TNM: a simple classification system for complicated intra-abdominal sepsis after acute appendicitis

2020 ◽  
Vol 75 (6) ◽  
Author(s):  
Mario Schietroma ◽  
Lucia Romano ◽  
Beatrice Pessia ◽  
Antonella Mattei ◽  
Fabiana Fiasca ◽  
...  
Stroke ◽  
2020 ◽  
Vol 51 (Suppl_1) ◽  
Author(s):  
Shadi Yaghi ◽  
Andrew Chang ◽  
Gian Ignacio ◽  
Erica Scher ◽  
Nikhil Panda ◽  
...  

Background and Purpose: Previously we proposed a simple classification system of the left atrial appendage (LAA) morphology, with low risk (LAA-L) defined as one lobe with an acute angle bend arising from the proximal or middle portion and high risk (LAA-H) defined as all other morphologies. We aim to determine the association between LAA morphology (using both classification systems), LAA flow velocity, and stroke rates. Methods: We analyzed consecutive patients with atrial fibrillation (AF) selected for ablation who underwent cardiac CT angiography and transesophageal echocardiogram. The primary correlates were LAA-H and non-chicken wing (NCW) LAA morphology. The primary outcome was the composite endpoint of history of ischemic stroke/TIA or non-lacunar infarct on neuroimaging. Adjusting for CHADS2Vasc score, multivariable models were used to determine associations between LAA morphology and composite outcomes. Results: We identified 379 patients; the primary endpoint occurred in 32/379 patients (8.4%). LAA-H (adjusted OR 3.63, 95% CI 1.44-9.14) and NCW LAA morphology (adjusted OR 2.52, 95% CI 1.15-5.53) were associated with the primary endpoint. LAA flow velocity ≤20 cm/s was more common in LAA-H vs. LAA-L (9.6% vs. 2.8%, p = 0.019), but not in NCW vs. CW LAA morphology (9.7% vs. 3.7%, p = 0.054). Conclusion: The LAA H/L morphological classification system may be superior to the current system in risk stratifying patients with AF and correlates better with impaired LAA flow dynamics.


2012 ◽  
Vol 143 (3) ◽  
pp. 599-607.e1 ◽  
Author(s):  
David G. Hewett ◽  
Tonya Kaltenbach ◽  
Yasushi Sano ◽  
Shinji Tanaka ◽  
Brian P. Saunders ◽  
...  

2015 ◽  
Vol 97 (5) ◽  
pp. 390-395 ◽  
Author(s):  
VY Kong ◽  
B Sartorius ◽  
DL Clarke

Introduction Acute appendicitis in the developing world has a markedly different disease profile to that in the developed world. Methods A retrospective study was undertaken over a four-year period at a university hospital in South Africa to review the disease spectrum and the clinical outcome of acute appendicitis. Results A total of 1,004 patients (54% male, median age: 18 years) with intraoperatively confirmed appendicitis were reviewed. Over half (56%) were from the urban district within the city of Pietermaritzburg and the remaining 44% were from the rural health district. The median duration of illness from onset to definitive care was 4 days. Sixty per cent of appendices were perforated and associated with intra-abdominal contamination. Forty per cent of patients required reoperation to control intra-abdominal sepsis. Ten per cent required admission to the intensive care unit. The median overall length of hospital stay was 5 days. The mortality rate was 1%. Rural patients had a longer median duration of illness (3 vs 5 days, p<0.001) as well as a more advanced disease profile associated with perforation and severe intra-abdominal sepsis (19% vs 71%, p<0.001). Female patients had a longer median duration of illness (3 vs 4 days, p<0.001), were more likely to present with severe intra-abdominal sepsis (31% vs 54%, p<0.001) and were more likely to require a laparotomy (50% vs 73%, p<0.001). The total cost of managing the entire cohort of 1,004 patients over the 4-year period was £2,060,972. Conclusions Acute appendicitis in South Africa is a serious disease associated with significant morbidity. Late presentation is common. Female and rural patients have the worst clinical outcomes, with significant cost to the health system.


1988 ◽  
Vol 66 (1) ◽  
pp. 274-276
Author(s):  
J. L. Shipp

A classification system for embryonic development of Simulium arcticum Malloch (IIS-10.11) is described. Embryonic development was divided into five stages based upon the degree of embryogenesis. This simple classification system would be useful for monitoring development of S. arcticum (IIS-10.11) in studies to determine the effects of environmental factors or chemical insecticides on egg development and hatch.


2017 ◽  
Vol 27 (9) ◽  
pp. 3799-3809 ◽  
Author(s):  
Ramona Woitek ◽  
Claudio Spick ◽  
Melanie Schernthaner ◽  
Margaretha Rudas ◽  
Panagiotis Kapetas ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document