scholarly journals Relationship Between Parafunctional Habits and Salivary Biomarkers

2020 ◽  
Author(s):  
Mina Khayamzadeh ◽  
Iraj Mirzaii-Dizgah ◽  
Pegah Aghababainejad ◽  
Sareh Habibzadeh ◽  
Mohammad Javad Kharazifard
Keyword(s):  
Salivary Cortisol ◽  
Control Group ◽  
Case Group ◽  
Depression Anxiety Stress Scale ◽  
Stress Biomarkers ◽  
Unstimulated Saliva ◽  
The Mean ◽  
Student’S T ◽  
As Stress ◽  
Student’S T Test

Objectives: Parafunctional habits, as one of the etiological factors of temporomandibular disorders (TMD), are an individual’s response to increased stress. During stress and depression, biomarkers such as cortisol and salivary alpha-amylase (SAA) are secreted in the saliva. The present study aimed to investigate whether there is a correlation between salivary stress biomarkers and parafunctional habits. Materials and Methods: Thirty-two cases, from May to September 2015, were selected based on two standard stress questionnaires, namely the depression anxiety stress Scale-21 (DASS-21) and the Beck Anxiety Inventory (BAI). Saliva samples were collected to examine the level of unstimulated salivary cortisol and SAA. The significance of the results was assessed via student’s t-test and Mann-Whitney test (α=0.05). Results: The mean concentrations of cortisol and SAA in unstimulated saliva were significantly higher in the case group than in the control group (P=0.01 and 0.44, respectively). The mean scores of anxiety, stress, and depression were significantly higher in the case group than in the control group (P<0.05). Conclusion: It seems that the levels of salivary cortisol and SAA, as well as stress, anxiety, and depression scores, are higher in patients with parafunctional habits.

scholarly journals ANALGESIC EFFICACY OF EPIDURAL MORPHINE AND CLONIDINEIN PATIENTS UNDERGOING DECOMPRESSION OF THE LUMBAR CANAL: A PROSPECTIVE RANDOMIZED TRIAL

2017 ◽  
Vol 16 (3) ◽  
pp. 188-192
Author(s):  
BRUNO RONCAGLIO ◽  
RAPHAEL FERNANDES CALHAU ◽  
CHARBEL JACOB JÚNIOR ◽  
IGOR MACHADO CARDOSO ◽  
JOSÉ LUCAS BATISTA JÚNIOR ◽  
...  
Keyword(s):  
Epidural Morphine ◽  
Randomized Study ◽  
Analgesic Efficacy ◽  
Control Group ◽  
Lumbar Arthrodesis ◽  
The Mean ◽  
Group 2 ◽  
Student’S T ◽  
Microsoft Office ◽  
Student’S T Test

ABSTRACT Objective: To evaluate the postoperative analgesic efficacy in patients undergoing lumbar canal decompression using epidural morphine and clonidine at the Hospital Santa Casa de Vitória - ES, Brazil. Methods: Prospective, randomized study of 60 patients with stenosis of the lumbar canal up to two levels with surgical indication, in which decompression of the canal was performed in association with lumbar arthrodesis. In group 1 we performed conventional postoperative analgesia and in group 2, in addition to conventional analgesia, we associated epidural morphine and clonidine. We used VAS as a means of analyzing pain intensity at 1, 12, and 36 hours after surgery. The statistical analysis was performed using Microsoft Office/Excel and the software GraphPad Prism (San Diego, CA, USA). Results: The mean age of patients was 47 years, and 52% were female. The mean VAS in the first hour, 12th, and 36th hours after surgery in the control group was 5.44, 2.13, and 0.55 respectively. In the morphine-clonidine group it was 6.96; 2.21 and 0.60. Comparing one group with another in its absolute values through the Mann-Whitney test, as well as comparing the pain variations between the 1st and 12th hour (1h X 12h) and between the 12th hour and 36th hour (12h x 36h ) through Student’s t test it became clear that there was no statistical difference between groups (p > 0.05). Conclusions: The addition of epidural morphine and clonidine to conventional analgesia is not beneficial to reduce postoperative pain in patients undergoing lumbar canal decompression.

Evaluation of Association between Perceived Stress, Anxiety, Depression, Salivary Alpha-Amylase and Salivary Cortisol with Chronic Periodontitis

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Fereidooni M ◽  
◽  
Nouri P ◽  
Faramarzi M ◽  
Sadeghi S ◽  
...  
Keyword(s):  
Salivary Cortisol ◽  
Chronic Periodontitis ◽  
Alpha Amylase ◽  
Anxiety And Depression ◽  
Control Group ◽  
Case Group ◽  
Depression And Anxiety ◽  
The Mean ◽  
The Difference ◽  
Mean Concentration

Introduction: Chronic Periodontitis is a multifactorial inflammatory disease, which is caused by certain series of bacteria in oral biofilm and leads to teeth supporting tissue destruction. Stress, depression and anxiety can affect periodontium health through variable different mechanisms. Cortisol is secreted from adrenocorticotropic glands in pituitary gland and can be used as index to determine psychological stress rate. Alpha-amylase is an salivary gland enzyme which is regulated through sympatric nervous system. The aim of the following study is to compare between different biomarkers related to the emotional stress, anxiety and depression in saliva and their role on periodontal health and also the correlation between periodontal parameters, stress, depression and anxiety. Method: 90 patients with age ranged from 35 to 45 years were participated in the study. Salivary cortisol and alpha-amylase levels were measured in them. Levels of Stress, Anxiety and Depresion were evaluated using questionnaires. The relationship between psychological and biochemical factors with chronic Periodontitis were assessed. The results were analyzed by statistical analysis. Results: The mean concentration of salivary cortisol was 7.87±4.37 ng/ml in the case group and 4.33±2.11 ng/ml in the control group. The difference was statistically significant (p<0.001). The mean concentration of salivary alphaamylase was 3569.27±101.22 U/L in the case group and 3343.44±171.09 U/L in the control group. The difference was statistically significant (p<0.001). The mean stress score was 24.28±3.09 in the case group and 22.96±3.61 in the control group. The difference between two groups was statistically significant (p<0.001). The difference between two groups was statistically significant (p<0.001). The mean anxiety score was 44.11±4.59 in the case group and 36.47±4.30 in the control group, which was statistically significant (p<0.001). The mean depression score was 19.96±3.58 in the case group and 13.13±3.91 in the control group. The difference between two groups was statistically significant (p<0.001). Conclusion: The findings of these study showed that psychological factors like emotional stress, depression and anxiety and biochemical factors including salivary cortisol and alpha-amylase are higher in patients with moderate to severe chronic periodontitis in comparison to healthy people. also Anxiety and depression are stronger predictors of periodontitis than acute stress and cortisol.

Condylar Asymmetry Measurements in Patients with Temporomandibular Disorders

2004 ◽  
Vol 5 (3) ◽  
pp. 59-65 ◽  
Author(s):  
Ali Alp Sağlam ◽  
Gülperi Şanli
Keyword(s):  
Temporomandibular Disorders ◽  
Asymmetry Index ◽  
T Test ◽  
Control Group ◽  
The Mean ◽  
Student’S T ◽  
The Relationship ◽  
Experimental Group ◽  
Student’S T Test

Abstract Objectives The relationship between condylar asymmetry and handedness of the patients with temporomandibular disorders (TMD) and patients with no signs or symptoms of TMD was investigated. The experimental group consisted of 25 patients aged 15 to 52 years who were referred for treatment of TMD. The mean age of this group was 26.24 years. The control group consisted of 25 patients aged 14 to 52 years (mean age: 26.16 years). Methods The formula by Habets et al.14 was used to express the symmetry between the condyles and the rami on the orthopantomogram (OPG) image. Differences between bothgroups and subgroups (condyle, ramus, condyle plus ramus) regarding symmetry were calculated with the Student's t-test. Results The mean of condylar asymmetry was found to be 11.11 ± 11.03% in the TMD group. However, in the control group, the mean of condylar asymmetry was found to be 8.36 ± 6.27%. No statistically significant differences were found between condylar asymmetry in both groups (p>0.05). Conclusions No statistically significant differences were found between condylar asymmetry index in patients with TMD according to myogenous problems and in patients with no signs or symptoms of TMD. Citation Sağlam AA, Şanli G. Condylar Asymmetry Measurements in Patients with Temporomandibular Disorders. J Contemp Dent Pract 2004 August;(5)3:059-065.

scholarly journals AVALIAÇÃO DO EQUILÍBRIO DE MULHERES COM CÂNCER DE MAMA

2019 ◽  
Vol 11 (3) ◽  
pp. 92-98
Author(s):  
Valeria Bruna de Santana Moura ◽  
Doralice Daieli Mendonça Farias Tavares ◽  
Beatriz Jeronymo Schwartz ◽  
Sara Llorente Cordeiro ◽  
Aline Duarte Ferreira ◽  
...  
Keyword(s):  
Dual Task ◽  
Cross Sectional Study ◽  
Cáncer De Mama ◽  
Control Group ◽  
Cross Sectional ◽  
Evaluation Systems ◽  
Cancer Group ◽  
The Mean ◽  
Student’S T ◽  
Student’S T Test

The objective of this study was to verify the balance of women with breast cancer. This cross-sectional study, tested balance of 15women, eight women with cancer and seven without cancer. The evaluation was performed through the Mini Balance Evaluation Systems (MiniBESTest), TUG with simple and dual-task. The mean of age was 59.2 ± 5 years for cancer group and 60.2 ± 5 years for thecontrol group. Student's t-test for independent samples showed that there was no statistical differencebetween the groups for: MiniBESTest score, TUG with simple and dual-task. Women with cancer did not present balance impairments compared to control group according to MiniBESTest, and TUG with simple and dual-task.

scholarly journals Analysis of Biliary Microbiota in Hepatobiliopancreatic Diseases Compared to Healthy People [MICROBILIO]: Study Protocol

2020 ◽  
Author(s):  
Fernanda Sayuri do Nascimento ◽  
Milena Oliveira Suzuki ◽  
João Victor Taba ◽  
Vitoria Carneiro de Mattos ◽  
Leonardo Zumerkorn Pipek ◽  
...  
Keyword(s):  
Ribosomal Rna ◽  
Principal Component ◽  
Control Group ◽  
Case Group ◽  
Disease Biomarkers ◽  
Student’S T ◽  
New Treatments ◽  
Bile Samples ◽  
Student’S T Test

Abstract Background: The performance of the microbiota is observed in several digestive tract diseases. Therefore, reaching the biliary microbiota may suggest ways for studies of biomarkers, diagnoses, tests and therapies in hepatobiliopancreatic diseases.Methods: Bile samples will be collected in endoscopic retrograde cholangiopancreatography patients (case group) and living liver transplantation donors (control group). From the DNA extracted from the samples, the microbiomes will be sequenced by 16S ribosomal RNA (rRNA) pyrosequencing methods. Student’s t-test will be performed with SPSS version 20 for Windows and the Mann-Whitney test will be performed using R software and Python scripts. A principal component analysis signals will be developed as discriminative analysis.Results: The primary expected results of the study is to characterize the specific composition of the biliary microbiota in situations of disease and health. In addition, it seeks to demonstrate the existence of changes in the case of illness and also possible disease biomarkers, diagnosis, interventions and therapies in hepatobiliopancreatic diseases.Conclusions: We believe that the investigation of the biliary tract microbiota will provide benefits such as early diagnosis and new treatments. This should improve quality of life and survival, specially in malignant diseases. Thus, this research will give expectations to further investigation in the biliary microbiota.Trial registration: NCT04391426. Registered 18 May 2020, https://clinicaltrials.gov/ct2/show/NCT04391426

scholarly journals Hepatic steatosis: a risk factor for increased COVID-19 prevalence and severity—a computed tomography study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Asmaa Ali ◽  
Mona Hasan ◽  
Shaimaa Hamed ◽  
Amir Elhamy
Keyword(s):  
Hepatic Steatosis ◽  
Severe Disease ◽  
Severe Pneumonia ◽  
Liver Disorder ◽  
Control Group ◽  
Case Group ◽  
World Population ◽  
Positive Class ◽  
The Mean ◽  
And Control

Abstract Background Around 25% of the world population was affected by the metabolic-related fatty liver disorder. Hepatic steatosis is frequently observed in conjunction with hypertension, obesity comorbidities, and diabetes. We evaluate the hepatic steatosis frequency found in chest CT exams of COVID-19-positive cases compared to non-infected controls and evaluate the related increased prevalence and severity of COVID. Results Our research includes 355 subjects, 158 with positive PCR for COVID-19 (case group) and 197 with negative PCR and negative CT chest (control group). The mean age in the positive group was 50.6 ± 16 years, and in the control, it was 41.3 ± 16 years (p < 0.001). Our study consists of 321 men (90.5%) and 34 women (9.5%). The number of males in both cases and control groups was greater. In the case group, 93% men vs. 6.9% women, while in controls, 88.3% men vs.11.6% women, p < 0.001. CT revealed normal results in 55.5% of individuals (i.e., CORADs 1) and abnormal findings in 45.5% of participants (i.e., CORADs 2–5). In abnormal scan, CO-RADs 2 was 13.92%, while CO-RADs 3–4 were 20.89% of cases. CO-RADs 5 comprised 65.19% of all cases. Approximately 42.6% of cases had severe disease (CT score ≥ 20), all of them were CO-RADs 5. The PCR-positive class had a greater prevalence of hepatic steatosis than controls (28.5% vs.12.2%, p < 0.001). CO-RADs 2 represented 11.1%, CO-RADs 3–4 represented 15.6%, and CO-RADs 5 represented 73.3% in the hepatic steatosis cases. The mean hepatic attenuation value in the case group was 46.79 ± 12.68 and in the control group 53.34 ± 10.28 (p < 0.001). When comparing patients with a higher severity score (CT score ≥ 20) to those with non-severe pneumonia, it was discovered that hepatic steatosis is more prevalent (73.2% vs. 26.8%). Conclusions Steatosis was shown to be substantially more prevalent in COVID-19-positive individuals. There is a relation among metabolic syndrome, steatosis of the liver, and obesity, as well as the COVID-19 severity.

scholarly journals Time Perspective and the Risk of Developing Burnout: An Empirical Study among Different Blue-Collar Workers in Spain

2021 ◽  
Vol 13 (6) ◽  
pp. 3271 ◽  
Author(s):  
Adela Reig-Botella ◽  
Sarah Detaille ◽  
Miguel Clemente ◽  
Jaime López-Golpe ◽  
Annet de Lange
Keyword(s):  
Emotional Exhaustion ◽  
Time Perspective ◽  
Maslach Burnout Inventory ◽  
Future Time Perspective ◽  
Blue Collar ◽  
Control Group ◽  
Northern Spain ◽  
Blue Collar Workers ◽  
The Mean ◽  
Student’S T

The purpose of this research was to analyze the relationship between the time perspective of Spanish shipyard workers in relation to burnout compared to other blue-collar workers in other sectors, including a total of 644 participants in a shipyard in northern Spain and 223 workers in other sectors. The ages were between 20 and 69 (M = 46.14, SD = 10.98). We used the Spanish version of the Zimbardo Time Perspective Instrument (ZTPI) and the Maslach Burnout Inventory–General Survey (MBI-GS). The mean of the three reliability coefficients of the emotional exhaustion factor was 0.887. In respect to the five factors of the ZTPI questionnaire, the mean of those five coefficients was 0.86. A Student’s t-test for independent samples comparing shipyard naval workers vs. the control group in personality variables and burnout was used. The psychological difference between workers in the naval sector and those in other sectors is better predicted based on two variables: emotional exhaustion and professional efficacy. Workers in the naval sector have a higher risk of becoming burnt-out than workers in other sectors due to a negative past, present and future time perspective. This can be a consequence of constant understimulation and monotonous and repetitive work, as well as a lack of autonomy and social support at work.

scholarly journals ASSOCIATION BETWEEN SERUM URIC ACID AND METABOLIC SYNDROME

2018 ◽  
Vol 11 (10) ◽  
pp. 400 ◽  
Author(s):  
Thaslima Nandhini Js ◽  
Savitha Basker G ◽  
Vishnupriya V
Keyword(s):  
Metabolic Syndrome ◽  
Uric Acid ◽  
Venous Blood ◽  
Fasting Blood Glucose ◽  
Control Group ◽  
Serum Triglycerides ◽  
Significant Difference ◽  
Disease Condition ◽  
Student’S T ◽  
Student’S T Test

Objective: Metabolic syndrome is a cluster of disease condition characterized by truncal obesity, hypertriglyceridemia, elevated blood pressure, and insulin resistance. An excessive circulating uric acid (UA) level even within normal range is always comorbid with metabolic syndrome and its components. The aim of the current study was to investigate the association between metabolic syndrome and serum UA level.Methods: A total of 60 subjects were divided into two groups of healthy (30 individuals) and metabolic syndrome patients (30 individuals) from dental outpatient department of Saveetha Dental College and Hospitals. 5 ml of fasting venous blood was collected in the plain collection tubes and centrifuged, and then serum was separated. Then, the serum was used to analyze the fasting blood glucose, serum triglycerides (TGLs), and serum UA by GOD-POD, enzymatic colorimetric, and uricase method, respectively. A statistical analysis was performed using Student’s t-test. p<0.05 was considered to be statistically significant.Result: Mean body mass index (BMI), fasting blood sugar (FBS), TGL, and UA level of control group were 23.36±1.81, 84.45±13.1, 110.9±22.6, and 3.48±1.21 respectively. Mean BMI, FBS, TGL, and UA level of study group were 35.24±3.04, 122.85±23.3, 212.1±39.6 and 9.08±2.63 respectively. There is a significant difference between these two groups with p<0.0001.Conclusion: This study showed that those individuals with metabolic syndrome have higher UA level that indicates hyperuricemia which is a significant predictor of metabolic syndrome.

scholarly journals Early Neuromuscular Blockade in Children with Pediatric Acute Respiratory Distress Syndrome

2020 ◽  
Vol 09 (03) ◽  
pp. 201-206
Author(s):  
Surabhi Chandra ◽  
Sahil Goel ◽  
Ritika Dawra
Keyword(s):  
Mechanical Ventilation ◽  
Acute Respiratory Distress Syndrome ◽  
Respiratory Distress Syndrome ◽  
Neuromuscular Blockade ◽  
Distress Syndrome ◽  
Control Group ◽  
Case Group ◽  
The Mean ◽  
Mean Time

AbstractPediatric acute respiratory distress syndrome (PARDS) is a challenging problem with high mortality. Role of neuromuscular blockade in the management of ARDS to date has been controversial, and this study was done to study the role of neuromuscular blockade in children having PARDS and development of associated complications, if any. This was a prospective, case–control study conducted in the pediatric intensive care unit (PICU) of a tertiary care teaching hospital, over a period of 24 months. Patients of age 1 to 18 years who presented with or developed PARDS during their course of hospitalization were included after written informed consent was obtained from their parents and/or guardians. Patients with PARDS requiring invasive mechanical ventilation were partitioned into a case group and a control group. Case group patients were sedated and paralyzed using midazolam (1 µg/kg/min) and vecuronium (1 µg/kg/min), respectively, along with institution of definitive management. Control group patients were given definitive and supportive therapy, but no neuromuscular blocking agents (NMBAs). All patients were followed up for signs and symptoms of myopathy or neuropathy during the entire duration of hospital stay and up to 3 months after discharge. During the study period, 613 patients were admitted to the PICU of which 91 patients qualified as having PARDS. Sepsis was the main etiology in 67 of the 91 patients (73.6%) with PARDS. Fifty-nine patients were included in the study, of which 29 patients were included in the case group and 30 patients were included in the control group. Among the 29 case group patients, 25 patients (86.2%) were successfully extubated. Four patients from the case group expired, while 14 out of 30 control group patients (46.7%) expired. Hypotension was present in 26 case group patients (89.6%), of which all showed resolution within 48 hours of definitive treatment. The mean time to resolution of hypotension was 41.6 hours (standard deviation [SD]: 5.759; range: 24–48) for case group patients, significantly lower (p < 0.0001) than the mean time to resolution of 103 hours (SD: 18.995; range: 90–126) for the 10 control group patients with hypotension that survived. Mean oxygenation index (OI) following 48 hours of vecuronium therapy was significantly lower (p < 0.0001; 95% confidence interval: 5.9129–9.9671) than mean OI at admission for case group patients. None of the patients receiving vecuronium exhibited neuromuscular deficit during their hospital stay, at time of discharge, or at follow-up evaluation up to 3 months after discharge. In this study, pediatric cases diagnosed with PARDS and managed with mechanical ventilation and vecuronium therapy had improved mean OI following 48 hours of NMBA therapy and a lower mortality when compared with matched control group patients. Incidence of NMBA-related weakness was not commonly observed in these patients.

scholarly journals Distances between mandibular posterior teeth and the WALA ridge in Peruvians with normal occlusion

2017 ◽  
Vol 22 (6) ◽  
pp. 56-60 ◽  
Author(s):  
Carla Y. Kong-Zárate ◽  
Marcos J. Carruitero ◽  
Will A. Andrews
Keyword(s):  
Age Groups ◽  
Test Results ◽  
Posterior Teeth ◽  
Normal Occlusion ◽  
Tooth Type ◽  
The Mean ◽  
Student’S T ◽  
Mandibular Posterior Teeth ◽  
Digital Caliper ◽  
Student’S T Test

ABSTRACT Objective: The purposes of this investigation were to determine the horizontal distances between the mandibular posterior teeth and the WALA ridge in a sample of Peruvians with normal occlusion and to compare them by tooth type, sex, arch side, and age groups. Methods: 65 dental casts of subjects with normal occlusion were collected. Posterior teeth, except for third molars, were evaluated. The horizontal distances between the occluso-gingival midpoints of the buccal surfaces (FA points) of each tooth and the WALA ridge were measured using a modified digital caliper. The values between each different tooth type within the sample were compared using the ANOVA and Scheffe tests, while comparisons by sex, arch side and age groups, using the Student’s t-test. Results: The mean distances in the sample was 0.96 mm for first premolars, 1.45 mm for second premolars, 2.12 mm for first molars and 2.55 mm for second molars. Statistically significant differences between each of the four tooth types were found. There were no significant differences found between sex, arch side and age groups. Conclusion: The horizontal distances between the mandibular posterior teeth and the WALA ridge increased progressively from the first premolars to the second molars in Peruvians with normal occlusion. The WALA ridge was a good landmark to evaluate the positions of posterior teeth in Peruvians with normal occlusion.

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