scholarly journals Glaucoma characteristics evaluation in myopia – A clinical study

2021 ◽  
Vol 7 (2) ◽  
pp. 195-199
Author(s):  
Helen Rosita J ◽  
Gnanaselvan J ◽  
Amudhavadivu S ◽  
Anna Kurian Mullasseril
Keyword(s):  
Optic Nerve ◽  
Optic Nerve Head ◽  
High Myopia ◽  
Intra Ocular Pressure ◽  
Significant Difference ◽  
Long Term Follow Up ◽  
Ocular Pressure ◽  
The Mean ◽  
One Year ◽  
High Degree

Glaucoma is the leading cause of irreversible blindness, one of the risk factor recognised being high myopia. Intra ocular pressure may be normal in myopic patients, with optic nerve head glaucoma characteristics. Eye ball elongation and optic nerve head tilting may be present in patients with high myopia that will represent field defects mimicking glaucoma. Treating patients with myopia having suspected aspects of glaucoma may be a challenge but even more challenging is the diagnosis of glaucoma in myopic patients.: To evaluate the association of glaucoma features with myopia. To create the awareness regarding the long term follow up.: Patients in the age group of 15 to 45 years who had attended our institution over a period of one year who fulfilled the inclusion and exclusion criteria were subjected for this study. Fifty four patients who were diagnosed to have moderate or high degree myopia were selected for this analytical study. They were subjected to vision, ocular examination, tonometry and results obtained were analysed.: In our study moderate myopes constituted 55.5% and high myopes were 44.5%. The mean Intra ocular pressure and the mean corrected Intra ocular pressure in high myopes were observed to be higher than in moderate myopia. It was observed that higher prevalence of glaucoma was observed in high myopes.: There is a clinically as well as statistically significant difference between mean Intra ocular pressure and mean corrected Intra ocular pressure. So mean corrected Intra ocular pressure should be measured .From our study, there is a clear indication that there is increased prevalence of glaucoma in high myopes.

scholarly journals Referral parameters for diagnosis of glaucoma in general eye clinic at Tilganga Institute of Ophthalmology

2019 ◽  
Vol 11 (1) ◽  
pp. 33-39
Author(s):  
Pratibha Lama Joshi ◽  
Bhaskar Jha ◽  
Indira Paudyal ◽  
Suman Shamsher Thapa
Keyword(s):  
Optic Nerve ◽  
Optic Nerve Head ◽  
Open Angle Glaucoma ◽  
Corneal Thickness ◽  
Normal Group ◽  
Intra Ocular Pressure ◽  
Glaucoma Diagnosis ◽  
Ocular Pressure ◽  
The Mean ◽  
Eye Clinic

Objective: To find out the most common referral parameter among the glaucoma suspects patients from general eye clinic and to establish glaucoma diagnosis. Methods: This study is a retrospective cohort hospital based study. Two hundred patients from January to February 2017 sent to glaucoma clinic as glaucoma suspects were re-evaluated meticulously by glaucoma specialist and were diagnosed as glaucoma, non glaucoma, suspects and ocular hypertension. Results: Out of the 200 patients referred to glaucoma clinic as glaucoma suspects only19% were diagnosed to have glaucoma. The mean age at which glaucoma diagnosed was 55.29(14.4) compared to 41.6(15.1) in normal group. One hundred and sixty five patients were referred on the basis of suspicious optic nerve head, among them 14.5% (24/165) had glaucoma. This study showed that, open angle glaucoma (OAG) 28.9% was the most common type of total glaucoma diagnosed. The mean vertical cup discratio in the OAG group was 0.69±0.1 (0.4 -0.9) compared to 0.56 ± 0.11((0.2-0.8)(p=0.00) normal. The mean intra ocular pressure (IOP) in OAG group was 19.73 ±4.95(11-32) mmHg compared to 16.74± 3.36(10-30) mmHg (p=0.00) in normal group. The mean central corneal thickness (CCT) in OAG group was 533.05 ± 31.24μm (467-606) compared to normal was 534.9±33.6 μm (432-696) (p=0.670). Conclusions: Suspicious optic nerve head is the most common referral parameter between the general ophthalmologist and residents, but this study shows only few of them were diagnosed with glaucoma. This gives us a clue that the ophthalmologists and residents are to be trained better to help them identify the signs of glaucoma on the optic nerve head beside its size, which will reduce unnecessary burden to the resources of patients and hospital.

Outcomes of conbercept therapy for choroidal neovascularization secondary to pathological myopia

2021 ◽  
Vol 2 (4) ◽  
pp. 210-213
Author(s):  
Zheng-Feng Liu ◽  
◽  
Da-Dong Guo ◽  
Mei-Hua Ding ◽  
Hong-Sheng Bi ◽  
...  
Keyword(s):  
Choroidal Neovascularization ◽  
Fundus Fluorescein Angiography ◽  
Pathological Myopia ◽  
Foveal Thickness ◽  
Central Foveal Thickness ◽  
Significant Difference ◽  
Long Term Follow Up ◽  
The Mean ◽  
One Year

AIM: To evaluate the one-year outcome of intravitreal conbercept injections for the treatment of choroidal neovascularization secondary to pathological myopia (pm-CNV) by optical coherence tomography angiography (OCTA). METHODS: The medical records of 26 consecutive eyes of 23 patients who received intravitreal injections of conbercept for pm-CNV with a follow-up of one year were retrospectively reviewed. All the patients were diagnosed by fundus fluorescein angiography (FFA) and OCTA at the first visit. All approaches were performed as “1+PRN” treatment. Outcomes included best-corrected visual acuity (BCVA), central foveal thickness (CFT) and the mean CNV area by OCTA. RESULTS: Mean Logarithm BCVA improved from (0.66±0.51) at baseline to (0.39±0.38) at one year (t=3.528, P=0.004). The CFT before treatment and after one year after were 275.08±48.74) μm and (205.15±43.74) μm respectively (t=4.630, P=0.001). The mean pm-CNV areas before treatment and after one year treatment were (0.48±0.24) mm2 and (0.15±0.11) mm2 respectively, with a significant difference among them (t=5.329, P=0.000). Twenty-one eyes had no needs after the first treatment. Four eyes received 2 injections and only one eye received 3 injections. No severe adverse events were noted relevant to the therapy. CONCLUSION: Intravitreal conbercept can improve the vision and relieve CFT and CNV area for the treatment of pm-CNV with “1+PRN” by OCTA for one year, however, long-term follow-up still need to be performed.

Early Post-Operative Effect of Phacoemulsification on Anterior Chamber Depth and Intraocular Pressure in Patients with Cataract

2021 ◽  
Vol 37 (2) ◽  
Author(s):  
Mashal Tayyab ◽  
Awaid Abid
Keyword(s):  
Intraocular Pressure ◽  
Anterior Chamber ◽  
Anterior Chamber Depth ◽  
Pressure Change ◽  
P Value ◽  
Iol Implantation ◽  
Intra Ocular Pressure ◽  
Significant Difference ◽  
Ocular Pressure ◽  
The Mean

Purpose:  To determine the Anterior Chamber depth and Intraocular pressure change following uncomplicated phacoemulsification. Study Design:  Quasi experimental study. Place and Duration of Study:  Layyton Rehmatullah Benevolent Trust Free Eye and Cancer Hospital, Lahore from 16/12/2017 to 15/06/2018. Methods:  One hundred and thirty nine patients who came to Layyton Rehmatullah Benevolent Trust Free Eye for phacoemulsification and IOL implantation were included in the study. Anterior Chamber depth was measured with IOL Master and intraocular pressure was determined using Goldmann Applanation Tonometer one day before and one month after surgery. Data was recorded on a self-designed proforma. Comparison between pre- and post-operative data with respect to change was analyzed by chi-square test. P-value ≤ 0.05 was considered significant. Results:  The mean intra-ocular pressure dropped from 14.36 ± 4.19 mmHg to 12.14 ± 4.26 mmHg 1 month after surgery with a mean drop of 2.21 ± 0.65 mmHg while the mean anterior chamber depth increased from 2.31 ± 0.08 mm to 3.59 ± 0.37 mm with a mean increase of 1.29 ± 0.36 mm. There was no statistically significant difference in the mean change of intra-ocular pressure and anterior chamber depth across various subgroups based on patient’s age, gender and duration of cataract. Conclusion:  Phacoemulsification and IOL implantation not only improves the visual acuity by removing the cataract but also deepens the anterior chamber and decreases intra-ocular pressure, which can have a beneficial effect in glaucoma patients. Key Words:  Phacoemulsification, Cataract, Intraocular pressure, Lens, Anterior chamber depth.

scholarly journals Non-contact Tonometry Versus Pachymetry Corrected Intraocular Pressure: Any Difference? A Case for Pachymetry during Glaucoma Screening

2019 ◽  
pp. 1-7
Author(s):  
E. Awoyesuku ◽  
A. A. Onua
Keyword(s):  
Intraocular Pressure ◽  
Pressure Measurement ◽  
Corneal Thickness ◽  
Intra Ocular Pressure ◽  
Glaucoma Screening ◽  
Port Harcourt ◽  
Department Of Ophthalmology ◽  
Significant Difference ◽  
Ocular Pressure ◽  
The Mean

Objective: This study sets out to determine if there is any statistical difference in the results of measuring intraocular pressure (IOP) uncorrected for Central Corneal Thickness with Air Puff Tonometry and corrected with pachymetry for clients undergoing screening for glaucoma at the department of Ophthalmology, University of Port Harcourt Teaching Hospital (UPTH), Nigeria. Methods: One hundred and thirty-two (132) adults were screened for glaucoma during the 2019 World Glaucoma week in UPTH Port Harcourt, they had their IOPs measured with Air Puff (Non-contact) Tonometer (Pulsair intelliPuff Tonometer, Keeler), after which they underwent pachymetry (Sonomed Escalon PacScan Plus) to determine corneal thickness after which the corrected IOP was determined by using a correction factor for adjusting IOP based on corneal thickness [1].  The results were analyzed using SPSS version 20 to determine statistical differences. Results: There was a statistically significant difference between intraocular pressure (IOP) measurements when corrected with pachymetry than when it is uncorrected. In our study the mean uncorrected IOP RE and LE was 14.53 mmHg and14.75 mmHg respectively while Corrected IOP RE and LE was 16.37 mmHg and 16.72 mmHg respectively. Conclusion: Intra ocular pressure measurement adjusted with pachymetry for corneal thickness may be a better option for tonometry and we propose this be considered during intra ocular pressure measurement.

scholarly journals Optic Nerve Head Elasticity and Corneal Biomechanics in Patients with Optical Disc Drusen and Optic Disc Edema

2021 ◽  
Author(s):  
Ozge SARAC ◽  
Yelda Y TASCI ◽  
Nilufer YESILIRMAK ◽  
Ozlem UNAL ◽  
Semih ONER ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Optic Disc ◽  
Optic Nerve Head ◽  
Corneal Biomechanics ◽  
Optic Disc Edema ◽  
Disc Edema ◽  
Significant Difference ◽  
The Mean ◽  
Group 2 ◽  
Group 1

Abstract Purpose: The purpose of the study is to evaluate the efficacy of ultrasound elastography (USE) in differentiating optic disc drusen (ODD) from optic disc edema (ODE) and to investigate the relationship between corneal biomechanics and optic nerve elasticity. Methods: This prospective, clinical study included 28 eyes of 16 ODD patients (Group 1), 23 eyes of 18 ODE patients (Group 2) and 30 eyes of 15 healthy controls (Group 3). Best corrected distance visual acuity (BDVA), corneal hysteresis (CH), corneal resistance factor (CRF), corneal-compensated intraocular pressure (IOPcc), Goldmann-correlated IOP (IOPg) and optic nerve head (ONH)-elasticity were measured. Results: The mean BDVA value was significantly lower in Group 2 compared to Groups 1 and 3 (p<0.001), there was no significant difference between Groups 1 and 3 (p=0.089). The mean intraconal fat to ONH ratio was significantly higher in Group 1 compared to Group 2 (p=0.008) and 3 (p=0.002), there was no significant difference between Group 2 and 3 (p=0.182). The receiver operating characteristic curve areas for ONH-elasticity in differentiating group 1 and group 2 was 0.728 (p=0.008) with 80% sensitivity and 60% specificity when the cut-off point was set at 2.29. Corneal biomechanics (CH, CRF, IOPcc, IOPg) were not different between the three groups (p>0.05), however there was a significant correlation between corneal and ONH biomechanics in drusen group (p<0.05). Conclusion: The evaluation of the ONH with USE seems to provide useful data in differentiating ODD from ODE. Significant correlation was revealed between corneal and ONH biomechanics in drusen group.

scholarly journals Thermoregulation in colonies of africanized and hybrids with Caucasian, Italian and Carniolan Apis mellifera honey bees

1999 ◽  
Vol 42 (4) ◽  
Author(s):  
Vagner de Alencar Arnaut de Toledo ◽  
Regina Helena Nogueira-Couto
Keyword(s):  
Apis Mellifera ◽  
Honey Bees ◽  
Maximum Temperature ◽  
Tropical Region ◽  
Internal Temperature ◽  
Africanized Honey Bees ◽  
Significant Difference ◽  
The Mean ◽  
One Year ◽  
Brood Nest

This experiment was carried out to study the internal temperature regulation of a colony of Africanized honey bees (AFR), compared with hybrid Caucasian (CAU), Italian (ITA), and Carniolan (CAR) bees, during the period of one year and different size hives located in a sub-tropical region. The instant internal temperature, 33.7 ± 1.5° C for the AFR, 33.5 ± 1.4° C for the CAU, 33.7 ± 1.5° C for the ITA and 33.8 ± 1.4° C for the CAR, did not show any significant difference (P>0.05). The maximum temperature (36.1 ± 2.3° C) was statistically different (P<0.05) from the minimum (27.6 ± 5.3° C). There was no difference (P>0.05) in the mean internal temperature, between the nucleus (31.7 ± 6.3° C) and the brood nest (32.1 ± 5.3° C) measured between two and four o'clock in the afternoon.

scholarly journals TOLAK UKUR FUNGSI HATI BERDASARKAN DERAJAT FIBROSIS PENYAKIT HATI KRONIS (Liver Function Parameters based on Degree of Liver Fibrosis in Chronic Liver Disease)

2018 ◽  
Vol 21 (1) ◽  
pp. 57
Author(s):  
Rahmafitria Rahmafitria ◽  
Mutmainnah Mutmainnah ◽  
Ibrahim Abdul Samad
Keyword(s):  
Liver Disease ◽  
Liver Fibrosis ◽  
Liver Function ◽  
Chronic Liver Disease ◽  
Total Bilirubin ◽  
Chronic Liver ◽  
Low Degree ◽  
Significant Difference ◽  
The Mean ◽  
High Degree

Evaluating the degree of liver fibrosis degree is invasive as well as uncomfortable, therefore, non invasive examinations such as liverfunction tests and elastography (Fibro Scan) as a predictor‘s device of liver fibrosis degree are necessary. The aim of this study was toknow the differences of liver function parameters based on the fibrosis degree in patients with chronic liver disease. This study was a crosssectional design using data from chronic liver disease patients treated at the Dr. Wahidin Sudirohusodo Hospital. The elasticity of the liverwas measured using a fibro scan device during June 2010–July 2011. The analysis was carried out by ANOVA test on various parametersof liver function particularly on the fibrosis degree in chronic liver disease. In this study PT, albumin, total bilirubin and platelet countshowed a significant difference of 0.019, 0.009, 0.017 and 0.000 respectively. The mean values of PT and total bilirubin were significantlyhigher in the high degree of fibrosis compared to those with medium and low degree of fibrosis in the chronic liver disease patients. Basedon this study, the mean albumin levels and platelet count were significantly lower in the high degree of fibrosis compared with the mediumand low degree of fibrosis, however, no significant differences in AST, ALT, APTT and GGT were found.

scholarly journals PETER’S ANOMALY

2013 ◽  
Vol 3 (1) ◽  
Author(s):  
Laya Rares
Keyword(s):  
Penetrating Keratoplasty ◽  
Corneal Opacity ◽  
Health Condition ◽  
Pressure Management ◽  
Filtration Surgery ◽  
Intra Ocular Pressure ◽  
Ocular Pressure ◽  
One Year ◽  
The Right ◽  
Peter’S Anomaly

Abstract: Peter’s anomaly is a congenital corneal anomaly characterized by central or paracentral opacity. Around 60-80% of this anomaly is bilateral. We reported a girl of one year and six months as having bilateral corneal opacity since she was born. Diagnosis was based on ophthalmological examinations: the vision of the right and left eyes was ‘fix and follow the light’; sensoric nystagmus of both eyes; intra-ocular pressure of the right eye 37 mm Hg and of the left eye 40 mm Hg; corneal diameters of both eyes were 11 mm; 5-mm-central opacity of both cornea; both eye movements to all directions were normal; anterior chambers were shallow; iris was attached to the corneal endothelium; both lenses were difficult to be evaluated due to corneal opacity; fundal reflexes in both eyes were negative. The early medication given was thymolol 0.5% to decrease the intra-ocular pressure. If her health condition improved, a penetrating keratoplasty and a filtration surgery were recommended under general anaesthesia. Key words: Peter’s anomaly, corneal opacity, intraocular pressure, management.   Abstrak: Peter’s anomaly merupakan kelainan kongenital kornea yang ditandai dengan kekeruhan pada kornea bagian sentral ataupun parasentral. Sekitar 60-80% kasus Peter’s anomaly terjadi bilateral. Kami melaporkan kasus Peter’s Anomaly pada seorang anak berusia satu tahun enam bulan dengan kekeruhan pada kedua mata sejak lahir. Diagnosis ditegakkan berdasarkan pemeriksaan oftalmologis dimana didapatkan visus okuli dekstra dan sinistra fix and follow the light, nistagmus sensoris pada kedua mata, tekanan intra okuler pada mata kanan 37 mm Hg dan pada mata kiri 40 mmHg. Diameter kornea kedua mata 11 mm, adanya  kekeruhan pada sentral kornea (stroma) dengan diameter 5 mm pada kedua mata. Pergerakan  kedua mata ke semua arah normal. Bilik mata anterior dangkal, iris melekat pada endotel kornea, lensa kedua mata sukar dievaluasi oleh karena kekeruhan pada kornea. Refleks fundus negatif pada kedua mata. Penanganan awal yang diberikan berupa medikamentosa (timolol 0,5%) untuk menurunkan tekanan intra okuler sambil menunggu keadaan umum membaik untuk dilakukan penetrating keratoplasty and filtration surgery dibawah anastesi umum. Kata Kunci: Peter’s anomaly, kekeruhan kornea, tekanan intra okuler, penanganan.

scholarly journals Morphology and Microcirculation Changes of Optic Nerve Head Between Simple High Myopia and Pathologic Myopia

2021 ◽  
Author(s):  
Wenquan Tang ◽  
Xuanchu Duan ◽  
Junyi Ouyang ◽  
YuLin Luo ◽  
Xilang Wang
Keyword(s):  
Optic Nerve ◽  
Optic Nerve Head ◽  
High Myopia ◽  
Structural Changes ◽  
Pathologic Myopia ◽  
Disease Development ◽  
Pathological Changes ◽  
Choroidal Perfusion ◽  
Morphology Changes

Abstract This study explored morphology and microcirculation changes of optic nerve head (ONH) in simple high myopia(SHM) and pathologic myopia(PM), in order to evaluate and identify ONH changes in the development of PM. We divided 193 right eyes of 193 patients into SHM and PM according to the retinopathy. We found that ONH is one of the earliest pathological changes in myopia, and its morphology changes were also the most obvious. PM is closely linked to the reduction of choroidal perfusion and structural changes of ONH. Microcirculation showed a significant priority changes in myopia. Further research should address whether these fndings are associated with future disease development in highly myopic eyes.

scholarly journals Gender differences in the influence of obstructive sleep apnea on optic nerve head circulation

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Tomoaki Shiba ◽  
Mao Takahashi ◽  
Tadashi Matsumoto ◽  
Yuichi Hori
Keyword(s):  
Gender Differences ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Optic Nerve ◽  
Optic Nerve Head ◽  
Laser Speckle ◽  
Laser Speckle Flowgraphy ◽  
Apnea Hypopnea Index ◽  
Obstructive Sleep ◽  
The Mean

AbstractWe investigated gender differences in the optic nerve head (ONH) microcirculation status in association with obstructive sleep apnea (OSA) by using laser speckle flowgraphy (LSFG). We evaluated 150 men (60.5 ± 11.0 yrs) and 45 women (63.0 ± 10.6 yrs) who underwent overnight polysomnography. The mean blur rate (MBR), maximum (Max) MBR, and minimum (Min) MBR were evaluated. The parameters were analyzed separately for the tissues, vessels, and throughout the ONH (All). The apnea hypopnea index (AHI: times/hr), the lowest SpO2%, and the mean SpO2% were calculated as indicators of OSA. We investigated which MBR sections are correlated with OSA parameters separately in the men and women. All MBR sections in the women were significantly positively correlated with the lowest SpO2. In the men, no MBR section was correlated with any OSA parameters. The factors contributing independently to MBR-Tissue were height (β = 0.31) and lowest SpO2 (β = 0.30). The lowest SpO2 in the women was significantly positively correlated with Max MBR-Tissue, Max MBR-All, and Min MBR-All. Our results confirmed a gender difference in characteristics of ONH microcirculation in association with OSA.

Sign in / Sign up

Export Citation Format

Share Document