scholarly journals Rhinoorbital mucormycosis in COVID-19 pandemic: presentation and course of disease: An observational study

2022 ◽  
Vol 7 (4) ◽  
pp. 624-629
Author(s):  
Maya Sharma ◽  
Seema Rajvanshi ◽  
Sunita Khurana ◽  
Rajkumar Arora
Keyword(s):  
Blood Sugar ◽  
Rural Areas ◽  
District Hospital ◽  
Sudden Increase ◽  
Rt Pcr ◽  
Referral Centre ◽  
Course Of Disease ◽  
High Blood Sugar ◽  
Initial Symptoms ◽  
Key Factor

During the second wave of covid 19[SARS- Co V-] pandemic, there is a sudden increase in number of mucormycosis infection cases in India. The present study is an attempt to understand the presentation, course and outcome of rhinoorbital mucormycosis in a group of patients who reported to Ophtalmology and Otorhinolaryngology department of our Govt. District Hospital (secondary referral centre) for enhancing measures for prevention and management. Patients who reported to our Government district hospital with signs or symptoms suggestive of rhino orbital mucormycosis during May-June 2021 were included in the study with consent of ethical committee, patients and patient’s relatives. Total 17 cases were reported and followed. Clinical examination was done for all the patients. History of the presenting complaints and underlying illness with COVID -19 was elicited. Underlying comorbid status was recorded. Patients were followed as all of them were referred to higher centre for further management as per the guidelines issued by directorate medical and health services, rajasthan, Jaipur.13(76.4%) patients were from rural and 4 (23.5%) were from urban area. 11(64.7%) patients had RT-PCR +ve, 6 had RT-PCR _ve, 2 did not have RT-PCR report. 15(88.7%) patients had high blood sugar at presentation mean being 315.7mg%. 9 (52.9%) developed mucormycosis during their treatment for COVID in hospital. 8(47.05%) presented in OPD. 9 patients had treatment with inhalational Owhile 8 patients did not have treatment with O Death rate was high (70.5%) among our patients. Patients who survived (29.4%) had only initial symptoms and signs at presentation therefore could be managed earlier. None of our patient had vaccination for COVID. Our study was done at secondary referral centre, all the previous studies were done at tertiary referral centres; therefore it shows the course of disease mainly among rural population ; most of them presented very late and had poor outcomes. It shows the need of more awareness about COVID and mucormycosis among people especially in rural areas. High blood sugar either due to treatment with steroids or pre existing is a major risk factor for Rhino orbital mucormycosis. Being RT- PCR negative for COVID 19 does not rule out the associated possible complication of Rhino orbital mucormycosis. Early diagnosis and management remains the key factor for managing Rhino orbital mucormycosis.

Entrepreneurship, Broadband, and Gender: Evidence from Establishment Births in Rural America

2021 ◽  
pp. 016001762110187
Author(s):  
Tessa Conroy ◽  
Sarah A. Low
Keyword(s):  
Rural Areas ◽  
Small Businesses ◽  
Birth Rate ◽  
Broadband Access ◽  
Rural America ◽  
Variable Approach ◽  
Key Factor ◽  
Business Size ◽  
And Gender ◽  
Instrumental Variable Approach

Broadband access may have important implications for establishment births in rural areas, which feature thinner markets. Broadband may be especially important for rural nonemployer businesses, particularly those without a storefront, for access to nontraditional market channels. As women are more likely to run these types of small businesses, we further expect that broadband may have important implications for women-led businesses. With an effective instrumental variable approach, we find evidence that broadband access is a key factor leading to a higher establishment birth rate across business size and gender in rural areas. This paper identifies the largest effects on nonemployer, women-led and remote rural establishments.

scholarly journals THE HYPOPHYSIS AND SECRETION OF INSULIN

1942 ◽  
Vol 75 (5) ◽  
pp. 547-566 ◽  
Author(s):  
B. A. Houssay ◽  
V. G. Foglia ◽  
F. S. Smyth ◽  
C. T. Rietti ◽  
A. B. Houssay
Keyword(s):  
Insulin Secretion ◽  
B Cells ◽  
Blood Sugar ◽  
Anterior Pituitary ◽  
Blood Sugar Level ◽  
Pituitary Hormone ◽  
Pituitary Extract ◽  
Histological Changes ◽  
High Blood Sugar ◽  
Anterior Pituitary Hormone

The ability of the pancreas, from various types of dogs, to correct diabetic hyperglycemia has been studied (Table XI). The pancreas from one animal was united by a vascular union with the neck blood vessels of another dog which had been pancreatectomized for 20 hours. The time necessary to reduce the blood sugar level to 120 mg. per cent was determined. 1. Pancreas from 6 hypophysectomized dogs produced a normal insulin secretion, showing that an anterior pituitary hormone is not necessary for its production or maintenance. 2. In 14 of 17 normal dogs given anterior pituitary extract for 3 or more consecutive days and presenting diabetes (fasting blood sugar 150 mg. per cent or more) the pancreas showed diminished insulin production. 3. In animals which remained diabetic after discontinuing the injections of hypophyseal extract, the pancreas islands were markedly pathologic and the insulin secretion was practically nil. 4. When hyperglycemia existed on the 2nd to 5th day but fell later, the insulin secretion of 5 dogs was normal in 2, supernormal in 1, and less than normal in 2. Histologic examination showed a restoration of beta cells. 5. In 14 dogs resistant to the diabetogenic action of anterior pituitary extract, as shown by little or no change in blood sugar, the pancreatic secretion of insulin was normal in 6 cases, supernormal in 3, and subnormal in 5 cases. Clear signs of hyperfunction of B cells were observed. In 6 resistant animals a high blood sugar (150 mg. per cent) appeared shortly before transplanting, but insulin secretion was normal in 4, supernormal in 1, and subnormal in 1 case. 6. With one injection of extract and 1 day of hyperglycemia the capacity of the pancreas to secrete insulin was not altered. 7. A high blood sugar level lasting 4 days does not alter the islets. The hypophyseal extract acts, therefore, by some other mechanism. In normal dogs, the continuous intravenous infusion of glucose for 4 days maintained the blood sugar at levels as high as those after pituitary extract. In these animals the B cells were hyperplastic and insulin secretion normal. 8. Anterior hypophyseal hyperglycemia is due at first to extrapancreatic factors which are the most important, and last only during the injections of extracts. Pancreatic factors appear afterwards and are responsible for permanent diabetes. Hypophyseal extract produces histological changes in many tissues and damages the Langerhans islands. The coexistent high blood sugar probably exhausts the B cells and exaggerates their injury. 9. In all cases there is a relation between the cytology of the islet B cells and the insulin secreting capacity.

scholarly journals A MODERN OVERVIEW ON DIABETES MELLITUS: A CHRONIC ENDOCRINE DISORDER

2020 ◽  
Vol 5 (2) ◽  
pp. 1-14
Author(s):  
Y Mukhtar ◽  
A Galalain ◽  
U Yunusa
Keyword(s):  
Diabetes Mellitus ◽  
Blood Sugar ◽  
Insulin Dependent Diabetes Mellitus ◽  
Insulin Dependent Diabetes ◽  
Hypoglycemic Agents ◽  
Dependent Diabetes Mellitus ◽  
High Blood Sugar ◽  
Type 2 Dm ◽  
Insulin Dependent

Diabetes mellitus is one of the most common endocrine disorders that affect the body’s ability to make or use insulin. Diabetes mellitus (DM), or simply diabetes, is a group of chronic metabolic diseases in which a person experience high blood sugar, either because the pancreas does not produce enough insulin or because the body cells do not effectively use or respond to the insulin that is produced. This high blood sugar produces the classical symptoms of polyuria (frequent urination), polydipsia (increased thirst) and polyphagia (increased hunger). Conventionally, diabetes has been divided into three types namely: Type 1 DM or insulin-dependent diabetes mellitus (IDDM) in which body fails to produce insulin, and presently requires the person to inject insulin or wear an insulin pump. This is also termed as "juvenile diabetes". Type 2 DM or non-insulin-dependent diabetes mellitus (NIDDM), results from insulin resistance, a condition in which cells fail to use insulin properly, with or without an absolute insulin deficiency. This type was previously referred to as or "adult-onset diabetes". The third main type is gestational diabetes which occurs when women without a previous history of diabetes develop a high blood glucose level during her pregnancy and may metamorphose to type 2 DM after giving birth. Currently available pharmacotherapy for the treatment of diabetes mellitus includes insulin and oral hypoglycemic agents. Thus, the present review underscores the issues surrounding the symptoms, diagnosis and treatment (especially use of anti-diabetic herbal species) of this killer disease with a view to suppressing its global spread and resurgence.

scholarly journals Fasdhu therapy to reduce excess levels of substances in the human body

2021 ◽  
Vol 6 (7) ◽  
pp. 1276-1281
Author(s):  
Darmadi Darmadi ◽  
Siti Juariah ◽  
Sukri Sukri
Keyword(s):  
Uric Acid ◽  
Health Education ◽  
Blood Sugar ◽  
Body Fat ◽  
Human Body ◽  
High Blood Sugar ◽  
The People ◽  
Sugar Levels ◽  
Provide Health Education

Tarai Bangun Hamlet IV, Tarab Mulya Village is a village located in Kampar Regency where the majority of the people come from the Minang and Javanese tribes. They like to eat fatty foods that trigger an increase in body fat levels. This service is carried out with the aim of helping people who experience high blood sugar, cholesterol and uric acid levels with the phlebotomy technique (fasdhu). The method used is to provide health education, followed by checking blood sugar, cholesterol and uric acid. High levels are then performed Fasdhu. Based on the examination of blood sugar, cholesterol and uric acid checks on 37 respondents, it was found that 10 respondents had high levels. Fasdhu treatment was carried out on respondents who had blood sugar levels of 163 mg/dl, cholesterol 240.75 mg/dl and uric acid 8.95 mg/dl. After fasdhu treatment, the levels decreased to 107 mg/dl, 200 mg/dl and 7.15 mg/dl, respectively. Based on this treatment, it was concluded that the phlebotomy technique (fasdhu) could be recommended as an effort to reduce blood sugar, cholesterol and uric acid levels.

Stressful life events, hypertensive disorders, and high blood sugar during pregnancy

2020 ◽  
Vol 36 (2) ◽  
pp. 160-165
Author(s):  
Liwei Chen ◽  
Lu Shi ◽  
Margaret Shin Chao ◽  
Xia Tong ◽  
Fan Wang
Keyword(s):  
Blood Sugar ◽  
Life Events ◽  
Stressful Life Events ◽  
Stressful Life ◽  
High Blood Sugar ◽  
Hypertensive Disorders

High Blood Sugar Levels in Rhesus Monkeys

1967 ◽  
Vol 46 (5) ◽  
pp. 1105-1105 ◽  
Author(s):  
Harold P. Rose ◽  
James S. Glenn ◽  
Andrew Kuna
Keyword(s):  
Blood Sugar ◽  
Rhesus Monkeys ◽  
High Blood Sugar ◽  
Sugar Levels

Integrated Assessment: A Rural Model in Practice

2001 ◽  
Vol 7 (1) ◽  
pp. 106 ◽  
Author(s):  
Leona J. Mann
Keyword(s):  
Rural Areas ◽  
Integrated Assessment ◽  
Rural Setting ◽  
The Past ◽  
Innovative Process ◽  
Key Factor

Integrated assessment in Victoria, Australia is held to be a new and innovative process, but in Gippsland, Victoria, integrated assessment has been a reality for the past four years. The purpose of this paper is to identify the elements of integrated assessment in a rural setting. The research has found that identifying the components of such a model was a key factor in achieving the ideals of integrated assessment. The paper suggests that integrated assessment may be more easily achieved in rural areas than its metropolitan counterparts.

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