Free Radical Scavenging and Tyrosinase Inhibition Activity of Physic Nut (Jatropha curcas Linn.) Seed Oil Entrapped in Niosomes

2011 ◽  
Vol 7 (5) ◽  
pp. 825-829
Author(s):  
Aranya Manosroi ◽  
Korawinwich Boonpisuttinant ◽  
Supanida Winitchai ◽  
Worapaka Manosroi ◽  
Jiradej Manosroi
Keyword(s):  
Free Radical ◽  
Jatropha Curcas ◽  
Seed Oil ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Inhibition Activity ◽  
Physic Nut ◽  
Tyrosinase Inhibition

scholarly journals Free radical scavenging and tyrosinase inhibition activity of oils and sericin extracted from Thai native silkworms (Bombyx mori)

2010 ◽  
Vol 48 (8) ◽  
pp. 855-860 ◽  
Author(s):  
Aranya Manosroi ◽  
Korawinwich Boonpisuttinant ◽  
Supanida Winitchai ◽  
Worapaka Manosroi ◽  
Jiradej Manosroi
Keyword(s):  
Free Radical ◽  
Bombyx Mori ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Inhibition Activity ◽  
Tyrosinase Inhibition

scholarly journals Bioactivity determination and development of skin care product containing Cassia fistula bark extract

2020 ◽  
Author(s):  
Lapatrada Mungmai ◽  
Weeraya Preedalikit ◽  
Tammanoon Rungsang ◽  
Mathukorn Sainakham
Keyword(s):  
Free Radical ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Skin Care ◽  
Total Phenolic ◽  
Inhibition Activity ◽  
Tyrosinase Inhibition ◽  
Care Product ◽  
Skin Care Product

The determine of active contents, free radical scavenging and tyrosinase inhibition activity of Cassia fistula extracts for development of skin care product was presented in this study. C. fistula was extracted by 95% ethanol. Then, the extracts were determined total phenolic content, phytochemical constituents, free radical scavenging and tyrosinase inhibition activity. The formulation containing the selected C. fistula extract was prepared and examined the bioactivities and stability of this formulation. C. fistula extract from bark provided the highest total phenolic content and free radical scavenging activity of 22.35±1.38 GAE/g and the IC50 value of 0.01±0.01 mg/ml, respectively. The highest tyrosinase inhibition activity was observed in C. fistula extract from flower at the IC50 value of 0.54±0.01 mg/ml. The C. fistula extract from bark was selected to be active ingredient in skin care product. At 4±2 °C storage, the formulation containing C. fistula extract from bark showed the highest stability without changing the color, odor, homogeneity, viscosity and pH. The bioactivities of the formulation containing C. fistula extract from bark were slightly decreased in all temperatures at the end of stability test. In this study, C. fistula extract from bark has the potential of tyrosinase inhibition and free radical scavenging activity. Therefore, it may be the appropriate choice for skin care products that aim to provide whitening effects.

scholarly journals Antioxidant and α-Glucosidase Inhibitory Constituents from Hornstedtia Species of Malaysia

2015 ◽  
Vol 10 (9) ◽  
pp. 1934578X1501000 ◽  
Author(s):  
Siti Ernieyanti Hashim ◽  
Hasnah Mohd Sirat ◽  
Khong Heng Yen ◽  
Intan Safinar Ismail ◽  
Siti Nurulhuda Matsuki
Keyword(s):  
Free Radical ◽  
Inhibitory Activity ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Spectroscopic Techniques ◽  
Inhibition Activity ◽  
Dpph Assay ◽  
Glucosidase Inhibitors ◽  
Antioxidant Agent ◽  
First Time

Seven compounds were isolated from the n-hexane and chloroform extracts of the flowers and leaves of four Hornstedtia species and their structures were identified using spectroscopic techniques as 3,7,4′-trimethylkaempferol (1), 3,7-dimethylkaempferol (2), 7,4′-dimethylkaempferol (3), 3,5-dimethylkaempferol (4), 3-methylkaempferol (5), stigmast-4-en-3-one (6), and 6-hydroxy-stigmast-4-en-3-one (7). Compounds 1 to 7 were isolated from these species for the first time. They were assayed for free radical scavenging and α-glucosidase inhibition activities. The DPPH assay showed that 3-methylkaempferol (5) was the most potent antioxidant agent with an IC50 value 78.6 μM, followed by 7,4′-dimethylkaempferol (3) (IC50 = 86.1 μM). For α-glucosidase inhibition activity, 3-methylkaempferol (5) exhibited significant inhibitory activity with an IC50 value 21.0 μM. The present study revealed that Hornstedtia species have potential activities as antioxidant and α-glucosidase inhibitors.

Free-radical-scavenging and tyrosinase-inhibition activities of Cheonggukjang samples fermented for various times

2008 ◽  
Vol 106 (2) ◽  
pp. 564-568 ◽  
Author(s):  
Hyung-Kyoon Choi ◽  
Yong-Suk Lim ◽  
Young-Suk Kim ◽  
So-Young Park ◽  
Choong-Hwan Lee ◽  
...  
Keyword(s):  
Free Radical ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Tyrosinase Inhibition

scholarly journals Functionality Analysis of Spent Coffee Ground Extracts Obtained by the Hydrothermal Method

2019 ◽  
Vol 2019 ◽  
pp. 1-8 ◽  
Author(s):  
Chin-Tung Wu ◽  
Dinesh Chandra Agrawal ◽  
Wen-Ying Huang ◽  
Hsiu-Cheng Hsu ◽  
Shang-Jhen Yang ◽  
...  
Keyword(s):  
Free Radical ◽  
Hydrothermal Method ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Free Radical Scavenging Activity ◽  
Total Phenolic ◽  
Scavenging Activity ◽  
Tyrosinase Inhibition ◽  
Spent Coffee Ground

Coffee is a popular beverage all over the world, but spent coffee grounds (SCGs) constituting almost 75% of original beans are usually considered waste and disposed off. The present study analyzed the functionalities of SCG with a view of its reuse in the cosmetic industry. The SCG extraction was carried out by the hydrothermal method. The resultant extracts were tested for its antioxidant capacity, tyrosinase inhibition, and moisturizing ability. LC–MS/MS results showed two major components in SCG extracts, namely, trigonelline and caffeine. Also, the SCG contained total flavonoid contents of 29 ± 4.5 mg quercetin equivalents (QE)/g SCG and total phenolic contents of 9.44 ± 0.90 mg gallic acid equivalents (GAE)/g SCG. Regarding functionality analysis, SCG extracts exhibited reduction capacity of 8.18 ± 0.39 mg vitamin C equivalent (VCE)/g SCG, DPPH free-radical scavenging activity (IC50) of 3.11 mg SCG/mL, ABTS free-radical scavenging activity (IC50) of 13.61 mg SCG/mL, and tyrosinase inhibition capacity (IC50) of 2.23 mg SCG/mL. Moreover, the volatilization rate of the extract solution (37 mg SCG/mL) reduced by 15.9%. These results demonstrate the utility of recycling of SCG and illustrate its potential application in the development of skin care products.

scholarly journals Antioxidation and Tyrosinase Inhibitory Ability of Coffee Pulp Extract by Ethanol

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Cheng-You Chen ◽  
Chia-Hung Shih ◽  
Tzu-Che Lin ◽  
Ji-Hong Zheng ◽  
Chien-Chieh Hsu ◽  
...  
Keyword(s):  
Free Radical ◽  
Antioxidant Capacity ◽  
Economic Value ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Total Phenolic ◽  
Tyrosinase Inhibition ◽  
Coffee Pulp ◽  
Radical Scavenging Capacity ◽  
Scavenging Capacity

Background. Following petroleum, coffee is the second most commonly traded commodity globally. It is also a popular good with economic value, as well as value in terms of leisure and culture. However, coffee processing generates a large amount of waste, resulting in environmental concerns. Therefore, in this study, ethanol was used to extract coffee waste (coffee pulp). High-performance liquid chromatography was conducted to examine the caffeine content and chlorogenic acid content, and the antioxidant capacity (i.e., the total phenolic content, total flavonoid content, DPPH-free radical scavenging capacity, ABTS-free radical scavenging capacity, and reductive capacity) and the tyrosinase inhibition capacity of the coffee pulp extracted using ethanol were comprehensively evaluated. Results. The results showed that the coffee pulp extract obtained using 70% ethanol had the highest tyrosinase inhibition capacity, whereas that obtained using 50% ethanol had the most satisfactory antioxidant capacity (total phenolic content, total flavonoid content, DPPH-free radical scavenging capacity, ABTS-free radical scavenging capacity, and reductive capacity). Conclusion. The results revealed that coffee pulp has superior antioxidant capacity and tyrosinase inhibition capacity when extracted by ethanol. Increasing the economic value of coffee pulp can solve the environmental concerns caused by coffee waste.

scholarly journals Evaluation of Antioxidant, Anticholinesterase and Antityrosinase Activities of Malaysian Cinnamomum Species

2016 ◽  
Vol 14 (2) ◽  
pp. 125-132 ◽  
Author(s):  
Wan Mohd Nuzul Hakimi Wan Salleh ◽  
Farediah Ahmad ◽  
Khong Heng Yen
Keyword(s):  
Linoleic Acid ◽  
Free Radical ◽  
Phenolic Content ◽  
Therapeutic Potential ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
New Drugs ◽  
Tyrosinase Inhibition ◽  
Antioxidant Power ◽  
Ferric Reducing Antioxidant Power

The extracts of the leaves and bark of five Cinnamomum species (C. altissimum, C. griffithii, C. javanicum, C. macrocarpum, and C. velutinum) were screened to evaluate their antioxidant, anticholinesterase, and antityrosinase activities. The bark of C. altissimum showed the highest phenolic content (130.1 mg GA/g), free radical scavenging by DPPH (IC50 126.2 ?g/mL) and ferric reducing antioxidant power (FRAP) assays (341.2 mg AA/g). All of the extracts inhibited linoleic acid peroxidation by greater than 70%, with the leaves of C. altissimum exhibiting the highest inhibition of 87.7%. The leaves of C. javanicum revealed the highest inhibition on anticholinesterase (AChE 30.8%) and butyrylcholinesterase (BChE 46.8%) enzymes. The leaves and bark of C. altissimum and C. velutinum exhibited greater than 20% tyrosinase inhibition, with the leaves of C. altissimum having the highest percentage of inhibition (34.6%). These bioactivities indicate that some Cinnamomum species have therapeutic potential in medicinal research and development of new drugs candidates.Dhaka Univ. J. Pharm. Sci. 14(2): 125-132, 2015 (December)

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