Today due to global climate change the Northern Sea Route is being formed along the northern coast of Russia as a new international maritime passage in the Arctic. Due to the rapid increase in the interest of regional and non-Arctic states, the scientific community and business to this transportation route, there is a need to study the prospects for cooperation between Russia and other countries on the development of the Northern Sea Route. The paper provides a detailed analysis of the interests of external players in the NSR area, taking into account the latest changes and events, while the author uses swot-analysis and a comparative analytical approach to conduct the study. The results of the study have shown that cooperation with some Arctic countries on the development of the NSR could bring mutual benefits: Canada and Russia would exchange experience on the development of similar sea routes, and Norway and Iceland would receive advantages as hubs on new routes. Non-regional countries, such as China, South Korea, Japan, Singapore and India, are interested in the NSR. For them, the Northern Sea Route is potentially shorter and safer compared to traditional routes, and it also allows to participate in projects located near its water area in science, energy and transport sectors. In turn, the participation of foreign partners is important for Russia, since it is usually accompanied by the active use of the route, the creation of large projects throughout its entire length, the attraction of serious funds, modern technologies and knowledge to the Arctic zone of the country.