scholarly journals Canine Leishmaniosis: A Silent Burden in Southeast Asia and Elucidating Existing Knowledge Gap

2019 ◽  
Vol 4 (1) ◽  
pp. 1-6
Author(s):  
Abdul Rani PA
Keyword(s):  
Southeast Asia ◽  
Scientific Community ◽  
Tropical Disease ◽  
Neglected Tropical Disease ◽  
Canine Leishmaniosis ◽  
Parasitic Disease ◽  
Southern Europe ◽  
Vector Borne Diseases ◽  
Vector Borne ◽  
The Tropics

Canine leishmaniosis is one of the most important canine vector - borne diseases (CVBD) caused by protozoan Leishmania sp . which pose zoonotic threat as some of its species are zoonotic. This parasitic disease is classified as Neglected Tropical Disease (NTD) and can be found in parts of the tropics, subtropics and southern Europe. A lot of studies had been carried out across the globe but lack in Southeast Asia, thus its epi zootiology is still poorly understood. This article is meant to create awareness of the existence of this zoonotic disease amongst veterinary personnel, scientific community and readers.

Impact of ticks and tick-borne diseases on agriculture and human populations in Europe

2005 ◽  
Vol 143 (6) ◽  
pp. 463-468 ◽  
Author(s):  
O. A. E. SPARAGANO
Keyword(s):  
Eastern Europe ◽  
Human Populations ◽  
Southern Europe ◽  
West Nile ◽  
Vector Borne Diseases ◽  
Tick Borne Disease ◽  
Vector Borne ◽  
The Tropics ◽  
Human Ehrlichiosis

Ticks are considered in Europe to be the most important arthropod group responsible for vector-borne diseases in humans, while in the tropics mosquitoes take over this position with ticks being the second most important. Over the last decade, vector-borne diseases have proliferated within Southern Europe (Blue tongue and West Nile viruses, both mosquito-borne diseases) while human ehrlichiosis (a tick-borne disease) has increased dramatically in Eastern Europe.

scholarly journals Repurposing as a strategy for the discovery of new anti-leishmanials: the-state-of-the-art

Parasitology ◽  
2017 ◽  
Vol 145 (2) ◽  
pp. 219-236 ◽  
Author(s):  
REBECCA L. CHARLTON ◽  
BARTIRA ROSSI-BERGMANN ◽  
PAUL W. DENNY ◽  
PATRICK G. STEEL
Keyword(s):  
State Of The Art ◽  
Drug Repurposing ◽  
Tropical Disease ◽  
Neglected Tropical Disease ◽  
Current State ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Vector Borne ◽  
Faster Development ◽  
New Treatments

SUMMARYLeishmaniasis is a vector-borne neglected tropical disease caused by protozoan parasites of the genus Leishmania for which there is a paucity of effective viable non-toxic drugs. There are 1·3 million new cases each year causing considerable socio-economic hardship, best measured in 2·4 million disability adjusted life years, with greatest impact on the poorest communities, which means that desperately needed new antileishmanial treatments have to be both affordable and accessible. Established medicines with cheaper and faster development times may hold the cure for this neglected tropical disease. This concept of using old drugs for new diseases may not be novel but, with the ambitious target of controlling or eradicating tropical diseases by 2020, this strategy is still an important one. In this review, we will explore the current state-of-the-art of drug repurposing strategies in the search for new treatments for leishmaniasis.

scholarly journals POTENSI TRIATOMA SP DALAM PENYEBARAN PENYAKIT TULAR VEKTOR EMERGING DI INDONESIA

2019 ◽  
Vol 11 (2) ◽  
pp. 131-138
Author(s):  
Risqa Novita
Keyword(s):  
Allergic Reaction ◽  
Southeast Asia ◽  
Chagas Disease ◽  
Early Warning System ◽  
Warning System ◽  
Emerging Diseases ◽  
Laboratory Research ◽  
Tropical Country ◽  
Vector Borne Diseases ◽  
Vector Borne

The era of globalization allows migration fastly, so we do not have boundary of a country. This led to an increase of the infectious diseases. Indonesia also have an impact on this globalization by highly migration. Indonesia is a tropical country and has diversity of vectors that can transmit various tropical diseases. One of a vector  which transmitted vector borne diseases is a bug Triatoma. Triatoma lives near the people’s house and in the bed. One of the species of Triatoma which found in indonesia is Triatoma rubrifasciata which is vector of Chagas disease and Leprosy and can cause allergic reaction of the skin after the bite. Triatoma infection in Southeast Asia, including in Indonesia has not been widely reported. This condition should make us to be alert on the disease emerging or re emerging diseases that can be caused by Triatoma . This article aims to study Triatoma as a vector of emerging and potentially re emerging diseases in Indonesia, which are Chagas, skin allergic reaction after bite and Leprosy. Methods. Literature review by look in google scholar and pubmed, by search using keywords: emerging parasitic, vector borne diseases, Triatoma in Southeast Asia. Inclusion criterias are research articles, laboratory research, case report, and systematic surveillance. Based on the literatures, tracing data that Indonesia has a chance to be  the cases of Chagas disease, Skin allergic reaction of Triatoma and Leprosy. It is supposed to made the vigilance on  make a early warning system, so our public health coud be achieved highest.

scholarly journals Endomyocardial fibrosis associated with mansoni schistosomiasis

2011 ◽  
Vol 44 (5) ◽  
pp. 644-645 ◽  
Author(s):  
Renata de Carvalho Bicalho Carneiro ◽  
Alexandre Lemos da Silveira Santos ◽  
Luisa Campos Caldeira Brant ◽  
Fábio Tôrres Rabelo ◽  
Carla Maia Ligeiro ◽  
...  
Keyword(s):  
Cause Of Death ◽  
Fibrous Tissue ◽  
Restrictive Cardiomyopathy ◽  
Tropical Disease ◽  
Endomyocardial Fibrosis ◽  
Neglected Tropical Disease ◽  
Parasitic Disease ◽  
Common Cause ◽  
Schistosomiasis Mansoni

Endomyocardial fibrosis (EMF) is a neglected tropical disease that affects millions of people worldwide. EMF is the most common cause of restrictive cardiomyopathy, caused by deposition of fibrous tissue on endocardial surfaces. EMF is a major cause of death in areas where it is endemic, but the pathogenesis of the disease is poorly understood. Schistosomiasis mansoni is a parasitic disease endemic in Brazil, where EMF has also been described. The association between EMF and schistosomiasis has been suggested in various publications, seeking a possible correlation between endocardial and periportal fibroses. This report describes a case of EMF associated with schistosomiasis.

scholarly journals Autochthonous dengue in two Dutch tourists visiting Département Var, southern France, July 2020

2020 ◽  
Vol 25 (39) ◽  
Author(s):  
Tom D Vermeulen ◽  
Johan Reimerink ◽  
Chantal Reusken ◽  
Sandra Giron ◽  
Peter J de Vries
Keyword(s):  
Public Health ◽  
Dengue Virus ◽  
Denv Infection ◽  
Diagnosis And Treatment ◽  
Southern Europe ◽  
Southern France ◽  
Delay In Diagnosis ◽  
Vector Borne Diseases ◽  
Vector Borne ◽  
Health Experts

We report dengue virus (DENV) infection in two Dutch tourists who visited Département Var, southern France, in July and August 2020. As some autochthonous dengue cases have occurred in Europe in recent years, awareness among physicians and public health experts about possible intermittent presence of DENV in southern Europe is important to minimise delay in diagnosis and treatment. Quick diagnosis can lead to timely action to contain the spread of vector-borne diseases and minimise transmission.

scholarly journals An Asymptomatic Tropical Infection in a Pregnancy Complicated by a Hematological Neoplasm-accidental Passenger or Effect of Immunosuppression?

2021 ◽  
pp. 33-36
Author(s):  
Sammya Bhowmick ◽  
Chandan Mishra ◽  
S. Arulselvi ◽  
Tushar Sehgal
Keyword(s):  
Public Health ◽  
Chronic Myeloid Leukemia ◽  
Lymphatic Filariasis ◽  
Myeloid Leukemia ◽  
Tropical Disease ◽  
Health Concern ◽  
Neglected Tropical Disease ◽  
Public Health Concern ◽  
Hematological Neoplasm ◽  
Vector Borne

Lymphatic filariasis is a vector borne infection classified under the WHO category of Neglected Tropical Disease (NTD). It is a major public health concern globally. This study describes this vector-borne infection in a young pregnant lady, a known case of chronic myeloid leukemia (CML) on chemotherapy. Such an association is hitherto unreported.

scholarly journals A Host-Specific Blocking Primer Combined with Optimal DNA Extraction Improves the Detection Capability of a Metabarcoding Protocol for Canine Vector-Borne Bacteria

Pathogens ◽  
2020 ◽  
Vol 9 (4) ◽  
pp. 258
Author(s):  
Lucas G. Huggins ◽  
Anson V. Koehler ◽  
Bettina Schunack ◽  
Tawin Inpankaew ◽  
Rebecca J. Traub
Keyword(s):  
Dna Extraction ◽  
Cross Reactivity ◽  
Diverse Range ◽  
Vector Borne Diseases ◽  
Zoonotic Risk ◽  
Blocking Primer ◽  
Life Threatening ◽  
Mitochondrial Sequences ◽  
Vector Borne ◽  
The Tropics

Bacterial canine vector-borne diseases are responsible for some of the most life-threatening conditions of dogs in the tropics and are typically poorly researched with some presenting a zoonotic risk to cohabiting people. Next-generation sequencing based methodologies have been demonstrated to accurately characterise a diverse range of vector-borne bacteria in dogs, whilst also proving to be more sensitive than conventional PCR techniques. We report two improvements to a previously developed metabarcoding tool that increased the sensitivity and diversity of vector-borne bacteria detected from canine blood. Firstly, we developed and tested a canine-specific blocking primer that prevents cross-reactivity of bacterial primer amplification on abundant canine mitochondrial sequences. Use of our blocking primer increased the number of canine vector-borne infections detected (five more Ehrlichia canis and three more Anaplasma platys infections) and increased the diversity of bacterial sequences found. Secondly, the DNA extraction kit employed can have a significant effect on the bacterial community characterised. Therefore, we compared four different DNA extraction kits finding the Qiagen DNeasy Blood and Tissue Kit to be superior for detection of blood-borne bacteria, identifying nine more A. platys, two more E. canis, one more Mycoplasma haemocanis infection and more putative bacterial pathogens than the lowest performing kit.

scholarly journals Assessing the Role of Climate Change in Malaria Transmission in Africa

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
E. T. Ngarakana-Gwasira ◽  
C. P. Bhunu ◽  
M. Masocha ◽  
E. Mashonjowa
Keyword(s):  
Climate Change ◽  
Falciparum Malaria ◽  
Malaria Vectors ◽  
Southern Limit ◽  
Vector Borne Diseases ◽  
Malaria Burden ◽  
Important Concern ◽  
Vector Borne ◽  
African Highlands ◽  
The Tropics

The sensitivity of vector borne diseases like malaria to climate continues to raise considerable concern over the implications of climate change on future disease dynamics. The problem of malaria vectors shifting from their traditional locations to invade new zones is of important concern. A mathematical model incorporating rainfall and temperature is constructed to study the transmission dynamics of malaria. The reproduction number obtained is applied to gridded temperature and rainfall datasets for baseline climate and future climate with aid of GIS. As a result of climate change, malaria burden is likely to increase in the tropics, the highland regions, and East Africa and along the northern limit of falciparum malaria. Falciparum malaria will spread into the African highlands; however it is likely to die out at the southern limit of the disease.

scholarly journals Curcumin Derivatives as Potential Mosquito Larvicidal Agents against Two Mosquito Vectors, Culex pipiens and Aedes albopictus

2021 ◽  
Vol 22 (16) ◽  
pp. 8915
Author(s):  
Dimitris Matiadis ◽  
Panagiota G. V. Liggri ◽  
Eftichia Kritsi ◽  
Niki Tzioumaki ◽  
Panagiotis Zoumpoulakis ◽  
...  
Keyword(s):  
Culex Pipiens ◽  
Mosquito Species ◽  
Urban Environments ◽  
Southern Europe ◽  
Mosquito Vectors ◽  
Vector Borne Diseases ◽  
Curcumin Derivatives ◽  
Structure Activity ◽  
Vector Borne ◽  
Curcumin Derivative

Vector-borne diseases have appeared or re-emerged in many Southern Europe countries making the transmission of infectious diseases by mosquitoes (vectors) one of the greatest worldwide health threats. Larvicides have been used extensively for the control of Aedes (Stegomyia) albopictus (Skuse, 1895) (Diptera: Culicidae) and Culex pipiens Linnaeus, 1758 (Diptera: Culicidae) mosquitoes in urban and semi-urban environments, causing the increasing resistance of mosquitoes to commercial insecticides. In this study, 27 curcuminoids and monocarbonyl curcumin derivatives were synthesised and evaluated as potential larvicidal agents against Cx. pipiens and Ae. albopictus. Most of the compounds were more effective against larvae of both mosquito species. Four of the tested compounds, curcumin, demethoxycurcumin, curcumin-BF2 complex and a monocarbonyl tetramethoxy curcumin derivative exhibited high activity against both species. In Cx. pipiens the recorded LC50 values were 6.0, 9.4, 5.0 and 32.5 ppm, respectively, whereas in Ae. albopictus they exhibited LC50 values of 9.2, 36.0, 5.5 and 23.6 ppm, respectively. No conclusive structure activity relationship was evident from the results and the variety of descriptors values generated in silico provided some insight to this end.

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