Trend Analysis of Major Sexually Transmitted Infections in China , 1999-2018
Abstract Background:The aim of our study was to analyze the trend changes and region distribution changes of three sexually transmitted infections (STIs) in China and provided a scientific basis for the government to make prevention and control measures.Methods:This study used Joinpoint regression model to fit the morbidity data of three STIs in China from 1999 to 2018. Annual percentage change (APC) and Average annual percentage Change (AAPC) were calculated to evaluate the trend changes of three STIs. We also used hierarchical clustering analysis to analyze the region distribution of three STIs in China from 2003-2018.Results :We analyzed the morbidity data of three STIs in 1999-2018 derived from China Health Statistics Yearbook. The final model of AIDS was the 3 Joinpoint model (P = 0.01) with an annual average percent change (AAPC) of 33.7 (95% CI: 26.1-41.8, P < 0.001). The final model of gonorrhea was the 1 Joinpoint model (P= 0.0025) with an annual average percent change (AAPC) of -4.9 (95% CI: -6.2- -3.6, P < 0.001). The final model of gonorrhea was the 1 Joinpoint model (P < 0.05) with an annual average percent change (AAPC) of 9.1 (95% CI:6.9-11.4, P < 0.001). The region distribution of the morbidity of three STIs mainly concentrated in the southeast coastal areas and Xinjiang, other areas showed low epidemic levels.Conclusions: In a word, the morbidity of three STIs in China is still increasing slowly, the form of prevention and control for STIs is still very severe, especially in coastal provinces and Xinjiang. Therefore, it is necessary to actively popularize knowledge related to STIDs, and carry out large-scale peer education, further reduce epidemic of sexually transmitted infections in China.