number of active synapses and parameter p the mean probability of release at a synapse. Provided that a pool of initially inactive synapses exists, one can postulate that LTF involves recruitment of synapses to the active state.

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